Anticancer Peptidylarginine Deiminase (PAD) Inhibitors Regulate the Autophagy Flux and the Mammalian Target of Rapamycin Complex 1 Activity
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Anticancer Peptidylarginine Deiminase (PAD) Inhibitors Regulate the Autophagy Flux and the Mammalian Target of Rapamycin Complex 1 Activity
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 31, Pages 25941-25953
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-05-18
DOI
10.1074/jbc.m112.375725
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Introduction to Theme “Chromatin, Epigenetics, and Transcription”
- (2012) Joan W. Conaway Annual Review of Biochemistry
- Cancer epigenomics: beyond genomics
- (2012) Juan Sandoval et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Expression of Peptidylarginine Deiminase Type 4 in Ovarian Tumors
- (2012) Lin Wang et al. International Journal of Biological Sciences
- Investigating the Pathogenic Role of PADI4 in Oesophageal Cancer
- (2012) Xiaotian Chang et al. International Journal of Biological Sciences
- Regulation of histone modification and chromatin structure by the p53–PADI4 pathway
- (2012) Chizu Tanikawa et al. Nature Communications
- Synthesis and Screening of a Haloacetamidine Containing Library To Identify PAD4 Selective Inhibitors
- (2011) Justin E. Jones et al. ACS Chemical Biology
- Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis
- (2011) Erika Darrah et al. ANNALS OF THE RHEUMATIC DISEASES
- Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor
- (2011) Scott R. Daigle et al. CANCER CELL
- BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
- (2011) Jake E. Delmore et al. CELL
- “Misinterpretation” of a histone mark is linked to aberrant stem cells and cancer development
- (2011) Gang G. Wang et al. CELL CYCLE
- Principles and Current Strategies for Targeting Autophagy for Cancer Treatment
- (2011) R. K. Amaravadi et al. CLINICAL CANCER RESEARCH
- Citrullination of Inhibitor of Growth 4 (ING4) by Peptidylarginine Deminase 4 (PAD4) Disrupts the Interaction between ING4 and p53
- (2011) Qin Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Development ofN-α-(2-Carboxyl)benzoyl-N5-(2-fluoro-1-iminoethyl)-l-ornithine Amide (o-F-amidine) andN-α-(2-Carboxyl)benzoyl-N5-(2-chloro-1-iminoethyl)-l-ornithine Amide (o-Cl-amidine) As Second Generation Protein Arginine Deiminase (PAD) Inhibitors
- (2011) Corey P. Causey et al. JOURNAL OF MEDICINAL CHEMISTRY
- RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
- (2011) Johannes Zuber et al. NATURE
- Genome-Wide Analysis Reveals PADI4 Cooperates with Elk-1 to Activate c-Fos Expression in Breast Cancer Cells
- (2011) Xuesen Zhang et al. PLoS Genetics
- Methods in Mammalian Autophagy Research
- (2010) Noboru Mizushima et al. CELL
- Stimulation of autophagy by the p53 target gene Sestrin2
- (2010) Maria Chiara Maiuri et al. CELL CYCLE
- Regulation of mouse oocyte microtubule and organelle dynamics by PADI6 and the cytoplasmic lattices
- (2010) Rui Kan et al. DEVELOPMENTAL BIOLOGY
- PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps
- (2010) Pingxin Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
- {2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acetic acid methyl ester (MIAM): Its anti-cancer efficacy and intercalation mechanism identified via multi-model systems
- (2010) Wenjing Wang et al. Molecular BioSystems
- Autophagy and the Integrated Stress Response
- (2010) Guido Kroemer et al. MOLECULAR CELL
- Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression
- (2010) P Li et al. ONCOGENE
- Increased PADI4 expression in blood and tissues of patients with malignant tumors
- (2009) Xiaotian Chang et al. BMC CANCER
- Regulation of Protein Citrullination through p53/PADI4 Network in DNA Damage Response
- (2009) C. Tanikawa et al. CANCER RESEARCH
- Blinded by the Light: The Growing Complexity of p53
- (2009) Karen H. Vousden et al. CELL
- Modes of p53 Regulation
- (2009) Jan-Philipp Kruse et al. CELL
- Mammalian target of rapamycin complex 1: Signalling inputs, substrates and feedback mechanisms
- (2009) E.A. Dunlop et al. CELLULAR SIGNALLING
- Mammalian autophagy: core molecular machinery and signaling regulation
- (2009) Zhifen Yang et al. CURRENT OPINION IN CELL BIOLOGY
- Two Mammalian MOF Complexes Regulate Transcription Activation by Distinct Mechanisms
- (2009) Xiangzhi Li et al. MOLECULAR CELL
- p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
- (2008) Andrei V. Budanov et al. CELL
- Transcriptional regulation of peptidylarginine deiminase expression in human keratinocytes
- (2008) Shibo Ying et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Neutral loss of isocyanic acid in peptide CID spectra: A novel diagnostic marker for mass spectrometric identification of protein citrullination
- (2008) Gang Hao et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Regulation of p53 Target Gene Expression by Peptidylarginine Deiminase 4
- (2008) P. Li et al. MOLECULAR AND CELLULAR BIOLOGY
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
- An improved synthesis of haloacetamidine-based inactivators of protein arginine deiminase 4 (PAD4)
- (2008) Corey P. Causey et al. TETRAHEDRON LETTERS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More