Review
Plant Sciences
Sunil Kumar, Bikarma Singh, Ramesh Singh
Summary: Catharanthus roseus is a traditional medicinal plant used in the treatment of cancer and diabetes, containing various compounds with pharmacological activities. Research has shown that extracts and compounds from this plant exhibit potential anticancer and antidiabetic properties, but caution is needed as toxicity can occur beyond a certain limit.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Plant Sciences
Xin Wei, Chunyan Gao, Chunhao Chang, Zhonghua Tang, Dewen Li
Summary: This study found that exogenous trehalose has a positive regulatory effect on Catharanthus roseus under low-temperature stress, increasing plant chlorophyll content and antioxidant enzyme activity. However, trehalose application inhibited the accumulation of alkaloids in C. roseus. Additionally, trehalose significantly increased the expression of 4 enzyme genes involved in alkaloids metabolism.
JOURNAL OF PLANT GROWTH REGULATION
(2023)
Article
Biochemistry & Molecular Biology
Purin Candra Purnama, Leonardo Castellanos Hernandez, Robert Verpoorte
Summary: The presence and significance of endophytes in plant biosynthetic pathways is still unclear. Fungicide treatments have varying effects on plants, such as decreasing taxol content in Taxus and causing the disappearance of ergot alkaloids in Ipomoea asarifolia. Fungicides also affect the primary and secondary metabolism of plants, as observed in Narcissus pseudonarcissus cv. Carlton and Jacobaea.
Article
Biochemistry & Molecular Biology
Mahdi Yahyazadeh, Gerold Jerz, Peter Winterhalter, Dirk Selmar
Summary: Medicinal plants grown under stress conditions exhibit higher concentrations of specialized metabolites, potentially due to enhanced biosynthesis, although stress also reduces biomass gain. Study on Catharanthus roseus plants showed that alkaloid concentrations were markedly higher under drought stress, but overall alkaloid content per plant increased only in the first two weeks. High salt concentrations did not affect alkaloid concentrations but significantly decreased total alkaloid content, suggesting that both increased biosynthesis and reduced biomass contribute to stress-related concentration increase.
Review
Biotechnology & Applied Microbiology
Vyoma Mistry, Siddhi Darji, Pragya Tiwari, Abhishek Sharma
Summary: Catharanthus roseus is a medicinal plant known for biosynthesizing anticancer monoterpenoid indole alkaloids, with more than 130 bioactive compounds synthesized. Due to their cytotoxic nature, the production of these compounds is low in plants. Research has attempted to increase production through plant tissue culture and metabolic engineering.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2022)
Article
Plant Sciences
F. A. S. Hassan, E. Ali, A. Gaber, M. Fetouh, R. Mazrou
Summary: Chitosan nanoparticles show significant potential in mitigating salt stress in Catharanthus roseus by activating antioxidant defense system and inducing gene expression, leading to higher alkaloid accumulation and better protection against salinity stress.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Plant Sciences
Maneesha Mall, Karuna Shanker, Dinesh A. Nagegowda, Abdul Samad, Alok Kalra, Alok Pandey, Velusamy Sundaresan, Ashutosh K. Shukla
Summary: Plant lipocalins have various functions. A temperature-induced lipocalin (CrTIL) was studied to understand its role in maintaining cell membrane integrity and its relationship with vindoline content. The study confirmed that CrTIL is involved in maintaining membrane stability and showed an inverse relationship with vindoline content. This research provides insights into the importance of CrTIL in intracellular sequestration, storage, and viability of vindoline.
PHYSIOLOGIA PLANTARUM
(2023)
Article
Environmental Sciences
Monika Markovic, Jasna Sostaric, Antonija Kojic, Brigita Popovic, Ante Bubalo, Dejan Bosnjak, Aleksandar Stanisavljevic
Summary: The study of salinity stress in irrigated floriculture can contribute significantly to freshwater preservation. Zinnia showed sensitivity to salinity stress, while periwinkle exhibited mild tolerance up to 3 dS m(-1).
Article
Plant Sciences
Joana G. Guedes, Rogerio Ribeiro, Ines Carqueijeiro, Ana Luisa Guimaraes, Claudia Bispo, John Archer, Herlander Azevedo, Nuno A. Fonseca, Mariana Sottomayor
Summary: The mesophyll idioblasts of Catharanthus roseus are a hotspot for alkaloid accumulation and have a distinctive transcriptomic profile associated with stress responses. The transcriptome of idioblasts may hold the key to understanding the MIA pathway and increasing the levels of anticancer drugs.
