Secreted virulence factors and immune evasion in visceral leishmaniasis

Exosomes and Cancer: A Newly Described Pathway of Immune Suppression

(2011) H.-G. Zhang et al.   CLINICAL CANCER RESEARCH

Human cutaneous leishmaniasis: interferon-dependent expression of double-stranded RNA-dependent protein kinase (PKR) via TLR2

(2011) Áislan de Carvalho Vivarini et al.   FASEB JOURNAL

Myeloid Cell IL-10 Production in Response to Leishmania Involves Inactivation of Glycogen Synthase Kinase-3  Downstream of Phosphatidylinositol-3 Kinase

(2011) D. Nandan et al.   JOURNAL OF IMMUNOLOGY

mTOR signaling pathway regulates the IL-12/IL-10 axis in Leishmania donovani infection

(2011) Satyanarayana Swamy Cheekatla et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Temperature-Induced Protein Secretion by Leishmania mexicana Modulates Macrophage Signalling and Function

(2011) Kasra Hassani et al.   PLoS One

Exosomes and other microvesicles in infection biology: organelles with unanticipated phenotypes

(2010) Judith Maxwell Silverman et al.   CELLULAR MICROBIOLOGY

Leishmania infantum chagasi: A genome-based approach to identification of excreted/secreted proteins

(2010) Sruti DebRoy et al.   EXPERIMENTAL PARASITOLOGY

Leishmania donovani Amastigotes Impair Gamma Interferon-Induced STAT1  Nuclear Translocation by Blocking the Interaction between STAT1  and Importin- 5

(2010) C. Matte et al.   INFECTION AND IMMUNITY

Chlamydia muridarum T-Cell Antigens Formulated with the Adjuvant DDA/TDB Induce Immunity against Infection That Correlates with a High Frequency of Gamma Interferon (IFN- )/Tumor Necrosis Factor Alpha and IFN- /Interleukin-17 Double-Positive CD4+ T Cells

(2010) H. Yu et al.   INFECTION AND IMMUNITY

An Experimental Approach for the Identification of Conserved Secreted Proteins in Trypanosomatids

(2010) Rosa M. Corrales et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages

(2010) Judith Maxwell Silverman et al.   JOURNAL OF CELL SCIENCE

The p110  Isoform of Phosphatidylinositol 3-Kinase Controls the Quality of Secondary Anti-Leishmania Immunity by Regulating Expansion and Effector Function of Memory T Cell Subsets

(2010) D. Liu et al.   JOURNAL OF IMMUNOLOGY

Leishmania Exosomes Modulate Innate and Adaptive Immune Responses through Effects on Monocytes and Dendritic Cells

(2010) J. M. Silverman et al.   JOURNAL OF IMMUNOLOGY

Schistosomal‐Derived Lysophosphatidylcholine Are Involved in Eosinophil Activation and Recruitment through Toll‐Like Receptor–2–Dependent Mechanisms

(2010) Kelly G. Magalhães et al.   JOURNAL OF INFECTIOUS DISEASES

MAPK-directed phosphatases preferentially regulate pro- and anti-inflammatory cytokines in experimental visceral leishmaniasis: involvement of distinct protein kinase C isoforms

(2010) Susanta Kar et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Exosomes: Extracellular organelles important in intercellular communication

(2010) Suresh Mathivanan et al.   Journal of Proteomics

Localization and induction of the A2 virulence factor in Leishmania: evidence that A2 is a stress response protein

(2010) Laura-Isobel McCall et al.   MOLECULAR MICROBIOLOGY

Fragments of antigen-loaded dendritic cells (DC) and DC-derived exosomes induce protective immunity against Leishmania major

(2010) Johannes K. Schnitzer et al.   VACCINE

Leishmania-Induced Inactivation of the Macrophage Transcription Factor AP-1 Is Mediated by the Parasite Metalloprotease GP63

(2010) Irazú Contreras et al.   PLoS Pathogens

Novel role for the double-stranded RNA-activated protein kinase PKR: modulation of macrophage infection by the protozoan parasite Leishmania

(2009) Renata M. S. Pereira et al.   FASEB JOURNAL

Major Surface Protease of Trypanosomatids: One Size Fits All?

(2009) C. Yao   INFECTION AND IMMUNITY

Tuberculosis Subunit Vaccination Provides Long-Term Protective Immunity Characterized by Multifunctional CD4 Memory T Cells

(2009) T. Lindenstrom et al.   JOURNAL OF IMMUNOLOGY

The p110  Isoform of Phosphatidylinositol 3-Kinase Controls Susceptibility to Leishmania major by Regulating Expansion and Tissue Homing of Regulatory T Cells

(2009) D. Liu et al.   JOURNAL OF IMMUNOLOGY

Proteomic characterization of the released/secreted proteins of Leishmania (Viannia) braziliensis promastigotes

(2009) Patricia Cuervo et al.   Journal of Proteomics

Leishmania GP63 Alters Host Signaling Through Cleavage-Activated Protein Tyrosine Phosphatases

(2009) M. A. Gomez et al.   Science Signaling

Exosomes are an effective vaccine against congenital toxoplasmosis in mice

(2009) Céline Beauvillain et al.   VACCINE

Secretome: clues into pathogen infection and clinical applications

(2009) Shoba Ranganathan et al.   Genome Medicine

Vector Transmission of Leishmania Abrogates Vaccine-Induced Protective Immunity

(2009) Nathan C. Peters et al.   PLoS Pathogens

Unconventional Mechanisms of Protein Transport to the Cell Surface of Eukaryotic Cells

(2008) Walter Nickel et al.   Annual Review of Cell and Developmental Biology

Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells

(2008) M. Ohtani et al.   BLOOD

Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation

(2008) T. Lieke et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Effective clearance of intracellularLeishmania majorin vivo requires Pten in macrophages

(2008) Shoko Kuroda et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A novel form of NF-κB is induced byLeishmaniainfection: Involvement in macrophage gene expression

(2008) David J. Gregory et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Leishmania major intracellular survival is not altered in SHP-1 deficient mev or CD45−/− mice

(2008) Gerald F. Späth et al.   EXPERIMENTAL PARASITOLOGY

Activation of PI3K/Akt signaling has a dominant negative effect on IL-12 production by macrophages infected with Leishmania amazonensis promastigotes

(2008) Aaron Ruhland et al.   EXPERIMENTAL PARASITOLOGY

Regulation of macrophage nitric oxide production by the protein tyrosine phosphatase Src homology 2 domain phosphotyrosine phosphatase 1 (SHP-1)

(2008) Julie Blanchette et al.   IMMUNOLOGY

Fibronectin Binding and Proteolytic Degradation by Leishmania and Effects on Macrophage Activation

(2008) M. M. Kulkarni et al.   INFECTION AND IMMUNITY

TheLeishmaniaSurface Protease GP63 Cleaves Multiple Intracellular Proteins and Actively Participates in p38 Mitogen-activated Protein Kinase Inactivation

(2008) Maxime Hallé et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE

Proteomic analysis of the secretome of Leishmania donovani

(2008) J Maxwell Silverman et al.   GENOME BIOLOGY