Article
Nanoscience & Nanotechnology
Muhammad Shuaib Khan, Minoru Osada, Lei Dong, Yoon-Hyun Kim, Yasuo Ebina, Takayoshi Sasaki
Summary: This study presents a controlled assembly strategy for fabricating atomically precise interfaces of two-dimensional homologous perovskite nanosheets to construct artificial superlattices. By engineering the interfacial properties, materials with superior high-k properties and ferroelectricity can be tailored for specific design purposes.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Organic
Akito Shibuya, Moeko Kato, Asuka Saito, Sujit Manmode, Naoto Nishikori, Toshiyuki Itoh, Aiichiro Nagaki, Toshiki Nokami
Summary: This study found that the stability of glycosyl dioxalenium ions can be enhanced by introducing tert-butyldiphenylsilyl group at 6-OH, allowing reactions to be performed at elevated temperatures. NMR and VT-NMR measurements revealed the impact of protecting groups on the stability of intermediates, leading to the successful synthesis of a trisaccharide with a glucoside β-1,6 linkage.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Medicine, Research & Experimental
Danyang Gong, Timothy P. Riley, Krzysztof P. Bzymek, Ana R. Correia, Danqing Li, Christopher Spahr, John H. Robinson, Ryan B. Case, Zhulun Wang, Fernando Garces
Summary: Bispecific antibodies have the potential for therapeutic intervention in complex diseases, but their correct assembly of multiple polypeptide chains is crucial for industrial-scale production. Chain Selectivity Assessment (CSA) can help in rationally selecting parental monoclonal antibodies to produce bispecific antibodies with optimal manufacturability properties, including a native preference for chain pairing and rare light chain identification for positive binding.
Article
Mathematical & Computational Biology
Yuewu Liu, Mengfang Zeng, Shengyong Liu, Chun Li
Summary: Virus assembly is a crucial step in virus replication and offers potential drug targets. This process involves the polymerization of virus structural protein monomers into building blocks, which then assemble into virus shells. In this study, we developed five dynamical models to describe the synthesis reactions for different types of building blocks. We proved the existence and uniqueness of positive equilibrium solutions for each model and analyzed the stability of these equilibrium states. Our results suggest that the concentration of dimer building blocks decreases as the ratio of off-rate constant to on-rate constant increases. Similarly, trimer building blocks decrease with an increasing ratio of off-rate constant to on-rate constant. These findings provide insights into the dynamic properties of virus-building block synthesis in vitro.
MATHEMATICAL BIOSCIENCES AND ENGINEERING
(2023)
Article
Chemistry, Inorganic & Nuclear
Xiaodan Jia, Jun Jiang, Lulu Liu, Lina Meng, Lijuan Chen, Junwei Zhao
Summary: Two particular lanthanide-encapsulated selenotungstates were synthesized using a step-by-step synthetic strategy, and a beehive-shaped electrochemical biosensor was prepared for detecting a mycotoxin. This study demonstrates the feasibility of using long-chain flexible ligands to build complex structures and the potential application of polyoxometalate-involved materials in bioanalysis.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Physical
Zhijie Liu, Qiang Zhao, Shuitao Gao, Yun Yan, Baocai Xu, Cheng Ma, Jianbin Huang
Summary: A polymeric-like building block, nC12C6C12(Me)@n & gamma;-CD, was constructed and showed the ability to self-assemble into various nanostructures that can be reversibly transformed by multiple stimuli.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Chemistry, Organic
Dharmendra Singh, Durga Lakshmi, Chhuttan L. Meena, Gamidi Rama Krishna, Gangadhar J. Sanjayan
Summary: This paper reports on the development of carbamate-protected 2-aminopyrimidinedione-based Janus G-C nucleobases as building blocks for smart polymers and self-healing materials. These nucleobases feature polymerizable groups and self-complementary triple H-bonding motifs, enabling the synthesis of smart polymers and eliminating solubility issues.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Engineering, Manufacturing
Yan Gui, Zhifang Fei, Shuang Zhao, Zhen Zhang, Huilong Shao, Jun Chen, Kunfeng Li, Hu Du, Zichun Yang
Summary: A novel freeze casting-assisted extrusion printing method is proposed for the fabrication of honeycomb polyimide (PI) aerogels, with properties of the aerogels synchronously regulated by manipulating the ink viscosity and honeycomb porosity. A building block-assembly strategy is developed to fabricate two types of PI aerogel metamaterials for acoustic absorption, exhibiting enhanced overall sound absorption performance.
