Evolutionary imprint of activation: The design principles of VSDs

The Conserved Phenylalanine in the K+ Channel Voltage-Sensor Domain Creates a Barrier with Unidirectional Effects

(2013) Christine S. Schwaiger et al.   BIOPHYSICAL JOURNAL

A gating charge interaction required for late slow inactivation of the bacterial sodium channel NavAb

(2013) Tamer M. Gamal El-Din et al.   JOURNAL OF GENERAL PHYSIOLOGY

Construction and validation of a homology model of the human voltage-gated proton channel hHV1

(2013) Kethika Kulleperuma et al.   JOURNAL OF GENERAL PHYSIOLOGY

Functional interactions of voltage sensor charges with an S2 hydrophobic plug in hERG channels

(2013) Yen May Cheng et al.   JOURNAL OF GENERAL PHYSIOLOGY

The voltage-sensing domain of a phosphatase gates the pore of a potassium channel

(2013) Cristina Arrigoni et al.   JOURNAL OF GENERAL PHYSIOLOGY

Energetic role of the paddle motif in voltage gating of Shaker K+ channels

(2013) Yanping Xu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular Bases for the Asynchronous Activation of Sodium and Potassium Channels Required for Nerve Impulse Generation

(2013) Jérôme J. Lacroix et al.   NEURON

Improved contact prediction in proteins: Using pseudolikelihoods to infer Potts models

(2013) Magnus Ekeberg et al.   PHYSICAL REVIEW E

A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel

(2013) Stephan A. Pless et al.   Nature Communications

Exploring structure-function relationships between TRP and Kv channels

(2013) Jeet Kalia et al.   Scientific Reports

Transfer of Kv3.1 Voltage Sensor Features to the Isolated Ci-VSP Voltage-Sensing Domain

(2012) Yukiko Mishina et al.   BIOPHYSICAL JOURNAL

Tuning the Voltage-Sensor Motion with a Single Residue

(2012) Jérôme J. Lacroix et al.   BIOPHYSICAL JOURNAL

Three-Dimensional Structures of Membrane Proteins from Genomic Sequencing

(2012) Thomas A. Hopf et al.   CELL

An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations

(2012) Ernesto Vargas et al.   JOURNAL OF GENERAL PHYSIOLOGY

Tracking a complete voltage-sensor cycle with metal-ion bridges

(2012) U. Henrion et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring conformational states of the bacterial voltage-gated sodium channel NavAb via molecular dynamics simulations

(2012) C. Amaral et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Voltage Gating in Potassium Channels

(2012) M. O. Jensen et al.   SCIENCE

Computing Posterior Probabilities for Score-based Alignments Using ppALIGN

(2012) Stefan Wolfsheimer et al.   Statistical Applications in Genetics and Molecular Biology

Water wires in atomistic models of the Hv1 proton channel

(2011) Mona L. Wood et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel

(2011) Boris Musset et al.   NATURE

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

Contributions of counter-charge in a potassium channel voltage-sensor domain

(2011) Stephan A Pless et al.   Nature Chemical Biology

Direct-coupling analysis of residue coevolution captures native contacts across many protein families

(2011) F. Morcos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor

(2011) J. J. Lacroix et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intermediate states of the Kv1.2 voltage sensor from atomistic molecular dynamics simulations

(2011) L. Delemotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation

(2010) Dick Wu et al.   JOURNAL OF GENERAL PHYSIOLOGY

Ion Channel Voltage Sensors: Structure, Function, and Pathophysiology

(2010) William A. Catterall   NEURON

A Gating Charge Transfer Center in Voltage Sensors

(2010) X. Tao et al.   SCIENCE

Protein Sectors: Evolutionary Units of Three-Dimensional Structure

(2009) Najeeb Halabi et al.   CELL

Structure and hydration of membranes embedded with voltage-sensing domains

(2009) Dmitriy Krepkiy et al.   NATURE

Sequential formation of ion pairs during activation of a sodium channel voltage sensor

(2009) Paul G. DeCaen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two Separate Interfaces between the Voltage Sensor and Pore Are Required for the Function of Voltage-Dependent K+ Channels

(2009) Seok-Yong Lee et al.   PLOS BIOLOGY

Conformational Changes and Slow Dynamics through Microsecond Polarized Atomistic Molecular Simulation of an Integral Kv1.2 Ion Channel

(2009) Pär Bjelkmar et al.   PLoS Computational Biology

OCTOPUS: improving topology prediction by two-track ANN-based preference scores and an extended topological grammar

(2008) Håkan Viklund et al.   BIOINFORMATICS

Structure, Function, and Modification of the Voltage Sensor in Voltage-Gated Ion Channels

(2008) Sara I. Börjesson et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Deconstructing voltage sensor function and pharmacology in sodium channels

(2008) Frank Bosmans et al.   NATURE

Identification of direct residue contacts in protein-protein interaction by message passing

(2008) M. Weigt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA