Peptidylarginine deiminase inhibition impairs Toll-like receptor agonist-induced functional maturation of dendritic cells, resulting in the loss of T cell-proliferative capacity: a partial mechanism with therapeutic potential in inflammatory settings

Peptidylarginine Deiminase Inhibition Reduces Vascular Damage and Modulates Innate Immune Responses in Murine Models of Atherosclerosis

(2014) Jason S. Knight et al.   CIRCULATION RESEARCH

Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus

(2013) Jason S. Knight et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation

(2013) Bryan Vander Lugt et al.   NATURE IMMUNOLOGY

Citrullination of TNF-α by peptidylarginine deiminases reduces its capacity to stimulate the production of inflammatory chemokines

(2012) Eva A.V. Moelants et al.   CYTOKINE

Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis

(2012) M. A. Moscarello et al.   Disease Models & Mechanisms

Anticancer Peptidylarginine Deiminase (PAD) Inhibitors Regulate the Autophagy Flux and the Mammalian Target of Rapamycin Complex 1 Activity

(2012) Yuji Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor   target gene activation

(2012) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles

(2012) Soi Law et al.   ARTHRITIS RESEARCH & THERAPY

Ca2+ signaling in the regulation of dendritic cell functions

(2011) Ekaterina Shumilina et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor

(2011) Alexander A. Chumanevich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells

(2011) Jamie M. Ireland et al.   JOURNAL OF EXPERIMENTAL MEDICINE

N-α-Benzoyl-N5-(2-Chloro-1-Iminoethyl)-l-Ornithine Amide, a Protein Arginine Deiminase Inhibitor, Reduces the Severity of Murine Collagen-Induced Arthritis

(2011) Van C. Willis et al.   JOURNAL OF IMMUNOLOGY

Contribution of TLR7 and TLR9 signaling to the susceptibility of MyD88-deficient mice to myocarditis

(2010) Philippe P. Pagni et al.   AUTOIMMUNITY

Protein arginine deiminase 4: a target for an epigenetic cancer therapy

(2010) Jessica L. Slack et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

(2010) Pingxin Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Involvement of peptidylarginine deiminase-mediated post-translational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease

(2009) Byungki Jang et al.   ACTA NEUROPATHOLOGICA

Identification of citrullinated vimentin peptides as T cell epitopes in HLA–DR4–positive patients with rheumatoid arthritis

(2009) Anouk L. Feitsma et al.   ARTHRITIS AND RHEUMATISM

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Dendritic cells as targets for therapy in rheumatoid arthritis

(2009) Shaukat Khan et al.   Nature Reviews Rheumatology

Dendritic cells and cytokines in human inflammatory and autoimmune diseases

(2008) P BLANCO et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Constitutive Crosspresentation of Tissue Antigens by Dendritic Cells Controls CD8+ T Cell Tolerance In Vivo

(2008) Nancy Luckashenak et al.   IMMUNITY

Regulation of p53 Target Gene Expression by Peptidylarginine Deiminase 4

(2008) P. Li et al.   MOLECULAR AND CELLULAR BIOLOGY