JOURNAL OF EXPERIMENTAL BOTANY
(2023)
Article
Plant Sciences
Kotaro Yamamoto, Dagny Grzech, Konstantinos Koudounas, Emily Amor Stander, Lorenzo Caputi, Tetsuro Mimura, Vincent Courdavault, Sarah E. O'Connor
Summary: Researchers developed an improved VIGS method and discovered a new biosynthetic enzyme, serpentine synthase (SS), in Catharanthus roseus, which produces beta-carboline alkaloids with strong blue autofluorescence and potential pharmacological activity.
Article
Agronomy
Neda Sahi, Akbar Mostajeran, Mustafa Ghanadian
Summary: In Catharanthus roseus seedlings, potassium in the form of KNO3 increased the contents of vinblastine and vincristine, while Ascorbic acid (AsA) also had an increasing effect on these compounds. There was a positive interaction between K+ and AsA, which influenced the amounts of vinblastine, vincristine, and gene expression.
PLANT SOIL AND ENVIRONMENT
(2022)
Article
Plant Sciences
E. F. Ali, A. M. El-Shehawi, O. H. M. Ibrahim, E. Y. Abdul-Hafeez, M. M. Moussa, F. A. S. Hassan
Summary: This study is the first to demonstrate the use of chitosan nanoparticles (CSNPs) in alleviating drought stress of Catharanthus roseus by enhancing antioxidant potential and gene expression related to alkaloid biosynthesis. CSNPs increased proline accumulation and the activity of catalase (CAT) and ascorbate peroxidase (APX), reducing drought-induced oxidative stress and preserving membrane integrity. Additionally, CSNPs led to increased alkaloid accumulation and upregulated gene expression associated with alkaloid biosynthesis under drought stress.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Fanfan Li, Stephen Bordeleau, Kyung Hee Kim, Jonathan Turcotte, Benjamin Davis, Lan Liu, Stephane Bayen, Vincenzo De Luca, Mehran Dastmalchi
Summary: This study described a Catharanthus roseus mutant that accumulates high levels of monoterpenoid indole alkaloids (MIAs). The mutant exhibited stunted growth and deficiency in chlorophyll biosynthesis, along with lesion formation. The lesions were enriched in MIAs and resulted from upregulation of genes involved in the MIA pathway. Furthermore, the accumulation of akuammicine, a minor constituent of the mutant, was found to be inducible by jasmonate and may have a role in plant defense.
Article
Multidisciplinary Sciences
Jasmine Ga May Eng, Mohammadamin Shahsavarani, Daniel Patrick Smith, Josef Hajicek, Vincenzo De Luca, Yang Qu
Summary: This study discovered and characterized vindolinine synthase, an enzyme that catalyzes an unusual redox-neutral reaction, leading to alkaloid diversity. This has important implications for understanding plant specialized metabolism and alkaloid synthesis.
NATURE COMMUNICATIONS
(2022)
Article
Biotechnology & Applied Microbiology
A. Mujib, Samar Fatima, Moien Qadir Malik
Summary: The study investigated the impact of gamma ray irradiation on callus biomass growth and the yield of vincristine and vinblastine in in vitro grown tissues of Catharanthus roseus. The lower gamma irradiation levels of 20-40 Gy were found to be more effective in enriching alkaloids, while higher doses declined the yield.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2022)
Article
Plant Sciences
Sadaf Choudhary, Kaiser Iqbal Wani, M. Naeem, M. Masroor A. Khan, Tariq Aftab
Summary: Salinity stress is a major obstacle that affects crop productivity, and plants have evolved physiological and molecular mechanisms to cope with it. Polyamines play a significant role in salt tolerance mechanisms and adaptation strategies, while ion pumps and osmolytes provide protective functions during salt stress.
JOURNAL OF PLANT GROWTH REGULATION
(2023)
Article
Plant Sciences
Vikas Mangal, Milan Kumar Lal, Rahul Kumar Tiwari, Muhammad Ahsan Altaf, Salej Sood, Dharmendra Kumar, Vinay Bharadwaj, Brajesh Singh, Rajesh Kumar Singh, Tariq Aftab
Summary: Salinity stress has negative effects on plant growth and development. Reactive oxygen species, reactive nitrogen species, and reactive sulfur species play important roles in regulating ion homeostasis and salt tolerance.
