Review
Microbiology
Michael Nel, Zoe Franckling-Smith, Tanyia Pillay, Savvas Andronikou, Heather J. Zar
Summary: Diagnosing pulmonary tuberculosis in children is challenging due to difficulties in obtaining suitable specimens and limitations of current diagnostic methods. Chest imaging plays a crucial role in diagnosis and treatment response monitoring, but traditional chest radiographs are often nonspecific with high inter- and intra-observer variability. Other diagnostic imaging modalities can provide additional information to support diagnosis.
Article
Cardiac & Cardiovascular Systems
Kevin R. An, Charles de Mestral, Derrick Y. Tam, Feng Qiu, Maral Ouzounian, Thomas F. Lindsay, Harindra C. Wijeysundera, Jennifer C-Y Chung
Summary: This study found poor adherence to guideline-directed imaging surveillance following ATAAD repair, while long-term mortality and reinterventions rates remained high. Further research is needed to determine if guidelines should be modified.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jiahui Zhang, Yongye Chen, Xiaoying Xing, Qizheng Wang, Ke Liu, Enlong Zhang, Ning Lang
Summary: This study investigated the imaging manifestations and clinicopathological findings of primary leiomyosarcoma of the spine, finding that the most common clinical symptom is focal pain. Imaging features include solitary tumor lesions, lobulated masses with osteolytic bone destruction and ill-defined borders. The tumor and spinal cord appear isointense on T1WI and T2WI, with contrast-enhanced scanning showing homogeneous enhancement. The study found that the lesion tends not to recur after complete tumor resection.
INSIGHTS INTO IMAGING
(2022)
Article
Chemistry, Multidisciplinary
Jing Zhu, Shuai Ming, Jian Li, Xin Li, Zilan Zhu, Mengxiang Wu, Xinyu Wang, Wei Wei, Karna Ramachandraiah, Fei Ke
Summary: In this study, radiolabeled nanorods were synthesized through a one-pot solvothermal process and transferred to a water solution. The radiolabeled nanorods exhibited excellent colloidal stability and exceptional imaging performance, highlighting their potential use in multimodal imaging.
Article
Rheumatology
Sevtap Tugce Ulas, Felix Radny, Katharina Ziegeler, Iris Eshed, Juliane Greese, Dominik Deppe, Carsten Stelbrink, Robert Biesen, Hildrun Haibel, Valeria Rios Rodriguez, Judith Rademacher, Mikhail Protopopov, Fabian Proft, Denis Poddubnyy, Torsten Diekhoff
Summary: This study aimed to investigate whether self-reported diagnostic confidence can predict diagnostic accuracy in axial spondyloarthritis imaging. The results showed significant differences in diagnostic confidence between correct and incorrect responses for all imaging modalities, and self-reported diagnostic confidence can serve as useful information to predict diagnostic reliability.
Review
Health Care Sciences & Services
Igino Simonetti, Piero Trovato, Vincenza Granata, Carmine Picone, Roberta Fusco, Sergio Venanzio Setola, Mauro Mattace Raso, Corrado Caraco, Paolo A. Ascierto, Fabio Sandomenico, Antonella Petrillo
Summary: Interval metastasis is a specific type of lymph node metastasis in patients with melanoma. Imaging techniques such as ultrasound, CT, MRI, lymphoscintigraphy, and PET are used for evaluation. Understanding these methods and collaborating with clinicians are essential for treatment and survival.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Angele Bonnin, Carole Durot, Manel Djelouah, Anthony Dohan, Lionel Arrive, Pascal Rousset, Christine Hoeffel
Summary: The perihepatic space is commonly involved in various diseases, including intrahepatic lesions extending to the liver capsule and disease conditions from adjacent organs. The dissemination of peritoneal processes can also affect this space. MRI is valuable in assessing and diagnosing infectious, tumor-related, and other conditions in the perihepatic area compared to CT.
KOREAN JOURNAL OF RADIOLOGY
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Masaya Kawaguchi, Hiroki Kato, Yoshifumi Noda, Kazuhiro Kobayashi, Tatsuhiko Miyazaki, Fuminori Hyodo, Masayuki Matsuo
Summary: Accurate preoperative diagnosis is crucial for malignant skin tumors (MSTs) due to the different clinical management required for each histological subtype. Radiological imaging plays a significant role in evaluating the extent of local invasion, nodal involvement, and distant metastasis in MSTs. Recent studies have identified characteristic radiological features that aid in the differential diagnosis of MSTs, such as configuration, intratumoral homogeneity, signal intensity, cyst formation, and hemorrhage. Clinical data, including age, gender, and site of occurrence, are also important for determining the histological subtype of MSTs.