ADDITIVE MANUFACTURING
(2023)
Article
Chemistry, Inorganic & Nuclear
Zhigang Tang, Menglu Wang, Xiaodan Jia, Saisai Xie, Pei Chen, Dan Wang, Lijuan Chen, Junwei Zhao
Summary: Template-directed assembly of giant cluster-based nanomaterials is an everlasting theme in cluster science. In this work, a polyoxotungstate aggregate was prepared using an organic template and an inorganic template. The resulting composite showed excellent electrochemical sensing properties, especially for the detection of aflatoxin B1.
INORGANIC CHEMISTRY
(2022)
Article
Polymer Science
Hubert Buksa, Thomas J. Neal, Spyridon Varlas, Saul J. Hunter, Osama M. Musa, Steven P. Armes
Summary: The reversible addition-fragmentation chain transfer (RAFT) aqueous dispersion polymerization of 4-hydroxybutyl acrylate (HBA) with a carboxylic acid-based water-soluble RAFT agent at pH 8 leads to the formation of anionic PHBA latex particles of around 200 nm diameter. The weakly hydrophobic PHBA chains enable stimulus-responsive behavior in the latexes. Addition of water-miscible hydrophilic monomer, 2-(N-(acryloyloxy)-ethylpyrrolidone) (NAEP), allows for in situ molecular dissolution of the PHBA latex and subsequent formation of sterically stabilized PHBA-PNAEP diblock copolymer nanoparticles of around 57 nm diameter. This new approach to reverse sequence polymerization-induced self-assembly provides valuable insights.
Article
Chemistry, Organic
Kumpei Yano, Norihiko Sasaki, Toshiyuki Itoh, Toshiki Nokami
Summary: The research utilizes automated electrochemical assembly to synthesize oligosaccharides, successfully producing oligosaccharides with different chain lengths and developing a method to convert linear oligosaccharides into cyclic ones through electrochemical glycosylation.
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN
(2021)
Article
Chemistry, Physical
Jonathan Cisterna, Mauricio Fuentealba, Carolina Manzur, David Carrillo
Summary: This paper presents a new type of asymmetrical Fe(III) complex, which contains two different ligands in the equatorial and axial positions, showing potential as a building block for dipolar D-pi-A systems in the field of optoelectronic devices. The compound features a distorted square base pyramid geometry and centrosymmetric crystal packing, providing insights for the construction of novel compounds in the field of optoelectronic devices.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Geosciences, Multidisciplinary
Zhenning Yang, Zhiwei Wang, Liyang Zhang, Bei Xu, Linjie Yan
Summary: The Xing'an-Airgin Sum Block in central and northern Inner Mongolia, China, contains Mesoproterozoic to early Neoproterozoic stratigraphic sequences formed in coastal marine and shallow marine sedimentary environments, influenced by clastic and carbonate provenances. The sedimentary analysis reveals the presence of two different types of sedimentary basins formed at different times, as well as the generation of syenogranites and alkali-feldspar granites in an extensional setting. The tectonic evolution of the XAB is characterized by three sedimentary stages and two magmatic events, reflecting the response to the supercontinent cycle from the Nuna breakup to the Rodinia assembly.
PRECAMBRIAN RESEARCH
(2021)
Proceedings Paper
Automation & Control Systems
Hao Zhang, Jun Zhou, Guanghui Liu
Summary: This paper proposes a modular microsatellite scheme based on building block assembly for rapid, low-cost and batch development of microsatellites. Cube modules are used as the basic units, allowing for the assembly of microsatellites with specific functions. The proposed scheme includes a modular microsatellite system architecture with plug-and-play hardware, reconfigurable onboard software, and a rapid integration and testing system. The advantages of the scheme are demonstrated through a 6U microsatellite case study.
