Technical Advance: Ascorbic acid induces development of double-positive T cells from human hematopoietic stem cells in the absence of stromal cells

Human proT-cells generated in vitro facilitate hematopoietic stem cell-derived T-lymphopoiesis in vivo and restore thymic architecture

(2013) G. Awong et al.   BLOOD

An epigenetic profile of early T-cell development from multipotent progenitors to committed T-cell descendants

(2013) Maria Alessandra Vigano et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T-cell reconstitution after allogeneic stem cell transplantation: assessment by measurement of the sjTREC/ TREC ratio and thymic naive T cells

(2013) S. Ringhoffer et al.   HAEMATOLOGICA

T cell–derived inducible nitric oxide synthase switches off TH17 cell differentiation

(2013) Jianjun Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Generation of Functional, Antigen-Specific CD8+ Human T Cells from Cord Blood Stem Cells Using Exogenous Notch and Tetramer-TCR Signaling

(2013) Irina Fernandez et al.   STEM CELLS

Vitamin C Promotes Maturation of T-Cells

(2012) Jared Manning et al.   ANTIOXIDANTS & REDOX SIGNALING

Dynamic Transformations of Genome-wide Epigenetic Marking and Transcriptional Control Establish T Cell Identity

(2012) Jingli A. Zhang et al.   CELL

Comparative and Functional Evaluation of In Vitro Generated to Ex Vivo CD8 T Cells

(2012) D. D. Dervovic et al.   JOURNAL OF IMMUNOLOGY

Human T-Lymphoid Progenitors Generated in a Feeder-Cell-Free Delta-Like-4 Culture System Promote T-Cell Reconstitution in NOD/SCID/γc−/− Mice

(2012) Christian Reimann et al.   STEM CELLS

Hematopoietic progenitor migration to the adult thymus

(2011) Daniel A. Zlotoff et al.   Annals of the New York Academy of Sciences

Delivery of progenitors to the thymus limits T-lineage reconstitution after bone marrow transplantation

(2011) D. A. Zlotoff et al.   BLOOD

Thymic T-cell development in allogeneic stem cell transplantation

(2011) W. Krenger et al.   BLOOD

Cytokines and culture medium have a major impact on human in vitro T-cell differentiation

(2011) Emmanuelle M. Six et al.   BLOOD CELLS MOLECULES AND DISEASES

T cells fail to develop in the human skin-cell explants system; an inconvenient truth

(2011) Bob Meek et al.   BMC IMMUNOLOGY

The SLC23 family of ascorbate transporters: ensuring that you get and keep your daily dose of vitamin C

(2011) James M May   BRITISH JOURNAL OF PHARMACOLOGY

Pre-differentiated human committed T-lymphoid progenitors promote peripheral T-cell re-constitution after stem cell transplantation in immunodeficient mice

(2011) Matthias Eyrich et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nitric Oxide Modulates TGF- -Directive Signals To Suppress Foxp3+ Regulatory T Cell Differentiation and Potentiate Th1 Development

(2011) S.-W. Lee et al.   JOURNAL OF IMMUNOLOGY

Ascorbic Acid: An Old Player with a Broad Impact on Body Physiology Including Oxidative Stress Suppression and Immunomodulation: A Review

(2011) M. Pohanka et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells

(2010) Miguel Angel Esteban et al.   Cell Stem Cell

Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution

(2010) Colleen Delaney et al.   NATURE MEDICINE

An Essential Developmental Checkpoint for Production of the T Cell Lineage

(2010) T. Ikawa et al.   SCIENCE

Characterization in vitro and engraftment potential in vivo of human progenitor T cells generated from hematopoietic stem cells

(2009) G. Awong et al.   BLOOD

In vitro-differentiated T/natural killer-cell progenitors derived from human CD34+ cells mature in the thymus

(2009) B. Meek et al.   BLOOD

Thymic involution and immune reconstitution

(2009) Heather E. Lynch et al.   TRENDS IN IMMUNOLOGY

Delta-like 4 is indispensable in thymic environment specific for T cell development

(2008) Katsuto Hozumi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment

(2008) Ute Koch et al.   JOURNAL OF EXPERIMENTAL MEDICINE