Hedgehog pathway as a potential treatment target in human cholangiocarcinoma

Inhibition of hedgehog signaling attenuates carcinogenesisin vitroand increases necrosis of cholangiocellular carcinoma

(2012) Mona El Khatib et al.   HEPATOLOGY

Sonic Hedgehog in pancreatic cancer: From bench to bedside, then back to the bench

(2012) David E. Rosow et al.   SURGERY

Review article: surgical, neo-adjuvant and adjuvant management strategies in biliary tract cancer

(2011) J. R. A. Skipworth et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Myofibroblast-derived PDGF-BB promotes hedgehog survival signaling in cholangiocarcinoma cells

(2011) Christian D. Fingas et al.   HEPATOLOGY

Combination of Hedgehog Signaling Blockage and Chemotherapy Leads to Tumor Reduction in Pancreatic Adenocarcinomas

(2011) Marcus Bahra et al.   PANCREAS

Hedgehog signaling in the liver

(2010) Alessia Omenetti et al.   JOURNAL OF HEPATOLOGY

Cisplatin plus Gemcitabine versus Gemcitabine for Biliary Tract Cancer

(2010) Juan Valle et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intrahepatic Cholangiocarcinoma

(2009) Itaru Endo et al.   ANNALS OF SURGERY

Paracrine Hedgehog Signaling in Cancer

(2009) J.-W. Theunissen et al.   CANCER RESEARCH

Hedgehog signalling: Emerging evidence for non-canonical pathways

(2009) Dagan Jenkins   CELLULAR SIGNALLING

Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production

(2009) Alessia Omenetti et al.   HEPATOLOGY

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy

(2009) Suzie J. Scales et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Intrahepatic Cholangiocarcinoma: Prognostic Factors After Surgical Resection

(2009) Alfredo Guglielmi et al.   WORLD JOURNAL OF SURGERY

Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer

(2008) G Feldmann et al.   GUT

An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer

(2008) G. Feldmann et al.   MOLECULAR CANCER THERAPEUTICS

A paracrine requirement for hedgehog signalling in cancer

(2008) Robert L. Yauch et al.   NATURE