Effect of Influenza A(H5N1) Vaccine Prepandemic Priming on CD4+ T-Cell Responses

Healthy Human Subjects Have CD4+ T Cells Directed against H5N1 Influenza Virus

(2014) M. Roti et al.   JOURNAL OF IMMUNOLOGY

A Live Attenuated Influenza A(H5N1) Vaccine Induces Long-Term Immunity in the Absence of a Primary Antibody Response

(2014) Kawsar R. Talaat et al.   JOURNAL OF INFECTIOUS DISEASES

Heterologous Prime-Boost Vaccination with MF59-Adjuvanted H5 Vaccines Promotes Antibody Affinity Maturation towards the Hemagglutinin HA1 Domain and Broad H5N1 Cross-Clade Neutralization

(2014) Surender Khurana et al.   PLoS One

T-cell subsets in the germinal center

(2013) Roybel R. Ramiscal et al.   IMMUNOLOGICAL REVIEWS

Cutting Edge: Heterosubtypic Influenza Infection Antagonizes Elicitation of Immunological Reactivity to Hemagglutinin

(2013) J. L. Nayak et al.   JOURNAL OF IMMUNOLOGY

CD4 T Cell Help Is Limiting and Selective during the Primary B Cell Response to Influenza Virus Infection

(2013) S. Alam et al.   JOURNAL OF VIROLOGY

Human circulating influenza-CD4+ ICOS1+IL-21+ T cells expand after vaccination, exert helper function, and predict antibody responses

(2013) F. Spensieri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of ICOS+CXCR3+CXCR5+ TH Cells Correlates with Antibody Responses to Influenza Vaccination

(2013) S.-E. Bentebibel et al.   Science Translational Medicine

Germinal center selection and the development of memory B and plasma cells

(2012) Mark J. Shlomchik et al.   IMMUNOLOGICAL REVIEWS

The origins, function, and regulation of T follicular helper cells

(2012) Cindy S. Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD4+ T-Cell Expansion Predicts Neutralizing Antibody Responses to Monovalent, Inactivated 2009 Pandemic Influenza A(H1N1) Virus Subtype H1N1 Vaccine

(2012) Jennifer L. Nayak et al.   JOURNAL OF INFECTIOUS DISEASES

T-Helper 1 Cells Elicited by H5N1 Vaccination Predict Seroprotection

(2012) Gabriel K. Pedersen et al.   JOURNAL OF INFECTIOUS DISEASES

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

(2012) Tom M Wilkinson et al.   NATURE MEDICINE

A Randomized Clinical Trial of an Inactivated Avian Influenza A (H7N7) Vaccine

(2012) Robert B. Couch et al.   PLoS One

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

The Potential for Respiratory Droplet-Transmissible A/H5N1 Influenza Virus to Evolve in a Mammalian Host

(2012) C. A. Russell et al.   SCIENCE

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Safety and Immunogenicity of Influenza A H5 Subunit Vaccines: Effect of Vaccine Schedule and Antigenic Variant

(2011) Robert B. Belshe et al.   JOURNAL OF INFECTIOUS DISEASES

Infection with Seasonal Influenza Virus Elicits CD4 T Cells Specific for Genetically Conserved Epitopes That Can Be Rapidly Mobilized for Protective Immunity to Pandemic H1N1 Influenza Virus

(2011) S. Alam et al.   JOURNAL OF VIROLOGY

Germinal center B and follicular helper T cells: siblings, cousins or just good friends?

(2011) Stephen L Nutt et al.   NATURE IMMUNOLOGY

Safety and immunogenicity of an MF59®-adjuvanted A/H5N1 pre-pandemic influenza vaccine in adults and the elderly

(2011) Timo Vesikari et al.   VACCINE

Cutting Edge: CD4 T Cells Generated from Encounter with Seasonal Influenza Viruses and Vaccines Have Broad Protein Specificity and Can Directly Recognize Naturally Generated Epitopes Derived from the Live Pandemic H1N1 Virus

(2010) K. A. Richards et al.   JOURNAL OF IMMUNOLOGY

Vaccinate before the next pandemic?

(2010) Klaus Stöhr   NATURE

Immunogenicity and Safety of MF59-Adjuvanted H5N1 Influenza Vaccine From Infancy to Adolescence

(2010) T. Vesikari et al.   PEDIATRICS

In Vitro Responses to Avian Influenza H5 by Human CD4 T Cells

(2009) M. F. Cusick et al.   JOURNAL OF IMMUNOLOGY

Infection of HLA-DR1 Transgenic Mice with a Human Isolate of Influenza A Virus (H1N1) Primes a Diverse CD4 T-Cell Repertoire That Includes CD4 T Cells with Heterosubtypic Cross-Reactivity to Avian (H5N1) Influenza Virus

(2009) K. A. Richards et al.   JOURNAL OF VIROLOGY

Immunogenicity and adverse events of avian influenza A H5N1 vaccine in healthy adults: multiple-treatments meta-analysis

(2009) Lamberto Manzoli et al.   LANCET INFECTIOUS DISEASES

Fast rise of broadly cross-reactive antibodies after boosting long-lived human memory B cells primed by an MF59 adjuvanted prepandemic vaccine

(2009) G. Galli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adjuvanted H5N1 vaccine induces early CD4+ T cell response that predicts long-term persistence of protective antibody levels

(2009) G. Galli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A phase I clinical trial of a PER.C6® cell grown influenza H7 virus vaccine

(2009) Rebecca J. Cox et al.   VACCINE

B cell responses to H5 influenza HA in human subjects vaccinated with a drifted variant

(2009) Jane Baer et al.   VACCINE

Selective CD4+ T Cell Help for Antibody Responses to a Large Viral Pathogen: Deterministic Linkage of Specificities

(2008) Alessandro Sette et al.   IMMUNITY

Effects of Adjuvants on the Safety and Immunogenicity of an Avian Influenza H5N1 Vaccine in Adults

(2008) David I. Bernstein et al.   JOURNAL OF INFECTIOUS DISEASES

Immune Responses of Healthy Subjects to a Single Dose of Intramuscular Inactivated Influenza A/Vietnam/1203/2004 (H5N1) Vaccine after Priming with an Antigenic Variant

(2008) Nega Ali Goji et al.   JOURNAL OF INFECTIOUS DISEASES

Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China

(2008) Hua Wang et al.   LANCET

Antigenically Distinct MF59-Adjuvanted Vaccine to Boost Immunity to H5N1

(2008) Iain Stephenson et al.   NEW ENGLAND JOURNAL OF MEDICINE