A dual optical and nuclear imaging reagent for peptide labelling via disulfide bridging

Functional native disulfide bridging enables delivery of a potent, stable and targeted antibody–drug conjugate (ADC)

(2015) João P. M. Nunes et al.   CHEMICAL COMMUNICATIONS

A platform for efficient, thiol-stable conjugation to albumin's native single accessible cysteine

(2015) Mark E. B. Smith et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy

(2015) Antoine Maruani et al.   Nature Communications

Bridging Disulfides for Stable and Defined Antibody Drug Conjugates

(2014) George Badescu et al.   BIOCONJUGATE CHEMISTRY

Homogeneous Bispecifics by Disulfide Bridging

(2014) Elizabeth A. Hull et al.   BIOCONJUGATE CHEMISTRY

Aryloxymaleimides for cysteine modification, disulfide bridging and the dual functionalization of disulfide bonds

(2014) Cristina Marculescu et al.   CHEMICAL COMMUNICATIONS

Next generation maleimides enable the controlled assembly of antibody–drug conjugates via native disulfide bond bridging

(2014) Felix F. Schumacher et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Reversible protein affinity-labelling using bromomaleimide-based reagents

(2013) Ramiz I. Nathani et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A mild synthesis of N-functionalised bromomaleimides, thiomaleimides and bromopyridazinediones

(2013) Lourdes Castañeda et al.   TETRAHEDRON LETTERS

New insights into the therapeutic potential of Girk channels

(2013) Rafael Luján et al.   TRENDS IN NEUROSCIENCES

Homogeneous antibody fragment conjugation by disulfide bridging introduces ‘spinostics’

(2013) Felix F. Schumacher et al.   Scientific Reports

Development of a long acting human growth hormone analog suitable for once a week dosing

(2012) Moorthy S.S. Palanki et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Alkyne-Tag Raman Imaging for Visualization of Mobile Small Molecules in Live Cells

(2012) Hiroyuki Yamakoshi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A One-Pot Three-Component Radiochemical Reaction for Rapid Assembly of 125I-Labeled Molecular Probes

(2012) Ran Yan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

One-Pot Synthesis of an 125I-Labeled Trifunctional Reagent for Multiscale Imaging with Optical and Nuclear Techniques

(2011) Ran Yan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A New Synthetic Protocol for One-Pot Preparations of 5-Halo-1,4-disubstituted-1,2,3-triazoles

(2011) Lingjun Li et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

In Situ Maleimide Bridging of Disulfides and a New Approach to Protein PEGylation

(2011) Felix F. Schumacher et al.   BIOCONJUGATE CHEMISTRY

Bromomaleimide-Linked Bioconjugates Are Cleavable in Mammalian Cells

(2011) Paul Moody et al.   CHEMBIOCHEM

Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis

(2011) Chris P. Ryan et al.   CHEMICAL COMMUNICATIONS

Polymeric Dibromomaleimides As Extremely Efficient Disulfide Bridging Bioconjugation and Pegylation Agents

(2011) Mathew W. Jones et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides

(2010) Mark E. B. Smith et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peptide-mediated targeted drug delivery

(2010) Sumit Majumdar et al.   MEDICINAL RESEARCH REVIEWS

Bromomaleimides: new reagents for the selective and reversible modification of cysteine

(2009) Lauren M. Tedaldi et al.   CHEMICAL COMMUNICATIONS

Nanosystem drug targeting: Facing up to complex realities

(2009) Pakatip Ruenraroengsak et al.   JOURNAL OF CONTROLLED RELEASE

Agonist−Antagonist Dilemma in Molecular Imaging: Evaluation of a Monomolecular Multimodal Imaging Agent for the Somatostatin Receptor

(2007) W. Barry Edwards et al.   BIOCONJUGATE CHEMISTRY