JOURNAL OF PLANT GROWTH REGULATION
(2023)
Review
Environmental Sciences
Biswaranjan Behera, Mrunalini Kancheti, Md Basit Raza, Aalok Shiv, Vikas Mangal, Gajendra Rathod, Muhammad Ahsan Altaf, Awadhesh Kumar, Tariq Aftab, Ravinder Kumar, Rahul Kumar Tiwari, Milan Kumar Lal, Brajesh Singh
Summary: This review investigates the physio-biochemical and molecular responses and mechanism of boron (B) uptake under its toxic condition. It also analyzes the spatial distribution and accumulation of B in plants regulated by sugar alcohols (polyols) and provides management strategies to alleviate B toxicity. The study highlights the narrow range between essential and toxic levels of B in plants and the symptoms that occur with slight changes in B concentration in soil. It discusses the morphological, anatomical, physiological, biochemical, and molecular responses of plants to B toxicity, including impaired growth, chlorosis, and disruption of various systems in the plant.
INTERNATIONAL JOURNAL OF PHYTOREMEDIATION
(2023)
Article
Plant Sciences
Kaiser Iqbal Wani, Andleeb Zehra, Sadaf Choudhary, M. Naeem, M. Masroor A. Khan, Riyazuddeen Khan, Tariq Aftab
Summary: The foliar spray of synthetic strigolactone analog GR24 has a positive impact on the growth and artemisinin production of Artemisia annua, with 4 mu M concentration showing the best results.
JOURNAL OF PLANT GROWTH REGULATION
(2023)
Article
Plant Sciences
Rahul Kumar Tiwari, Ravinder Kumar, Milan Kumar Lal, Awadhesh Kumar, Muhammad Ahsan Altaf, Rajni Devi, Vikas Mangal, Safina Naz, Muhammad Mohsin Altaf, Abhijit Dey, Tariq Aftab
Summary: Melatonin and polyamines are widely found in plants and play crucial roles in various physiological processes and abiotic stress responses. Melatonin-induced regulation of polyamine metabolism enhances stress tolerance through activation of antioxidant enzymes and maintenance of ionic homeostasis. Melatonin-polyamine crosstalk with other hormones, such as salicylic acid, abscisic acid, and ethylene, forms a complex defense activation network. This study provides insights into the regulatory role of melatonin in polyamine metabolism and its involvement in stress tolerance mechanisms, as well as the potential hormonal crosstalk.
JOURNAL OF PLANT GROWTH REGULATION
(2023)
Review
Chemistry, Multidisciplinary
Nirjhar Bhattacharyya, Uttpal Anand, Ravi Kumar, Mimosa Ghorai, Tariq Aftab, Niraj Kumar Jha, Anushka Upamali Rajapaksha, Jochen Bundschuh, Elza Bontempi, Abhijit Dey
Summary: The use of CRISPR technology allows for the modification of plants to better remediate soil contaminated with toxic metals. This technique has been successfully applied to various crops and has identified genes related to metal absorption and tolerance. However, the efficacy of CRISPR technology is influenced by multiple factors.
ENVIRONMENTAL CHEMISTRY LETTERS
(2023)
Article
Environmental Sciences
Rukhsar Parwez, Tariq Aftab, M. Masroor A. Khan, M. Naeem
Summary: This study aimed to evaluate the potential of nickel as an oxidative stress inducer and its effects on different varieties of fenugreek. The results showed that the application of 20 mg Ni kg(-1) soil had growth-promoting effects and improved photosynthesis and enzyme activities in PEB variety. However, higher concentrations of Ni resulted in toxic effects, which were counteracted by the PEB variety through increased proline content and antioxidant enzyme activities. The tolerance to Ni in fenugreek varieties can be organized as PEB > AFg2 > AFg1 > UM185.
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2023)
Article
Plant Sciences
Umra Aqeel, Tariq Aftab, M. Masroor A. Khan, M. Naeem
Summary: Copper is a vital micronutrient for plant growth and development, but excessive accumulation in soil threatens crop yield. This study found that concentrations of Cu above 20 mg kg-1 led to toxic effects on Mentha arvensis plants, including stunted growth, inhibited photosynthesis, increased antioxidant activity, reactive oxygen species production, and decreased essential oil production. Notably, Cu supplementation at 20 mg kg-1 significantly improved all metrics examined, particularly menthol and menthyl acetate levels. These findings demonstrate the advantageous effects of Cu supplementation at moderate concentrations, but toxicity at higher concentrations for M. arvensis plants.
