Article
Neurosciences
Kelsey E. Zuk, Hillary L. Cansler, Jinxin Wang, Julian P. Meeks
Summary: The accessory olfactory system (AOS) is crucial for social behavior development. In male and female mice, the accessory olfactory bulb (AOB) displays plasticity in response to social experience. Internal granule cells (IGCs) in the AOB express the immediate-early gene Arc after aggression or mating. This study investigates the role of Arc-expressing IGCs in the processing of territorial aggression. Results show that these IGCs become more excitable after resident-intruder interactions and play a significant role in ramping aggression exhibited by resident male mice.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Jan Weiss, Frank Zufall
Summary: This study demonstrates that GABA(B) receptors are expressed in the accessory olfactory bulb (AOB) and primarily located at vomeronasal nerve (VN) terminals. Activation of these receptors can modulate calcium influx and glutamate release of vomeronasal sensory neurons (VSNs), resulting in the regulation of synaptic transmission in the accessory olfactory system.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2023)
Article
Neurosciences
Chase Amos, Michael A. Fox, Jianmin Su
Summary: The accessory olfactory bulb (AOB) in mammals receives input from vomeronasal sensory neurons (VSN) to detect pheromones and regulate the behaviors of animals of the same species. The molecular mechanism underlying the assembly of circuitry in the mouse AOB and the role of Collagen XIX in synaptogenesis were investigated in this study. The results showed that the loss of Collagen XIX led to defects in excitatory synapse distribution in the AOB and altered behavioral responses to pheromones in mutant mice.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2023)
Article
Immunology
M. Fernanda Palominos, Cristian Calfun, Gino Nardocci, Danissa Candia, Jorge Torres-Paz, Kathleen E. Whitlock
Summary: In the olfactory organs, a unique population of neutrophils associated with both the olfactory epithelia and the lymphatic vasculature suggests a dual olfactory-immune function.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Mateo Torres, Irene Ortiz-Leal, Andrea Ferreiro, Jose Luis Rois, Pablo Sanchez-Quinteiro
Summary: Chemical senses play a crucial role in the survival of wild mammals. This study focuses on the neuroanatomical basis of the olfactory and accessory olfactory bulbs in meerkats. The results suggest that meerkats have a well-defined accessory olfactory bulb lamination pattern and a comparable level of development in the main olfactory bulb compared to other mammals. This study supports the functionality of the olfactory and vomeronasal integrative centers in meerkats and provides important information for understanding their chemical senses.
Article
Biology
Rohini Bansal, Maximilian Nagel, Romana Stopkova, Yizhak Sofer, Tali Kimchi, Pavel Stopka, Marc Spehr, Yoram Ben-Shaul
Summary: Despite genetic variations, animals' olfactory systems are able to maintain stable representations of stimuli, providing a basis for common behaviors. Laboratory inbreeding does not always result in modifications that impact key ethological features related to wild animals.
Article
Zoology
Atsuhiro Sakuma, Zicong Zhang, Eri Suzuki, Tatsuki Nagasawa, Masato Nikaido
Summary: Traditionally, the vomeronasal organ (VNO) was believed to have originated in tetrapods, but recent studies have shown its presence in lungfish. This study examined the olfactory organ of bichir and found that the VNO and main olfactory organ (MOO) have similar functions, while the accessory olfactory organ (AOO) has an additional function for water uptake.
ZOOLOGICAL LETTERS
(2022)
Article
Ophthalmology
Navid Manafi, Fereshteh Shokri, Kevin Achberger, Masatoshi Hirayama, Melika Haji Mohammadi, Farsad Noorizadeh, Jiaxu Hong, Stefan Liebau, Takashi Tsuji, Peter M. J. Quinn, Alireza Mashaghi
Summary: Recent advances in stem cell-derived, self-organizing, three-dimensional miniature organs, such as organoids and organ chips, have shown potential in simulating the complexity of native organ structure and function. They may enhance our understanding of the physiology of different eye structures, explore unknown aspects of ophthalmic disease pathogenesis, and serve as clinically-relevant tools for evaluating ocular therapeutics.
