Human T-Lymphoid Progenitors Generated in a Feeder-Cell-Free Delta-Like-4 Culture System Promote T-Cell Reconstitution in NOD/SCID/γc−/− Mice

Thymic tissue is not evident on high-resolution computed tomography and [18F]Fluoro-deoxy-glucose positron emission tomography scans of aviraemic HIV patients with poor recovery of CD4+ T cells

(2011) Sara Tanaskovic et al.   AIDS

Immune Reconstitution after Double Umbilical Cord Blood Stem Cell Transplantation: Comparison with Unrelated Peripheral Blood Stem Cell Transplantation

(2011) Caron A. Jacobson et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Delivery of progenitors to the thymus limits T-lineage reconstitution after bone marrow transplantation

(2011) D. A. Zlotoff et al.   BLOOD

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions

(2011) I. Van de Walle et al.   BLOOD

Thymic T-cell development in allogeneic stem cell transplantation

(2011) W. Krenger et al.   BLOOD

Cytokines and culture medium have a major impact on human in vitro T-cell differentiation

(2011) Emmanuelle M. Six et al.   BLOOD CELLS MOLECULES AND DISEASES

Pre-differentiated human committed T-lymphoid progenitors promote peripheral T-cell re-constitution after stem cell transplantation in immunodeficient mice

(2011) Matthias Eyrich et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells

(2011) Barbara Varnum-Finney et al.   JOURNAL OF CLINICAL INVESTIGATION

Outcomes, infections, and immune reconstitution after double cord blood transplantation in patients with high-risk hematological diseases

(2011) A. Ruggeri et al.   Transplant Infectious Disease

Direct Comparison of Dll1- and Dll4-Mediated Notch Activation Levels Shows Differential Lymphomyeloid Lineage Commitment Outcomes

(2010) M. Mohtashami et al.   JOURNAL OF IMMUNOLOGY

Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution

(2010) Colleen Delaney et al.   NATURE MEDICINE

Reprogramming of T Cells to Natural Killer-Like Cells upon Bcl11b Deletion

(2010) P. Li et al.   SCIENCE

An Early T Cell Lineage Commitment Checkpoint Dependent on the Transcription Factor Bcl11b

(2010) L. Li et al.   SCIENCE

An Essential Developmental Checkpoint for Production of the T Cell Lineage

(2010) T. Ikawa et al.   SCIENCE

Notch regulation of early thymocyte development

(2010) Yumi Yashiro-Ohtani et al.   SEMINARS IN IMMUNOLOGY

Stromal cell-derived factor 1α and CXCR4: newly defined requirements for efficient thymic β-selection

(2010) Michelle L. Janas et al.   TRENDS IN IMMUNOLOGY

Characterization in vitro and engraftment potential in vivo of human progenitor T cells generated from hematopoietic stem cells

(2009) G. Awong et al.   BLOOD

In vitro-differentiated T/natural killer-cell progenitors derived from human CD34+ cells mature in the thymus

(2009) B. Meek et al.   BLOOD

Thymic development beyond β-selection requires phosphatidylinositol 3-kinase activation by CXCR4

(2009) Michelle L. Janas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia

(2009) Sara González-García et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Notch Activation Induces the Generation of Functional NK Cells from Human Cord Blood CD34-Positive Cells Devoid of IL-15

(2009) Kyoko Haraguchi et al.   JOURNAL OF IMMUNOLOGY

Delta-like 4 is indispensable in thymic environment specific for T cell development

(2008) Katsuto Hozumi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment

(2008) Ute Koch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors

(2008) Johannes L Zakrzewski et al.   NATURE BIOTECHNOLOGY

Reconstitution of the immune system after hematopoietic stem cell transplantation in humans

(2008) Jan Storek et al.   Seminars in Immunopathology