Recent Developments in the Synthesis of Unsymmetrical Disulfanes (Disulfides). A Review

Recent advances in S–S bond formation

(2014) Bablee Mandal et al.   RSC Advances

Synthesis and activity of a folate targeted monodisperse PEG camptothecin conjugate

(2013) Walter A. Henne et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological evaluation of nonsymmetrical aromatic disulfides as novel inhibitors of acetohydroxyacid synthase

(2013) Zai-Shun Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Mutual prodrugs containing bio-cleavable and drug releasable disulfide linkers

(2013) Arun K. Jain et al.   BIOORGANIC CHEMISTRY

Disulfide-Cleavage-Triggered Chemosensors and Their Biological Applications

(2013) Min Hee Lee et al.   CHEMICAL REVIEWS

TBAF Promoted Formation of Symmetrical Trisulfides

(2013) Slawomir Lach et al.   HETEROATOM CHEMISTRY

Efficient Synthesis of Functionalized Unsymmetrical Dialkyl Trisulfanes

(2013) Dariusz Witt et al.   SYNLETT

Total synthesis of α-conotoxin MII using a soluble-tag-assisted method

(2013) Shingo Kitada et al.   TETRAHEDRON

A convergent synthesis of homogeneous reducible polypeptides

(2013) Mark D. Ericson et al.   TETRAHEDRON LETTERS

An efficient and convenient synthesis of unsymmetrical disulfides from thioacetates

(2013) Slawomir Lach et al.   TETRAHEDRON LETTERS

Synthesis of glycosyl disulfides containing an α-glycosidic linkage

(2013) Raymond Smith et al.   TETRAHEDRON LETTERS

Structure–activity studies on the anti-proliferation activity of ajoene analogues in WHCO1 oesophageal cancer cells

(2012) Catherine H. Kaschula et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Crystal Structure, in Vitro Acetohydroxyacid Synthase Inhibition, in Vivo Herbicidal Activity, and 3D-QSAR of New Asymmetric Aryl Disulfides

(2012) Jun Shang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Direct Fluorescence Monitoring of the Delivery and Cellular Uptake of a Cancer-Targeted RGD Peptide-Appended Naphthalimide Theragnostic Prodrug

(2012) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Capture and Visualization of Hydrogen Sulfide by a Fluorescent Probe

(2011) Chunrong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydrophobic tag-assisted liquid-phase synthesis of a growth hormone-inhibiting peptide somatostatin

(2011) Shingo Kitada et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and activity of folate conjugated didemnin B for potential treatment of inflammatory diseases

(2011) Walter A. Henne et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Glycosylation via mixed disulfide formation using glycosylthio-phthalimides and -succinimides as glycosylsulfenyl-transfer reagents

(2011) Tünde-Zita Illyés et al.   CARBOHYDRATE RESEARCH

Design, synthesis and biological evaluation of brain-specific glucosyl thiamine disulfide prodrugs of naproxen

(2011) Wei Fan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Trityl Radical-Conjugated Disulfide Biradicals for Measurement of Thiol Concentration

(2011) Yangping Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

A Ratiometric Fluorescent Probe for Thiols Based on a Tetrakis(4-hydroxyphenyl)porphyrin–Coumarin Scaffold

(2011) Xiaowei Cao et al.   JOURNAL OF ORGANIC CHEMISTRY

Responsive Small Molecular Hydrogels Based on Adamantane–Peptides for Cell Culture

(2011) Cuihong Yang et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Cell-Specific, Activatable, and Theranostic Prodrug for Dual-Targeted Cancer Imaging and Therapy

(2011) Santimukul Santra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hepatocyte-Targeting Single Galactose-Appended Naphthalimide: A Tool for Intracellular Thiol Imaging in Vivo

(2011) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient synthesis of unsymmetrical disulfides

(2011) Jaya Kishore Vandavasi et al.   TETRAHEDRON

Synthesis of novel amphiphilic conjugates with a biological recognition function for developing targeted triggered liposomal delivery systems

