Robust preparative-scale extracellular production of hirudin in Escherichia coli and its purification and characterization

Extracellular secretion of anticoagulant peptide hirudin in Lactococcus lactis using SP310mut2 signal peptide

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Extracellular recombinant protein production from Escherichia coli

(2009) Ye Ni et al.   BIOTECHNOLOGY LETTERS

High cell density cultivation of recombinant E. coli for hirudin variant 1 production by temperature shift controlled by pUC18-based replicative origin

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Expression of recombinant Hirudin in transgenic mice milk driven by the goat β-casein promoter

(2008) Chon-Ho Yen et al.   Biotechnology Journal

Potential use of hirudin in diabetic cataract: A study of galactose mediated human lens epithelial cells injury

(2008) Yu Ou et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Intracellular GSH and ROS levels may be related to galactose-mediated human lens epithelial cell apoptosis: Role of recombinant hirudin variant III

(2008) Yu Ou et al.   CHEMICO-BIOLOGICAL INTERACTIONS

High cell density cultivation of recombinant Escherichia coli for hirudin variant 1 production

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