INSIGHTS INTO IMAGING
(2022)
Article
Cardiac & Cardiovascular Systems
Raymundo A. Quintana, Tiffany Dong, Ramya Vajapey, Reza Reyaldeen, Deborah H. Kwon, Serge Harb, Tom Kai Ming Wang, Allan L. Klein
Summary: Atrial fibrillation (AF) is the most common arrhythmia worldwide and is often managed using multimodality imaging techniques, including transesophageal echocardiography and computed tomography. Imaging plays a crucial role in excluding left atrial thrombus before cardioversion and during left atrial appendage occlusion device implantation.
CIRCULATION-CARDIOVASCULAR IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Andrea Ponsiglione, Arnaldo Stanzione, Gaia Spadarella, Agah Baran, Luca Alessandro Cappellini, Kevin Groot Lipman, Peter Van Ooijen, Renato Cuocolo
Summary: The overall methodological rigor of radiomics studies in the ovarian field is not ideal, with a lack of prospective design and formal validation of results. This limits the reproducibility of results and potential translation to clinical setting.
EUROPEAN RADIOLOGY
(2023)
Review
Multidisciplinary Sciences
Bita Abbasi, Reza Akhavan, Afshar Ghamari Khameneh, Gisoo Darban Hosseini Amirkhiz, Hossein Rezaei-Dalouei, Shamim Tayebi, Jahanbakhsh Hashemi, Behzad Aminizadeh, Sanam Darban Hosseini Amirkhiz
Summary: Hydatid disease is a worldwide zoonosis with a wide geographic distribution, commonly found in almost all parts of the body. Ultrasound, CT, and MRI are commonly used imaging modalities for diagnosis. MRI and CT are particularly useful when ultrasound is not accessible or surgical treatment is necessary.
Review
Radiology, Nuclear Medicine & Medical Imaging
Trinh Nguyen, Akshya Gupta, Shweta Bhatt
Summary: Lymphomatous involvement of the genitourinary system, particularly the kidneys, is often underestimated and underreported on conventional diagnostic imaging. This is due to its variable imaging appearance and overlapping features with other conditions. By presenting a spectrum of typical and atypical appearances of renal lymphoma using multimodality imaging, this article highlights the importance of imaging in the detection, diagnosis, staging, and surveillance of patients with lymphoma.
INSIGHTS INTO IMAGING
(2022)
Review
Oncology
Trinh Nguyen, Priya R. Bhosale, Lorena Cassia, Venkateswar Surabhi, Sanaz Javadi, Andrea Milbourne, Silvana C. Faria
Summary: With the increasing average age of pregnancy and the use of prenatal fetal noninvasive screening techniques, more cases of cancer are being diagnosed in pregnant women. This poses complex challenges in terms of imaging, diagnosis, staging, and treatment, requiring specialized interdisciplinary management. This report discusses the use of multimodality imaging and safety considerations, reviews current guidelines for ionizing radiation imaging techniques, and presents diagnostic imaging guidelines for common and uncommon cancers in pregnancy.
Review
Nutrition & Dietetics
Sophie Mavrogeni, Flora Bacopoulou, George Markousis-Mavrogenis, George Chrousos, Evangelia Charmandari
Summary: Obesity is a major public health challenge, contributing to approximately 5% of global deaths, primarily due to cardiovascular disease. Cardiovascular noninvasive imaging offers early and accurate information for obese individuals, but traditional techniques have limitations in this population.
Article
Radiology, Nuclear Medicine & Medical Imaging
Henriettae Stahlbrandt, Ida Bjornfot, Torsten Cederlund, Anja Almen
Summary: The numbers of CT and MRI examinations per capita are increasing in Sweden and other parts of Europe. This study audited the appropriateness of these examinations using European criteria and explored alternative modalities. The results were compared with a previous study in Sweden.
INSIGHTS INTO IMAGING
(2023)
Article
Rheumatology
Michail K. Alevizos, Sonye K. Danoff, Dimitrios A. Pappas, David J. Lederer, Cheilonda Johnson, Eric A. Hoffman, Elana J. Bernstein, Joan M. Bathon, Jon T. Giles
Summary: This study aimed to assess predictors for subclinical rheumatoid arthritis-associated interstitial lung disease (RA-ILD) using quantitative lung densitometry (qLD). The results showed that high baseline percentage of lung parenchyma with high attenuation areas (%HAA) was associated with factors such as female sex, higher pack-years of smoking, higher BMI, and anti-CCP >= 200 units. Predictors for %HAA increase included higher baseline %HAA, presence of MUC5B minor allele, and absence of HLA-DRB1 shared epitope.