Article
Environmental Sciences
Umra Aqeel, Rukhsar Parwez, Tariq Aftab, M. Masroor A. Khan, M. Naeem
Summary: Copper accumulation from human activities causes pollution in agricultural land and limits crop production. This study shows that foliar supplementation of silicon dioxide nanoparticles can enhance plant growth, photosynthetic efficiency, and antioxidant machinery, while decreasing reactive oxygen species and electrolytic leakage. Specifically, Aerosil 200F proved to be the most effective in improving copper stress tolerance in plants.
ENVIRONMENTAL RESEARCH
(2023)
Article
Agricultural Engineering
Aarifa Nabi, Tariq Aftab, M. Masroor A. Khan, M. Naeem
Summary: This study explores the role of structurally-modified carrageenan in imparting resilience towards nickel-triggered phytotoxicity in Mentha arvensis L. and proves the structure-function relationship of irradiated carrageenan (ICA). The findings demonstrate that ICA, at certain concentrations, has positive effects on the growth, photosynthesis, antioxidant enzymatic activities, and quality of Mentha arvensis L.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Engineering, Environmental
Shun-Shun Chen, Xu-Xiu Chen, Tian-Yu Yang, Li Chen, Zheng Guo, Xing-Jiu Huang
Summary: A temperature-modulated sensing strategy was proposed to identify and determine BTEX compounds. Highly effective identification of BTEX was achieved using linear discrimination and convolutional neural network analyses. Additionally, quantitative analysis of concentration was accomplished by establishing the relationship between concentration and response.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Myungkyung Noh, Jeong Yeon Sim, Jisung Kim, Jee Hwan Ahn, Hye-Young Min, Jong-Uk Lee, Jong-Sook Park, Ji Yun Jeong, Jae Young Lee, Shin Yup Lee, Hyo-Jong Lee, Choon-Sik Park, Ho-Young Lee
Summary: This study reveals that chronic exposure to PM induces chronic inflammation and development of COPD by dysregulating NAD+ metabolism and subsequent SIRT1 deficiency in pulmonary macrophages. Activation of SIRT1 by resveratrol effectively mitigates PM-induced inflammation and COPD development. Targeting metabolic and epigenetic reprogramming in macrophages induced by PM is a promising strategy for COPD treatment.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Yu Liu, Linlin Qin, Yiming Qin, Tong Yang, Haoran Lu, Yulong Liu, Qiqi Zhang, Wenyan Liang
Summary: Co/NC/PAC electrode was prepared by compounding ZIF-67 with powder-activated carbon for the electrocatalytic treatment of nitrogen-containing heterocyclic compounds. The degradation efficiency of the four compounds reached 90.2-93.7% under optimal conditions, and the degradation order was pyridazine < pyrimidine < pyrazine < pyridine.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Julien Couturier, Pierre Tamba Oulare, Blanche Collin, Claire Lallemand, Isabelle Kieffer, Julien Longerey, Perrine Chaurand, Jerome Rose, Daniel Borschneck, Bernard Angeletti, Steven Criquet, Renaud Podor, Hamed Pourkhorsandi, Guilhem Arrachart, Clement Levard
Summary: This study analyzes the properties of bauxite residue samples and explores the influence of bauxite ore origin, storage conditions, and storage time. The results show that the speciation of yttrium is related to the origin of bauxite ore, while no significant variation was observed with storage conditions or aging of the residues.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Sakthinarenderan Saikumar, Ravi Mani, Mirunalini Ganesan, Inbakandan Dhinakarasamy, Thavamani Palanisami, Dharani Gopal
Summary: Microplastic contamination in marine ecosystems poses a growing concern due to its trophic transfer and negative effects on marine organisms. This study investigates the transfer and impacts of polystyrene microplastics in an estuarine food chain. The results show that microplastics can be transferred through the food chain, although the transfer rates are low. The exposed organisms exhibit stress responses, suggesting the potential risk of microplastics reaching humans through the food chain.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Review
Engineering, Environmental
Yan-Jiao Li, Ying Yuan, Wen-Bing Tan, Bei-Dou Xi, Hui Wang, Kun-Long Hui, Jia-Bao Chen, Yi-Fan Zhang, Lian-Feng Wang, Ren-Fei Li
Summary: This review investigated and analyzed the distribution, composition, and abundance of heavy metals and antibiotic resistance genes (ARGs) in landfill. The results showed that heavy metals have lasting effects on ARGs, and complexes of heavy metals and organic matter are common in landfill. This study provides a new basis to better understand the horizontal gene transfer (HGT) of ARGs in landfill.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Jessy Joseph, Ari Vaisanen, Ajay B. Patil, Manu Lahtinen