Article
Clinical Neurology
Muhammet Sancaktar, Senguel Kocamer Sahin, Bahadir Demir, Umut Elboga, Guelcin Elboga, Abdurrahman Altindag
Summary: This study reveals that patients with bipolar disorder have increased metabolism in both the olfactory bulb and the amygdala, and there is a positive correlation between the metabolism of these two regions. This suggests that the increased metabolism in the olfactory bulb may be the main cause of hypermetabolism in the amygdala in bipolar disorder.
JOURNAL OF NEURAL TRANSMISSION
(2023)
Review
Behavioral Sciences
Rebeca Corona, Benito Ordaz, Ludivina Robles-Osorio, Ernesto Sabath, Teresa Morales
Summary: Chronic kidney disease is a multifactorial pathology that affects metabolic functions and is associated with inflammation, nutritional status, and olfactory deficits.
FRONTIERS IN INTEGRATIVE NEUROSCIENCE
(2022)
Article
Neurosciences
Nandkishore Prakash, Heidi Y. Matos, Sonia Sebaoui, Luke Tsai, Tuyen Tran, Adejimi Aromolaran, Isabella Atrachji, Nya Campbell, Meredith Goodrich, David Hernandez-Pineda, Maria Jesus Herrero, Tsutomu Hirata, Julieta Lischinsky, Wendolin Martinez, Shisui Torii, Satoshi Yamashita, Hassan Hosseini, Katie Sokolowski, Shigeyuki Esumi, Yuka Imamura Kawasawa, Kazue Hashimoto-Torii, Kevin S. Jones, Joshua G. Corbin
Summary: This study uncovers the molecular diversity of neurons in the accessory olfactory system (AOS) and reveals lineage and sex differences in patterns of connectivity.
JOURNAL OF COMPARATIVE NEUROLOGY
(2023)
Article
Anatomy & Morphology
Irene Ortiz-Leal, Mateo V. Torres, Paula R. Villamayor, Luis Eusebio Fidalgo, Ana Lopez-Beceiro, Pablo Sanchez-Quinteiro
Summary: The fox accessory olfactory bulb (AOB) shows a higher degree of morphological development compared with the dog AOB. The findings suggest that domestication may have affected the morphological structure of the dog AOB.
ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER
(2022)
Article
Biology
Lauren E. Simonitis, Christopher D. Marshall
Summary: The study on the olfactory organ of bonnethead sharks revealed different water flow velocities in different parts of the complex structure, with the medial end experiencing nearly stagnant water recirculation. The findings suggest that areas with slower water velocities have less sensory area and secondary folding, indicating they may be less sensitive to odors. Future work should investigate sensitivity differences within the olfactory rosette along the lateral-to-medial gradient.
INTEGRATIVE ORGANISMAL BIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hanife Kocakaya, Nuray Bayar Muluk, Pelin Zeynep Bekin Sarikaya
Summary: This study investigated the olfactory measurements in patients with bipolar disorder using MRI and found that the OB volume and OS depth were lower in the bipolar group compared to the control group. The corpus amygdala and left insular gyrus area were also significantly lower in the bipolar group. There were positive correlations between OB volumes and the insular gyrus areas, as well as the corpus amygdala areas. Therefore, new treatment techniques such as olfactory training may be considered for bipolar disorder patients.
Article
Ophthalmology
Bengi Ece Kurtul, Ahmet Elbeyli, Ahmet Kakac, Faruk Turgut
Summary: This study revealed lower corneal endothelial cell density, decreased superior quadrant retinal nerve fiber layer thickness, and reduced microvascular densities of optic disc in patients with ADPKD. Evaluation of corneal endothelial cell density and retinal microvasculature may be beneficial for managing these patients.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2021)