Systematic Synthesis of Inhibitors of the Two First Enzymes of the Bacterial Heptose Biosynthetic Pathway: Towards Antivirulence Molecules Targeting Lipopolysaccharide Biosynthesis

Structural Determinants of Substrate Recognition in the HAD Superfamily Memberd-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB),

(2010) Henry H. Nguyen et al.   BIOCHEMISTRY

Towards the synthesis of a Yersinia pestis cell wall polysaccharide: enantioselective synthesis of an l-glycero-d-manno-heptose building block

(2010) Takafumi Ohara et al.   CHEMICAL COMMUNICATIONS

The functional valency of dodecamannosylated fullerenes with Escherichia coli FimH—towards novel bacterial antiadhesives

(2010) Maxime Durka et al.   CHEMICAL COMMUNICATIONS

The Structure of Sedoheptulose-7-Phosphate Isomerase from Burkholderia pseudomallei Reveals a Zinc Binding Site at the Heart of the Active Site

(2010) Nicholas J. Harmer   JOURNAL OF MOLECULAR BIOLOGY

The crystal structure of the Y140F mutant of ADP-L-glycero-D-manno-heptose 6-epimerase bound to ADP-β-D-mannose suggests a one base mechanism

(2010) Thomas Kowatz et al.   PROTEIN SCIENCE

Towards Gram-negative antivirulence drugs: New inhibitors of HldE kinase

(2008) Nicolas Desroy et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of new Gram-negative antivirulence drugs: Structure and properties of novel E. coli WaaC inhibitors

(2008) F. Moreau et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Stereoselective Glycal Fluorophosphorylation: Synthesis of ADP-2-fluoroheptose, an Inhibitor of the LPS Biosynthesis

(2008) Hirofumi Dohi et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Synthesis of Azadirachtin: A Potent Insect Antifeedant

(2008) Steven V. Ley et al.   CHEMISTRY-A EUROPEAN JOURNAL

Antivirulence as a new antibacterial approach for chemotherapy

(2008) Sonia Escaich   CURRENT OPINION IN CHEMICAL BIOLOGY

Occurrence, Synthesis and Biosynthesis of Bacterial Heptoses

(2008) Paul Kosma   CURRENT ORGANIC CHEMISTRY

The biology and future prospects of antivirulence therapies

(2007) Lynette Cegelski et al.   NATURE REVIEWS MICROBIOLOGY