US and European severe asthma cohorts: what can they teach us about severe asthma?

Omalizumab in Severe Allergic Asthma Inadequately Controlled With Standard Therapy

(2013) Nicola A. Hanania et al.   ANNALS OF INTERNAL MEDICINE

Pediatric severe asthma is characterized by eosinophilia and remodeling without TH2 cytokines

(2012) Cara J. Bossley et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Severe Asthma

(2011) Nizar N. Jarjour et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pharmacological treatment of severe, therapy-resistant asthma in children: what can we learn from where?

(2011) A. Bush et al.   EUROPEAN RESPIRATORY JOURNAL

Lung imaging in asthmatic patients: The picture is clearer

(2011) Mario Castro et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma exacerbations: Origin, effect, and prevention

(2011) David J. Jackson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lebrikizumab Treatment in Adults with Asthma

(2011) Jonathan Corren et al.   NEW ENGLAND JOURNAL OF MEDICINE

Detrimental Effects of Environmental Tobacco Smoke in Relation to Asthma Severity

(2011) Suzy A. A. Comhair et al.   PLoS One

Associations between fluctuations in lung function and asthma control in two populations with differing asthma severity

(2011) C. Thamrin et al.   THORAX

Reduction of asthma burden is possible through National Asthma Plans

(2010) M. Kupczyk et al.   ALLERGY

Mast Cell Phenotype, Location, and Activation in Severe Asthma

(2010) Silvana Balzar et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

An Integrative Systems Biology Approach to Understanding Pulmonary Diseases

(2010) Charles Auffray et al.   CHEST

Problematic severe asthma in children, not one problem but many: a GA2LEN initiative

(2010) G. Hedlin et al.   EUROPEAN RESPIRATORY JOURNAL

Racial differences in biologic predictors of severe asthma: Data from the Severe Asthma Research Program

(2010) Christy Gamble et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The molecular phenotype of severe asthma in children

(2010) Anne M. Fitzpatrick et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The role of viruses in acute exacerbations of asthma

(2010) David J. Jackson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes

(2010) Annette T. Hastie et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions

(2010) Xingnan Li et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma

(2010) Jean Bousquet et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Problematic severe asthma: A proposed approach to identifying children who are severely resistant to therapy

(2010) Jon R. Konradsen et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI)

(2010) E. H. Bel et al.   THORAX

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

An Official American Thoracic Society/European Respiratory Society Statement: Asthma Control and Exacerbations

(2009) Helen K. Reddel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Identification of Asthma Phenotypes Using Cluster Analysis in the Severe Asthma Research Program

(2009) Wendy C. Moore et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Recent asthma exacerbations predict future exacerbations in children with severe or difficult-to-treat asthma

(2009) Tmirah Haselkorn et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma

(2009) Pranabashis Haldar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mepolizumab for Prednisone-Dependent Asthma with Sputum Eosinophilia

(2009) Parameswaran Nair et al.   NEW ENGLAND JOURNAL OF MEDICINE

Managing Childhood Asthma: Challenge of Preventing Exacerbations

(2009) Fernando D. Martinez   PEDIATRICS

Cluster Analysis and Clinical Asthma Phenotypes

(2008) Pranab Haldar et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Airway Lipoxin A4Generation and Lipoxin A4Receptor Expression Are Decreased in Severe Asthma

(2008) Anna Planagumà et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Molecular phenotyping of severe asthma using pattern recognition of bronchoalveolar lavage–derived cytokines

(2008) Allan R. Brasier et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Repeatability of response to asthma medications

(2008) Ann Chen Wu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation

(2007) Ronald L. Sorkness et al.   JOURNAL OF APPLIED PHYSIOLOGY