Summary: Efficient and environmentally friendly porous hybrid adsorbent beads have been developed for the removal of arsenic from drinking water. The structural tuning of the adsorbents has been shown to have a significant impact on their adsorption performance, with high crystallinity leading to increased adsorption capacity and selectivity towards As5+.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Yangyang Liu, Minhua Xiao, Kaiqin Huang, Juntao Cui, Hongli Liu, Yingxin Yu, Shengtao Ma, Xihong Liu, Meiqing Lin
Summary: This study measured the levels of phthalate metabolites in breast milk collected from mothers in southern China. The results showed that phthalates are still prevalent in the region, and breastfeeding contributes to phthalate intake in infants. However, the levels detected do not pose significant health risks to infants based on dietary exposure. The increasing exposure to certain phthalates calls for further research into their sources and potential risks.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Zhiqiang Wu, Jianxing Sun, Liting Xu, Hongbo Zhou, Haina Cheng, Zhu Chen, Yuguang Wang, Jichao Yang
Summary: Ocean depth affects microbial diversity, composition, and co-occurrence patterns of microplastic microbial communities. Deterministic processes dominate the assembly of mesopelagic plastisphere microbial communities, while stochastic processes shape the assembly of bathypelagic microbial communities. The relationships between microorganisms in the mesopelagic layer are more complex and stable, with Proteobacteria and Actinobacteriota playing important roles.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Tingting Xiao, Renjie Chen, Chen Cai, Shijie Yuan, Xiaohu Dai, Bin Dong, Zuxin Xu
Summary: Based on the efficiency of catalytic ozonation techniques in enhancing sludge dewaterability, this study investigated its effectiveness in simultaneous reduction of antibiotics and antibiotic resistance genes. The results showed that catalytic ozonation conditioning changed the distribution of antibiotics and achieved high degradation rates. It also significantly reduced the abundance of ARGs, inhibited horizontal gene transfer, and decreased the signal transduction of typical ARGs host bacteria.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Yang Deng, Xiaohong Guan
Summary: This article discusses two different development approaches for ferrate(VI) technology in water treatment, arguing that process integration is a promising method that can drive technological innovation and revolution in water treatment, achieving higher treatment efficiency, reduced costs and energy consumption, and a smaller physical footprint.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Zhe Zhang, Lu Zhang, Zhihao Huang, Yuxin Xu, Qingqing Zhao, Hongju Wang, Meiqing Shi, Xiangnan Li, Kai Jiang, Dapeng Wu
Summary: In this study, a floating catalytic foam was designed and prepared to enhance the mass transfer in immobilized photocatalysts for wastewater treatment. The floating catalytic foam could float on the water surface and establish a temperature gradient, effectively promoting the diffusion and adsorption of target molecules during the photocatalytic process.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Muhammad Nafees, Adiba Khan Sehrish, Sarah Owdah Alomrani, Linlin Qiu, Aasim Saeed, Shoaib Ahmad, Shafaqat Ali, Hongyan Guo
Summary: The accumulation of cadmium and antibiotics in edible plants and fertile soil is a worldwide problem. This study investigated the potential of zinc oxide nanoparticles to alleviate the toxicity of both cadmium and antibiotics and promote spinach growth.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Lurui Wan, Kai Wang, Yuan Chen, Zhiyong Xu, Wenbo Zhao
Summary: In this study, a low viscosity and high thermal stability SO2 absorbent with dual interacting sites was successfully synthesized. The absorbent showed the highest absorption enthalpy change and entropy change values among reported SO2 absorbents, and exhibited lower viscosity and comparable thermal stability to ILs.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Article
Engineering, Environmental
Zhengwei Zhou, Guojie Ye, Yang Zong, Zhenyu Zhao, Deli Wu
Summary: This study utilized Mo powder and STPP to enhance the performance of the sodium percarbonate system in pollutant degradation. The presence of Mo and STPP resulted in a higher degradation rate of the model pollutant SMX, with low oxidant consumption. The system generated multiple active species through a series of chain reactions at different pH values, exhibiting excellent performance towards electron-rich pollutants. Furthermore, Mo demonstrated excellent stability and reusability.
JOURNAL OF HAZARDOUS MATERIALS
(2024)