Article
Geriatrics & Gerontology
Wentao Lin, Chaoqin He, Faqin Xie, Tao Chen, Guanghao Zheng, Houjie Yin, Haixiong Chen, Zhiyun Wang
Summary: In this study, the authors assessed the diagnostic discordance between lumbar osteoporosis detected by QCT and DXA, and evaluated their predictive performance for prevalent vertebral fracture. The results showed that in older patients undergoing spinal surgery, QCT-vBMD is more helpful than DXA in terms of osteoporosis detection rate and prediction of patients with prevalent VFs.
Review
Endocrinology & Metabolism
Dilki Madhuchani, Sumudu Nimali Seneviratne, Leanne M. Ward
Summary: Bone accrual in childhood affects bone health later in life. Early loss of bone strength can lead to health issues and lower quality of life in childhood and adolescence. Improved assessment tools and treatment options, along with awareness of fracture history and risk factors, have enhanced the detection and management of bone fragility in children globally.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Obstetrics & Gynecology
S. Cerdas Perez, L. E. Herrera, E. Gonzalez
Summary: Osteoporosis is a prevalent skeletal disorder that decreases bone strength and increases the risk of fragility fractures. Dual-energy X-ray absorptiometry (DXA) is the preferred method for evaluating bone mineral density, but clinical and technical considerations must be taken into account to avoid misdiagnosis.
Review
Endocrinology & Metabolism
Joanna Heuchert, Slawomir Koziel, Anna E. Spinek
Summary: This review evaluates the accuracy of various mandibular radiomorphometric indices in comparison with DEXA BMD measurements for diagnosing osteopenia and osteoporosis. The study found that these indices can be useful as a screening tool, but not for diagnosis.
OSTEOPOROSIS INTERNATIONAL
(2023)
Article
Gastroenterology & Hepatology
Jia-Liang Chen, Yao Liu, Yu-Fei Bi, Xian-Bo Wang
Summary: This study assessed the prevalence and clinical characteristics of osteoporosis in Chinese patients with PBC. The results showed that osteoporosis is very common in PBC patients, with older age, lower BMI, previous steroid therapy, and advanced liver disease being the main independent risk factors.
WORLD JOURNAL OF GASTROENTEROLOGY
(2023)
Review
Endocrinology & Metabolism
Mel Mupparapu, Sunday O. Akintoye
Summary: This review presents the advances in the practical application of dental panoramic radiography (DPR) for predicting early onset of osteopenia and osteoporosis. The evaluation of the inferior border of the mandible and the trabecular bone within the mandible can help identify early signs of osteopenia and patients at risk for osteoporosis.
CURRENT OSTEOPOROSIS REPORTS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ferdinand Roski, Johannes Hammel, Kai Mei, Bernhard Haller, Thomas Baum, Jan S. Kirschke, Daniela Pfeiffer, Klaus Woertler, Franz Pfeiffer, Peter B. Noel, Alexandra S. Gersing, Benedikt J. Schwaiger
Summary: The study assessed the diagnostic accuracy of iodine-corrected vertebral BMD measurements derived from non-dedicated contrast-enhanced phantomless dual-layer spectral CT examinations. Converted BMD values adjusted for individual vessel iodine concentrations showed a high agreement with non-enhanced DLCT-BMD, suggesting that opportunistic BMD measurements are feasible even in non-dedicated contrast-enhanced DLCT examinations.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Andre Euler, Tristan Nowak, Brian Bucher, Matthias Eberhard, Bernhard Schmidt, Thomas G. Flohr, Diana Frey, Oliver Distler, Hatem Alkadhi
Summary: The study assessed the accuracy and impact of different sizes and tube voltages on bone mineral density (BMD) using a photon-counting detector CT system in an ex vivo animal spine. Results showed that neither size nor tube voltage had significant effect on BMD measurements.