Article
Radiology, Nuclear Medicine & Medical Imaging
Abhaya P. Trivedi, Chase Hall, Charles W. Goss, Daphne Lew, James G. Krings, Mary Clare McGregor, Maanasi Samant, Jered P. Sieren, Huashi Li, Ken B. Schechtman, Joshua Schirm, Stephen McEleney, Sam Peterson, Wendy C. Moore, Eugene R. Bleecker, Deborah A. Meyers, Elliot Israel, George R. Washko, Bruce D. Levy, Joseph K. Leader, Sally E. Wenzel, John Fahy, Mark L. Schiebler, Sean B. Fain, Nizar N. Jarjour, David T. Mauger, Joseph M. Reinhardt, John D. Newell, Eric A. Hoffman, Mario Castro, Ajay Sheshadri
Summary: Quantitative CT assessments of lung expansion distinguished well-established clinical phenotypes among participants with asthma, showing that lower whole-lung Jacobian and ADI values were associated with greater disease severity, and within-lung Jacobian and ADI values decreased as severity worsened.
Article
Respiratory System
John S. Kim, Jinhye Kim, Xiaorui Yin, Grant T. Hiura, Michaela R. Anderson, Eric A. Hoffman, Ganesh Raghu, Imre Noth, Ani Manichaikul, Stephen S. Rich, Benjamin M. Smith, Anna J. Podolanczuk, Christine Kim Garcia, R. Graham Barr, Martin R. Prince, Elizabeth C. Oelsner
Summary: The study found that hiatus hernia is associated with markers of lung inflammation and fibrosis, especially among MUC5B risk allele carriers. It also showed that hiatus hernia is associated with interstitial lung abnormalities in younger adults and an increase in serum matrix metalloproteinase-7 levels among smokers.
EUROPEAN RESPIRATORY JOURNAL
(2023)
Review
Respiratory System
Ishan Garg, Aditi Vidholia, Ankita Garg, Shuchita Singh, Alireza Agahi, Archana Laroia, Sachin S. Saboo, Alejandro P. Comellas, Eric A. Hoffman, Prashant Nagpal
Summary: Aggressive marketing and lack of regulations have led to the widespread adoption of electronic nicotine delivery systems (ENDS) or vaping devices as alternatives to cigarette smoking, especially among youth. However, this has resulted in a sudden increase in acute lung injuries, known as electronic cigarette or vaping product use-associated lung injury (EVALI). The use of vitamin E acetate as a diluent for marijuana oils has been linked to EVALI.
RESPIRATORY INVESTIGATION
(2022)
Article
Critical Care Medicine
Matthew C. Tattersall, Kristine E. Lee, Nanae Tsuchiya, Fauzia Osman, Claudia E. Korcarz, Kristin M. Hansen, Michael C. Peters, John Fahy, Colin A. Longhurst, Eleanor Dunican, Sally E. Wentzel, Joseph K. Leader, Elliot Israel, Bruce D. Levy, Mario Castro, Serpil C. Erzurum, Jason Lempel, Wendy C. Moore, Eugene R. Bleecker, Brenda R. Phillips, David T. Mauger, Eric A. Hoffman, Sean B. Fain, Scott B. Reeder, Ron L. Sorkness, Nizar N. Jarjour, Loren C. Denlinger, Mark L. Schiebler
Summary: Extrapulmonary manifestations of asthma, including fatty infiltration in tissues, may reflect systemic inflammation and influence lung function and disease severity. This study found that skeletal muscle adiposity is associated with lung function decline in women with asthma, but not in men.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Critical Care Medicine
Brigid A. Adviento, Elizabeth A. Regan, Barry J. Make, MeiLan K. Han, Marilyn G. Foreman, Anand S. Iyer, Surya P. Bhatt, Victor Kim, Jessica Bon, Xavier Soler, Gregory L. Kinney, Nicola A. Hanania, Katherine E. Lowe, Kristen E. Holm, Abebaw M. Yohannes, Gen Shinozaki, Karin F. Hoth, Jess G. Fiedorowicz
Summary: Studies have shown that there is an increased suicide risk associated with COPD and smoking. However, there have been no prospective studies examining suicide risk among individuals with smoking exposure along a spectrum of pulmonary diseases.
