Germacrone induces apoptosis in human hepatoma HepG2 cells through inhibition of the JAK2/STAT3 signalling pathway

The liver X receptor promotes macrophage differentiation and suppresses osteoclast formation in mouse RAW264.7 promyelocytic leukemia cells exposed to bacterial lipopolysaccharide

(2012) Kirsten M. Robertson Remen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells

(2012) Jie Yang et al.   CANCER LETTERS

Targeting Stat3 Abrogates EGFR Inhibitor Resistance in Cancer

(2012) M. Sen et al.   CLINICAL CANCER RESEARCH

Anti-tumor effect of germacrone on human hepatoma cell lines through inducing G2/M cell cycle arrest and promoting apoptosis

(2012) Yunyi Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Management of HCC

(2012) Carlos Rodríguez de Lope et al.   JOURNAL OF HEPATOLOGY

Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction

(2012) Ching-Yu Yen et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Cosmomycin C inhibits signal transducer and activator of transcription 3 (STAT3) pathways in MDA-MB-468 breast cancer cell

(2011) Jihoon Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN

(2011) Ji Young Heo et al.   CANCER LETTERS

Germacrone inhibits the proliferation of breast cancer cell lines by inducing cell cycle arrest and promoting apoptosis

(2011) Zhangfeng Zhong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Activation of a pro-survival pathway IL-6/JAK2/STAT3 contributes to glial fibrillary acidic protein induction during the cholera toxin-induced differentiation of C6 malignant glioma cells

(2011) Minfeng Shu et al.   Molecular Oncology

HURP Expression-Assisted Risk Scores Identify Prognosis Distinguishable Subgroups in Early Stage Liver Cancer

(2011) Ming-Ling Chang et al.   PLoS One

Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells

(2010) Feng Li et al.   CANCER LETTERS

Efficient synthesis of the anticancer β-elemene and other bioactive elemanes from sustainable germacrone

(2010) Alejandro F. Barrero et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

STAT3 deletion sensitizes cells to oxidative stress

(2009) Seán P. Barry et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

(2009) Michael Hedvat et al.   CANCER CELL

Risk of HCC: Genetic heterogeneity and complex genetics

(2009) Tommaso A. Dragani   JOURNAL OF HEPATOLOGY