(2011) Nicolai Brodersen et al.   TETRAHEDRON

Total syntheses of chaetocin and ent-chaetocin

(2011) Eriko Iwasa et al.   TETRAHEDRON

Synthesis of novel steroid analogues containing nitrile and disulfide moieties via palladium-catalyzed cross-coupling reactions

(2011) Christoph D. Mayer et al.   TETRAHEDRON

Reversible α-helix formation controlled by a hydrogen bond surrogate

(2011) Stephen E. Miller et al.   TETRAHEDRON

Mechanism-Based Tumor-Targeting Drug Delivery System. Validation of Efficient Vitamin Receptor-Mediated Endocytosis and Drug Release

(2010) Shuyi Chen et al.   BIOCONJUGATE CHEMISTRY

Disulfide bond as a cleavable linker for molecular self-assembly and hydrogelation

(2010) Chunhua Ren et al.   CHEMICAL COMMUNICATIONS

Synthesis and Biological Analysis of Prostate-Specific Membrane Antigen-Targeted Anticancer Prodrugs

(2010) Sumith A. Kularatne et al.   JOURNAL OF MEDICINAL CHEMISTRY

Efficient Microwave-Assisted Synthesis of Unsymmetrical Disulfides

(2010) Kristina Görmer et al.   JOURNAL OF ORGANIC CHEMISTRY

A Two-Photon Fluorescent Probe for Thiols in Live Cells and Tissues

(2010) Jun Han Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Redox-Sensitive Disassembly of Amphiphilic Copolymer Based Micelles

(2010) Ja-Hyoung Ryu et al.   LANGMUIR

One-pot synthesis of unsymmetrical disulfides using 1-chlorobenzotriazole as oxidant: Interception of the sulfenyl chloride intermediate

(2010) Nashia Stellenboom et al.   TETRAHEDRON

A high-yielding, one-pot preparation of unsymmetrical glycosyl disulfides using 1-chlorobenzotriazole as an in situ trapping/oxidizing agent

(2010) Nashia Stellenboom et al.   TETRAHEDRON LETTERS

A traceless, one-pot preparation of unsymmetric disulfides from symmetric disulfides through a repeated process involving sulfenic acid and thiosulfinate intermediates

(2010) Minsoo Han et al.   TETRAHEDRON LETTERS

Histone deacetylase and microtubules as targets for the synthesis of releasable conjugate compounds

(2009) Daniele Passarella et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Interactions of aromatic mannosyl disulfide derivatives with Concanavalin A: synthesis, thermodynamic and NMR spectroscopy studies

(2009) Bandaru Narasimha Murthy et al.   CARBOHYDRATE RESEARCH

Identification of an acetyl disulfide derivative in the synthesis of thiosialosides

(2009) Goreti Ribeiro Morais et al.   CARBOHYDRATE RESEARCH

Histone deacetylase inhibitor prodrugs in nanoparticle vector enhanced gene expression in human cancer cells

(2009) Yuta Ishii et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Direct Synthesis of Functionalized Unsymmetrical β-Sulfonamido Disulfides by Tetrathiomolybdate Mediated Aziridine Ring-Opening Reactions

(2009) Devarajulu Sureshkumar et al.   JOURNAL OF ORGANIC CHEMISTRY

RAFT controlled synthesis of six-armed biodegradable star polymeric architectures via a ‘core-first’ methodology

(2009) Jingquan Liu et al.   POLYMER

Unsymmetric aryl–alkyl disulfide growth inhibitors of methicillin-resistant Staphylococcus aureus and Bacillus anthracis

(2008) Edward Turos et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives

(2008) Malcolm W.B. McCulloch et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Substituted ajoenes as novel anti-cancer agents

(2008) Roger Hunter et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, Synthesis and Biological Evaluation of Glutathione Peptidomimetics as Components of Anti-Parkinson Prodrugs

(2008) Swati S. More et al.   JOURNAL OF MEDICINAL CHEMISTRY

Selective Disruption of Early/Recycling Endosomes: Release of Disulfide-Linked Cargo Mediated by aN-Alkyl-3β-Cholesterylamine-Capped Peptide

(2008) Qi Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorescence Imaging of Cellular Glutathione Using a Latent Rhodamine

(2008) Marcos M. Pires et al.   ORGANIC LETTERS