The path of malaria vaccine development: challenges and perspectives

A Microscale Human Liver Platform that Supports the Hepatic Stages of Plasmodium falciparum and vivax

(2013) Sandra March et al.   Cell Host & Microbe

Single-Dose Microparticle Delivery of a Malaria Transmission- Blocking Vaccine Elicits a Long-Lasting Functional Antibody Response

(2013) R.R. Dinglasan et al.   CURRENT MOLECULAR MEDICINE

Combination of adjuvants: the future of vaccine design

(2013) Adele Mount et al.   Expert Review of Vaccines

RALP1 Is a Rhoptry Neck Erythrocyte-Binding Protein of Plasmodium falciparum Merozoites and a Potential Blood-Stage Vaccine Candidate Antigen

(2013) Daisuke Ito et al.   INFECTION AND IMMUNITY

The Malaria Vaccine Candidate GMZ2 Elicits Functional Antibodies in Individuals From Malaria Endemic and Non-Endemic Areas

(2013) Micha Phill Grønholm Jepsen, Prajakta S. Jogdand, Susheel K. Singh, Meral Esen, Michael Christiansen, Saadou Issifou, Aurore B. Hounkpatin, Ulysse Ateba-Ngoa, Peter G. Kremsner, Morten H. Dziegiel, Severin Olesen-Larsen et al.   JOURNAL OF INFECTIOUS DISEASES

Phase 1b Randomized Trial and Follow-Up Study in Uganda of the Blood-Stage Malaria Vaccine Candidate BK-SE36

(2013) Nirianne Marie Q. Palacpac et al.   PLoS One

Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity

(2013) E. M. Bijker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine

(2013) R. A. Seder et al.   SCIENCE

Development of a Pfs25-EPA malaria transmission blocking vaccine as a chemically conjugated nanoparticle

(2013) Richard L. Shimp et al.   VACCINE

Bacillus Calmette-Guerin (BCG) immunotherapy for bladder cancer: Current understanding and perspectives on engineered BCG vaccine

(2012) Koji Kawai et al.   CANCER SCIENCE

Malaria vaccine development: persistent challenges

(2012) Ashley M Vaughan et al.   CURRENT OPINION IN IMMUNOLOGY

Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study

(2012) Chanaki Amaratunga et al.   LANCET INFECTIOUS DISEASES

MALVAC 2012 scientific forum: accelerating development of second-generation malaria vaccines

(2012) Kirsten S Vannice et al.   MALARIA JOURNAL

A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

Heterologous prime-boost regimen adenovector 35-circumsporozoite protein vaccine/recombinant Bacillus Calmette-Guérin expressing the Plasmodium falciparum circumsporozoite induces enhanced long-term memory immunity in BALB/c mice

(2012) Charles Arama et al.   VACCINE

A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants

(2012) Leyla Y. Bustamante et al.   VACCINE

Superior Antimalarial Immunity after Vaccination with Late Liver Stage-Arresting Genetically Attenuated Parasites

(2011) Noah S. Butler et al.   Cell Host & Microbe

Trends in vaccine adjuvants

(2011) Virgil EJC Schijns et al.   Expert Review of Vaccines

Cell biology and immunology of malaria

(2011) Julius Clemence Hafalla et al.   IMMUNOLOGICAL REVIEWS

Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study

(2011) Meta Roestenberg et al.   LANCET

Vaccines against malaria

(2011) A. V. S. Hill   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Rodent blood-stage Plasmodium survive in dendritic cells that infect naive mice

(2011) M. N. Wykes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting TLRs Expands the Antibody Repertoire in Response to a Malaria Vaccine

(2011) S. R. Wiley et al.   Science Translational Medicine

The case for a subunit vaccine against malaria

(2011) Robin F. Anders   TRENDS IN PARASITOLOGY

Comparative efficacy of pre-erythrocytic whole organism vaccine strategies against the malaria parasite

(2011) Johannes Friesen et al.   VACCINE

Cellular and humoral immune effector mechanisms required for sterile protection against sporozoite challenge induced with the novel malaria vaccine candidate CelTOS