Letter
Respiratory System
Motahareh Vameghestahbanati, Coralynn Sack, Artur Wysoczanski, Eric A. Hoffman, Elsa Angelini, Norrina B. Allen, Alain G. Bertoni, Junfeng Guo, David R. Jacobs Jr, Joel D. Kaufman, Andrew Laine, Ching-Long Lin, Daniel Malinsky, Erin D. Michos, Elizabeth C. Oelsner, Steven J. Shea, Karol E. Watson, Andrea Benedetti, R. Graham Barr, Benjamin M. Smith
EUROPEAN RESPIRATORY JOURNAL
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Sean B. Fain, Mark L. Schiebler
Letter
Respiratory System
Andrew D. Hahn, Katie J. Carey, Gregory P. Barton, Luis A. Torres, Jeff Kammerman, Robert V. Cadman, Kristine E. Lee, Mark L. Schiebler, Nathan Sandbo, Sean B. Fain
Editorial Material
Critical Care Medicine
Sean B. Fain, Alejandro P. Comellas
Article
Respiratory System
James L. Mulshine, Carolyn R. Aldige, Laurie Fenton Ambrose, Samuel G. Armato, Ricardo S. Avila, Matt Cham, Raul San Jose Estepar, Sean B. Fain, Lee Gazourian, David S. Gierada, Charles Hatt, Claudia Henschke, Jody Hoyos, David A. Lynch, Anita K. McGlothlin, Matthijs Oudkerk, Mary Pasquinelli, Paul Pinsky, Bruce Pyenson, Albert A. Rizzo, Sheila M. Ross, Kathryn H. Schmitz, Mario Silva, Tochukwu Okwuosa, George Washko, Juan Wisnivesky, David F. Yankelevitz, Javier J. Zulueta
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2023)
Article
Respiratory System
John S. Kim, Ali Azarbarzin, Anna J. Podolanczuk, Michaela R. Anderson, Brian E. Cade, Steven M. Kawut, Artur Wysoczanski, Andrew F. Laine, Eric A. Hoffman, Daniel J. Gottlieb, Christine Kim Garcia, R. Graham Barr, Susan Redline
Summary: This study aimed to investigate the association between obstructive sleep apnea (OSA) and interstitial lung disease (ILD) as well as its impact on lung function. The results showed that OSA severity was associated with an increase in high-attenuation areas (HAAs) and a decline in lung volumes over time, indicating OSA may be a contributing factor in the early stages of ILD.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2023)
Article
Respiratory System
Connie C. W. Hsia, Jason H. T. Bates, Bastiaan Driehuys, Sean B. Fain, Jonathan G. Goldin, Eric A. Hoffman, James C. Hogg, David L. Levin, David A. Lynch, Matthias Ochs, Grace Parraga, G. Kim Prisk, Benjamin M. Smith, Merryn Tawhai, Marcos F. Vidal Melo, Jason C. Woods, Susan R. Hopkins
Summary: Multiple thoracic imaging modalities have been developed to link structure to function in the diagnosis and monitoring of lung disease. These modalities include volumetric computed tomography (CT), positron emission tomography (PET), and magnetic resonance imaging (MRI) using ultrashort-echo time (UTE) sequences. These imaging techniques provide valuable information on lung structures, dynamic physiological data, and airway function. The use of quantitative imaging (QI)-derived endpoints and computational modeling is emphasized for unbiased quantification, accurate metric derivation, and interpretation of in vivo imaging data.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2023)
Article
Respiratory System
Jamuna K. Krishnan, Kayley M. Ancy, Clara Oromendia, Katherine L. Hoffman, Imaani Easthausen, Nancy K. Leidy, MeiLan K. Han, Russell P. Bowler, Stephanie A. Christenson, David J. Couper, Gerard J. Criner, Jeffrey L. Curtis, Mark T. Dransfield, Nadia N. Hansel, Anand S. Iyer, Robert Paine, Stephen P. Peters, Jadwiga A. Wedzicha, Prescott G. Woodruff, Karla V. Ballman, Fernando J. Martinez
Summary: This study compares different statistical measures of symptom variability in patients with chronic obstructive pulmonary disease (COPD) and identifies characteristics of individuals with higher symptom variability. The within-subject standard deviation (WS-SD) method is found to be a useful measure of symptom variability and is associated with worse health-related quality of life in COPD patients.
CHRONIC OBSTRUCTIVE PULMONARY DISEASES-JOURNAL OF THE COPD FOUNDATION
(2022)
