Genetic engineering combined with random mutagenesis to enhance G418 production in Micromonospora echinospora

DNA assembly techniques for next-generation combinatorial biosynthesis of natural products

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Actinomycetes biosynthetic potential: how to bridge in silico and in vivo?

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Construction of a gentamicin C1a-overproducing strain of Micromonospora purpurea by inactivation of the gacD gene

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The Last Step of Kanamycin Biosynthesis: Unique Deamination Reaction Catalyzed by the α-Ketoglutarate-Dependent Nonheme Iron Dioxygenase KanJ and the NADPH-Dependent Reductase KanK

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The oxidoreductases LivQ and NeoQ are responsible for the different 6′-modifications in the aminoglycosides lividomycin and neomycin

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MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation

(2011) Je Won Park et al.   Nature Chemical Biology

Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus

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Biosynthesis of 3′-Deoxy-carbamoylkanamycin C in a Streptomyces tenebrarius Mutant Strain by tacB Gene Disruption

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Gene inactivation study of gntE reveals its role in the first step of pseudotrisaccharide modifications in gentamicin biosynthesis

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Genetic dissection of the biosynthetic route to gentamicin A2 by heterologous expression of its minimal gene set

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