(2011) Elke S. Bergmann-Leitner et al.   VACCINE

A recombinant Bacille Calmette–Guérin construct expressing the Plasmodium falciparum circumsporozoite protein enhances dendritic cell activation and primes for circumsporozoite-specific memory cells in BALB/c mice

(2011) Charles Arama et al.   VACCINE

The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

(2011) Alexander D. Douglas et al.   Nature Communications

Sex and Death: The Effects of Innate Immune Factors on the Sexual Reproduction of Malaria Parasites

(2011) Ricardo S. Ramiro et al.   PLoS Pathogens

Safety and Immunogenicity of a Recombinant Nonglycosylated Erythrocyte Binding Antigen 175 Region II Malaria Vaccine in Healthy Adults Living in an Area Where Malaria Is Not Endemic

(2010) H. M. El Sahly et al.   Clinical and Vaccine Immunology

New adjuvants for human vaccines

(2010) M Lamine Mbow et al.   CURRENT OPINION IN IMMUNOLOGY

Combination adjuvants: the next generation of adjuvants?

(2010) George Mutwiri et al.   Expert Review of Vaccines

Molecular vaccines for malaria

(2010) Joseph T. Bruder et al.   Human vaccines & immunotherapeutics

Prime-boost vectored malaria vaccines: Progress and prospects

(2010) Adrian V. S. Hill et al.   Human vaccines & immunotherapeutics

From Vaccines to Memory and Back

(2010) Federica Sallusto et al.   IMMUNITY

Toll-like Receptor 4 Signaling by Follicular Dendritic Cells Is Pivotal for Germinal Center Onset and Affinity Maturation

(2010) Alexandre Garin et al.   IMMUNITY

Advances and challenges in malaria vaccine development

(2010) Peter D. Crompton et al.   JOURNAL OF CLINICAL INVESTIGATION

Evidences of protection against blood-stage infection of Plasmodium falciparum by the novel protein vaccine SE36

(2010) Toshihiro Horii et al.   PARASITOLOGY INTERNATIONAL

Phase 1 Trial of the Plasmodium falciparum Blood Stage Vaccine MSP142-C1/Alhydrogel with and without CPG 7909 in Malaria Naïve Adults

(2010) Ruth D. Ellis et al.   PLoS One

Stress, drugs and the evolution of reproductive restraint in malaria parasites

(2010) S. E. Reece et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Selection Landscape of Malaria Parasites

(2010) M. J. Mackinnon et al.   SCIENCE

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protection against a Malaria Challenge by Sporozoite Inoculation

(2009) Meta Roestenberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adjuvants for malaria vaccines

(2009) R. N. COLER et al.   PARASITE IMMUNOLOGY

Genetic diversity and malaria vaccine design, testing and efficacy: preventing and overcoming ‘vaccine resistant malaria’

(2009) S. L. TAKALA et al.   PARASITE IMMUNOLOGY

Blood Stage Malaria Vaccine Eliciting High Antigen-Specific Antibody Concentrations Confers No Protection to Young Children in Western Kenya

(2009) Bernhards R. Ogutu et al.   PLoS One

Insights into Long-Lasting Protection Induced by RTS,S/AS02A Malaria Vaccine: Further Results from a Phase IIb Trial in Mozambican Children

(2009) Caterina Guinovart et al.   PLoS One

Extreme Polymorphism in a Vaccine Antigen and Risk of Clinical Malaria: Implications for Vaccine Development

(2009) S. L. Takala et al.   Science Translational Medicine

A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali

(2009) Issaka Sagara et al.   VACCINE

A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel®+CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults

(2009) Issaka Sagara et al.   VACCINE

Safety and immunogenicity of GMZ2 — a MSP3–GLURP fusion protein malaria vaccine candidate

(2009) Meral Esen et al.   VACCINE

New horizons in adjuvants for vaccine development

(2008) Steven G. Reed et al.   TRENDS IN IMMUNOLOGY

A Phase 1 trial of PfCP2.9: An AMA1/MSP1 chimeric recombinant protein vaccine for Plasmodium falciparum malaria

(2008) Elissa Malkin et al.   VACCINE