Rapid and scalable synthesis of innovative unnatural α,β or γ-amino acids functionalized with tertiary amines on their side-chains

Development of a Peptidomimetic Antagonist of Neuropeptide FF Receptors for the Prevention of Opioid-Induced Hyperalgesia

(2015) Frédéric Bihel et al.   ACS Chemical Neuroscience

Peptidomimetics via modifications of amino acids and peptide bonds

(2014) Ilker Avan et al.   CHEMICAL SOCIETY REVIEWS

Ligand-Controlled C(sp3)-H Arylation and Olefination in Synthesis of Unnatural Chiral  -Amino Acids

(2014) J. He et al.   SCIENCE

A Practical Procedure for Reduction of Primary, Secondary and Tertiary Amides to Amines

(2013) Jonathan T. Reeves et al.   ADVANCED SYNTHESIS & CATALYSIS

A Convenient and General Reduction of Amides to Amines with Low-Valent Titanium

(2013) Tongxin Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Cobalt Carbonyl-Based Catalyst for Hydrosilylation of Carboxamides

(2013) Thomas Dombray et al.   ADVANCED SYNTHESIS & CATALYSIS

Is JmjC Oxygenase Catalysis Limited to Demethylation?

(2013) Richard J. Hopkinson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Selective Reduction of Amides to Amines by Boronic Acid Catalyzed Hydrosilylation

(2013) Yuehui Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Facile and efficient KOH-catalysed reduction of esters and tertiary amides

(2013) José A. Fernández-Salas et al.   CHEMICAL COMMUNICATIONS

Homogeneous Catalytic Hydrogenation of Amides to Amines

(2013) Jacorien Coetzee et al.   CHEMISTRY-A EUROPEAN JOURNAL

Endogenous mammalian RF-amide peptides, including PrRP, kisspeptin and 26RFa, modulate nociception and morphine analgesia via NPFF receptors

(2013) Khadija Elhabazi et al.   NEUROPHARMACOLOGY

Cesium Carbonate-Catalyzed Reduction of Amides with Hydrosilanes

(2013) Weilong Xie et al.   ORGANOMETALLICS

Catalytic Hydrogenation of Amides to Amines under Mild Conditions

(2012) Mario Stein et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Future of Peptide-based Drugs

(2012) David J. Craik et al.   Chemical Biology & Drug Design

A general and selective copper-catalyzed reduction of secondary amides

(2012) Shoubhik Das et al.   CHEMICAL COMMUNICATIONS

Recent Advances in the Synthesis of Unnatural α-Amino Acids - An Updated Version

(2012) A. Perdih et al.   CURRENT ORGANIC CHEMISTRY

Iridium-Catalyzed Reduction of Secondary Amides to Secondary Amines and Imines by Diethylsilane

(2012) Chen Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-Specific Modification of Amino Acids and Peptides by Aldehyde–Alkyne–Amine Coupling under Ambient Aqueous Conditions

(2012) Nick Uhlig et al.   ORGANIC LETTERS

Zinc-Catalyzed Chemoselective Reduction of Tertiary and Secondary Amides to Amines

(2011) Shoubhik Das et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Efficient Gold Nanoparticle Catalyzed Deoxygenation of Amides, Sulfoxides, and Pyridine N-Oxides

(2011) Yusuke Mikami et al.   CHEMISTRY-A EUROPEAN JOURNAL

Development and Mechanistic Investigation of a Highly Efficient Iridium(V) Silyl Complex for the Reduction of Tertiary Amides to Amines

(2011) Sehoon Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silica precipitation with synthetic silaffin peptides

(2011) Ralph Wieneke et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Hydrosiloxane–Ti(OiPr)4: an efficient system for the reduction of primary amides into primary amines as their hydrochloride salts

(2011) Stéphane Laval et al.   TETRAHEDRON LETTERS

A Genetically Encoded ε-N-Methyl Lysine in Mammalian Cells

(2010) Dan Groff  et al.   CHEMBIOCHEM

Zinc-Catalyzed Reduction of Amides: Unprecedented Selectivity and Functional Group Tolerance

(2010) Shoubhik Das et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Characterization of Formaldehyde-Induced Cross-Links Between Amino Acids and Deoxynucleosides and Their Oligomers

(2010) Kun Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective Catalytic Reductions of Amides and Nitriles to Amines

(2010) Shoubhik Das et al.   TOPICS IN CATALYSIS

Peptidomimetics - A Versatile Route to Biologically Active Compounds

(2009) Andreas Grauer et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Practical Access to Amines by Platinum-Catalyzed Reduction of Carboxamides with Hydrosilanes: Synergy of Dual Si−H Groups Leads to High Efficiency and Selectivity

(2009) Shiori Hanada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Scaleable catalytic asymmetric Strecker syntheses of unnatural α-amino acids

(2009) Stephan J. Zuend et al.   NATURE

Solid-Phase Synthesis of Amino- and Carboxyl-Functionalized Unnatural α-Amino Acid Amides

(2009) William L. Scott et al.   ORGANIC LETTERS

A robust strategy for the preparation of libraries of metallopeptides. A new paradigm for the discovery of targeted molecular imaging and therapy agents

(2008) Andrea F. Armstrong et al.   CHEMICAL COMMUNICATIONS

One-step conversion to tertiary amines: InBr3/Et3SiH-mediated reductive deoxygenation of tertiary amides

(2008) Norio Sakai et al.   TETRAHEDRON LETTERS