PROCEEDINGS OF 2022 INTERNATIONAL CONFERENCE ON AUTONOMOUS UNMANNED SYSTEMS, ICAUS 2022
(2023)
Article
Chemistry, Multidisciplinary
Heejin Kim, Yuya Yonekura, Jun-ichi Yoshida
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2018)
Article
Chemistry, Multidisciplinary
Ryutaro Hayashi, Akihiro Shimizu, Jonathan A. Davies, Yu Ishizaki, Chris Willis, Jun-ichi Yoshida
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2018)
Article
Electrochemistry
Akihiro Shimizu
Article
Chemistry, Organic
Yu Miyamoto, Naoya Mitani, Rina Yanagi, Shigenori Kashimura, Seiji Suga, Jun-ichi Yoshida, Kouichi Matsumoto
Article
Chemistry, Multidisciplinary
Shinobu Arikawa, Akihiro Shimizu, Ryo Shintani
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2019)
Article
Chemistry, Physical
Aiichiro Nagaki, Katsuyuki Hirose, Yuya Moriwaki, Masahiro Takumi, Yusuke Takahashi, Koji Mitamura, Kimihiro Matsukawa, Norio Ishizuka, Jun-ichi Yoshida
Article
Chemistry, Multidisciplinary
Sujit Manmode, Shichidai Tanabe, Takashi Yamamoto, Norihiko Sasaki, Toshiki Nokami, Toshiyuki Itoh
Article
Chemistry, Multidisciplinary
Lars J. Wesenberg, Erika Diehl, Till J. B. Zaehringer, Carolin Doerr, Dieter Schollmeyer, Akihiro Shimizu, Jun-Ichi Yoshida, Ute A. Hellmich, Siegfried R. Waldvogel
CHEMISTRY-A EUROPEAN JOURNAL
(2020)
Article
Chemistry, Organic
Akihiro Shimizu, Yu Ishizaki, Shun Horiuchi, Takashi Hirose, Kenji Matsuda, Hiroyasu Sato, Jun-ichi Yoshida
Summary: The study focused on designing and synthesizing small pi-conjugated zwitterions with electron-donating anions and electron-accepting cations. By adjusting the energy difference and interplanar angle between the anion's HOMO and the cation's LUMO, the molecules exhibited small HOMO-LUMO energy gaps, showing amphoteric redox properties and near-infrared electronic absorption exceeding 1000 nm.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Ayane Kayama, Akihiro Shimizu, Ryo Shintani
Summary: The study describes the design and synthesis of a novel anthracene-based zwitterion with amphoteric redox properties and low-energy-light absorption. DFT calculations indicate that replacing C-H with N+-Me and introducing O- is essential for significantly altering the electronic structure and properties of anthracene.
SYNTHESIS-STUTTGART
(2021)
Article
Chemistry, Multidisciplinary
Shinobu Arikawa, Akihiro Shimizu, Daisuke Shiomi, Kazunobu Sato, Ryo Shintani
Summary: By introducing bulky substituents onto the reactive zigzag edges, a kinetically stabilized crystalline form of triangulene was successfully synthesized and isolated for the first time, opening up new possibilities for the synthesis and isolation of other hydrocarbons with higher spin multiplicity.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Akihiro Shimizu, Tetsuya Morikoshi, Kenji Sugisaki, Daisuke Shiomi, Kazunobu Sato, Takeji Takui, Ryo Shintani
Summary: This study describes the design, synthesis, and isolation of a Kekule hydrocarbon with a triplet ground state. The triplet ground state was confirmed through ESR experiments, and the structure and fundamental physical properties were also revealed. The key aspect of the molecular design is the decrease in bonding interaction in the singlet state through aromatic stabilization of benzene rings and the increase of exchange interaction of unpaired electrons, which is favorable for the triplet state. These findings contribute to the development of hydrocarbon-based organic magnetic materials.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Shinobu Arikawa, Akihiro Shimizu, Daisuke Shiomi, Kazunobu Sato, Takeji Takui, Hikaru Sotome, Hiroshi Miyasaka, Masahito Murai, Shigehiro Yamaguchi, Ryo Shintani
Summary: A kinetically-stabilized nitrogen-doped triangulene cation derivative with a triplet ground state that exhibits near-infrared emission has been synthesized and isolated. The triplet ground state with a large singlet-triplet energy gap was experimentally confirmed by magnetic measurements. The nitrogen-doped triangulene cation derivative is highly stable even in solution under air and exhibits near-infrared absorption and emission due to the broken alternancy symmetry of triangulene.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Organic
Akihiro Shimizu, Shun Horiuchi, Ryutaro Hayashi, Kouichi Matsumoto, Yu Miyamoto, Yusuke Morisawa, Tomonari Wakabayashi, Jun-ichi Yoshida
Review
Chemistry, Multidisciplinary
Jun-ichi Yoshida, Akihiro Shimizu, Ryutaro Hayashi
