The potential of carbon-11 and fluorine-18 chemistry: illustration through the development of positron emission tomography radioligands targeting the translocator protein 18 kDa

[11C]Phosgene: A Versatile Reagent for Radioactive Carbonyl Insertion Into Medicinal Radiotracers for Positron Emission Tomography

(2012) Dirk Roeda et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The translocator protein ligand [18F]DPA-714 images glioma and activated microglia in vivo

(2012) Alexandra Winkeler et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Noninvasive Molecular Imaging of Neuroinflammation

(2012) Andreas H Jacobs et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Imaging Microglial/Macrophage Activation in Spinal Cords of Experimental Autoimmune Encephalomyelitis Rats by Positron Emission Tomography Using the Mitochondrial 18 kDa Translocator Protein Radioligand [18F]DPA-714

(2012) G. Abourbeh et al.   JOURNAL OF NEUROSCIENCE

Reactive Astrocytes Overexpress TSPO and Are Detected by TSPO Positron Emission Tomography Imaging

(2012) S. Lavisse et al.   JOURNAL OF NEUROSCIENCE

[18F]DPA-714, [18F]PBR111 and [18F]FEDAA1106—Selective radioligands for imaging TSPO 18kDa with PET: Automated radiosynthesis on a TRACERLAb FX-FN synthesizer and quality controls

(2011) Bertrand Kuhnast et al.   APPLIED RADIATION AND ISOTOPES

Synthesis of 6-[18F]fluoro-PBR28, a novel radiotracer for imaging the TSPO 18kDa with PET

(2011) Annelaure Damont et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of fluorine-18-labelled TSPO ligands for imaging neuroinflammation with Positron Emission Tomography

(2011) Dirk Roeda et al.   JOURNAL OF FLUORINE CHEMISTRY

The Translocator Protein

(2011) A. M. Scarf et al.   JOURNAL OF NUCLEAR MEDICINE

Differential Expression of the 18 kDa Translocator Protein (TSPO) by Neoplastic and Inflammatory Cells in Mouse Tumors of Breast Cancer

(2011) Jinzi Zheng et al.   MOLECULAR PHARMACEUTICS

In vivo imaging of neuroinflammation in the rodent brain with [11C]SSR180575, a novel indoleacetamide radioligand of the translocator protein (18 kDa)

(2010) Fabien Chauveau et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

In vivo imaging of neuroinflammation: a comparative study between [18F]PBR111, [11C]CLINME and [11C]PK11195 in an acute rodent model

(2010) Nadja Van Camp et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Molecular targets: Inflammation & metabolic disease posters

(2010)   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Radiosynthesis of 7-chloro-N,N-dimethyl-5-[11C]methyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, [11C]SSR180575, a novel radioligand for imaging the TSPO (peripheral benzodiazepine receptor) with PET

(2010) Cyrille Thominiaux et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Reduced PBR/TSPO Expression After Minocycline Treatment in a Rat Model of Focal Cerebral Ischemia: A PET Study Using [18F]DPA-714

(2010) Abraham Martín et al.   MOLECULAR IMAGING AND BIOLOGY

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

(2010) Rainer Rupprecht et al.   NATURE REVIEWS DRUG DISCOVERY

[18F]FEAC and [18F]FEDAC: Two novel positron emission tomography ligands for peripheral-type benzodiazepine receptor in the brain

(2009) Kazuhiko Yanamoto et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Fully automated synthesis and initial PET evaluation of [11C]PBR28

(2009) Min Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Radiolabelled Molecules for Imaging the Translocator Protein (18 kDa) Using Positron Emission Tomography

(2009) Frederic Dolle et al.   CURRENT MEDICINAL CHEMISTRY

Evaluation of the PBR/TSPO Radioligand [18F]DPA-714 in a Rat Model of Focal Cerebral Ischemia

(2009) Abraham Martín et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Translocator Protein (18 kDa): Central Nervous System Disease and Drug Design

(2009) Alana M. Scarf et al.   JOURNAL OF MEDICINAL CHEMISTRY

Single-Step High-Yield Radiosynthesis and Evaluation of a Sensitive18F-Labeled Ligand for Imaging Brain Peripheral Benzodiazepine Receptors with PET

(2009) Emmanuelle Briard et al.   JOURNAL OF MEDICINAL CHEMISTRY

Radioisotopic Imaging of Neuroinflammation

(2009) A. Winkeler et al.   JOURNAL OF NUCLEAR MEDICINE

Comparative Evaluation of the Translocator Protein Radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a Rat Model of Acute Neuroinflammation

(2009) F. Chauveau et al.   JOURNAL OF NUCLEAR MEDICINE

A simplified [11C]phosgene synthesis

(2009) Yann Bramoullé et al.   TETRAHEDRON LETTERS

Uptake of inflammatory cell marker [11C]PK11195 into mouse atherosclerotic plaques

(2008) Iina Laitinen et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers

(2008) Fabien Chauveau et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Radiosynthesis of [18F]DPA‐714, a selective radioligand for imaging the translocator protein (18 kDa) with PET

(2008) Annelaure Damont et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Radiosynthesis of [18F]PBR111, a selective radioligand for imaging the translocator protein (18 kDa) with PET

(2008) Frédéric Dollé et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Synthesis and Biological Evaluation of Substituted [18F]Imidazo[1,2-a]pyridines and [18F]Pyrazolo[1,5-a]pyrimidines for the Study of the Peripheral Benzodiazepine Receptor Using Positron Emission Tomography

(2008) Christopher J. R. Fookes et al.   JOURNAL OF MEDICINAL CHEMISTRY

DPA-714, a New Translocator Protein-Specific Ligand: Synthesis, Radiofluorination, and Pharmacologic Characterization

(2008) M. L. James et al.   JOURNAL OF NUCLEAR MEDICINE

Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors

(2008) Alan A. Wilson et al.   NUCLEAR MEDICINE AND BIOLOGY

Synthesis and Evaluation in Monkey of Two Sensitive11C-Labeled Aryloxyanilide Ligands for Imaging Brain Peripheral Benzodiazepine Receptors In Vivo

(2007) Emmanuelle Briard et al.   JOURNAL OF MEDICINAL CHEMISTRY