INVESTIGATIVE RADIOLOGY
(2021)
Article
Genetics & Heredity
M. Mouille, M. Rio, S. Breton, M. L. Piketty, A. Afenjar, J. Amiel, Y. Capri, A. Goldenberg, C. Francannet, C. Michot, C. Mignot, L. Perrin, C. Quelin, J. Van Gils, G. Barcia, V Pingault, G. Maruani, E. Koumakis, V Cormier-Daire
Summary: This study systematically reviewed the skeletal manifestations of SATB2-associated syndrome and found that pathogenic variants in SATB2 are responsible for skeletal demineralization and osteoporosis. The study also discovered increased levels of bone formation markers, supporting the key role of SATB2 in osteoblast differentiation. Therefore, bone evaluation is recommended for children and adult patients with SATB2-associated syndrome.
ORPHANET JOURNAL OF RARE DISEASES
(2022)
Review
Medicine, General & Internal
Fabio Massimo Ulivieri, Luca Rinaudo
Summary: A proper assessment of osteoporotic fragility fracture prediction requires consideration of factors like bone density, texture, geometry, and strength, obtained through methods like dual X-ray absorptiometry (DXA). The Bone Strain Index (BSI) is a new DXA-derived index designed to evaluate bone resistance to strain by incorporating information on density distribution, bone geometry, and loadings.
FRONTIERS IN MEDICINE
(2021)
Article
Chemistry, Multidisciplinary
Junjie Li, Ruizhi Zhang, Yawei Du, Gongwen Liu, Yu Dong, Miao Zheng, Wenguo Cui, Peng Jia, Youjia Xu
Summary: Osteoclast adhesion and bone resorption are the main causes of postmenopausal osteoporosis (PMOP). Hsa-miR-378i/mmu-miR-378a-3p has been identified as closely associated with PMOP. An osteophilic and dual-regulated antagomir@Aln-Lipo has been developed to effectively reverse bone loss by synergistically regulating osteoclastogenesis and bone resorption.
Article
Nutrition & Dietetics
Inge A. L. P. van Beijsterveldt, Manouk van der Steen, Kirsten S. de Fluiter, Sander A. M. J. Spaans, Anita C. S. Hokken-Koelega
Summary: Childhood obesity is a global public health threat, and this study provides sex-specific reference values and charts for body composition and bone mineral density in children aged 2-5 years.
CLINICAL NUTRITION
(2022)
Article
Clinical Neurology
Wentao Lin, Chaoqin He, Faqin Xie, Tao Chen, Guanghao Zheng, Houjie Yin, Haixiong Chen, Zhiyun Wang
Summary: This study compared the diagnostic accuracy of quantitative computed tomography (QCT) and dual-energy X-ray absorptiometry (DXA) in detecting lumbar osteoporosis, and found that QCT provided more accurate evaluation of bone density than DXA. QCT measurements at specific vertebral levels showed high diagnostic performance for osteoporotic vertebral compression fractures (OVCF).
Article
Agriculture, Dairy & Animal Science
C. Kasper, P. Schlegel, I. Ruiz-Ascacibar, P. Stoll, G. Bee
Summary: Studies in animal science show that DXA measurements may not perfectly match dissections or chemical analyses, requiring calibration equations. Predictions related to body composition and single nutrient content in pigs show promising results, with potential for creating generic regression equations that yield reliable estimates. DXA could be a useful tool for high-throughput phenotyping in genetic studies, efficiently measuring body composition in a wide range of animals.
Article
Gastroenterology & Hepatology
Phil A. Hart, Dhiraj Yadav, Liang Li, Savi Appana, William Fisher, Evan Fogel, Chris E. Forsmark, Walter G. Park, Stephen Pandol, Mark D. Topazian, Stephen K. Van den Eden, Santhi Swaroop Vege, David Bradley, Jose Serrano, Darwin L. Conwell
Summary: Chronic pancreatitis patients have a high prevalence of osteopathy, with older age, female sex, white race, and underweight body mass index category being associated with a higher probability of osteopathy.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)