Activation of the IL-6R/Jak/Stat Pathway is Associated with a Poor Outcome in Resected Pancreatic Ductal Adenocarcinoma

The Relationship Between Tumor Inflammatory Cell Infiltrate and Outcome in Patients with Pancreatic Ductal Adenocarcinoma

(2012) Nigel B. Jamieson et al.   ANNALS OF SURGICAL ONCOLOGY

A Prospective Comparison of the Prognostic Value of Tumor- and Patient-Related Factors in Patients Undergoing Potentially Curative Surgery for Pancreatic Ductal Adenocarcinoma

(2011) Nigel B. Jamieson et al.   ANNALS OF SURGICAL ONCOLOGY

The Unholy Trinity: Inflammation, Cytokines, and STAT3 Shape The Cancer Microenvironment

(2011) Ning Li et al.   CANCER CELL

Stat3 and MMP7 Contribute to Pancreatic Ductal Adenocarcinoma Initiation and Progression

(2011) Akihisa Fukuda et al.   CANCER CELL

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

(2011) Marina Lesina et al.   CANCER CELL

STAT3 Plays a Critical Role in KRAS-Induced Pancreatic Tumorigenesis

(2011) R. B. Corcoran et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Combined Blockade of Src Kinase and Epidermal Growth Factor Receptor with Gemcitabine Overcomes STAT3-Mediated Resistance of Inhibition of Pancreatic Tumor Growth

(2011) N. S. Nagaraj et al.   CLINICAL CANCER RESEARCH

STAT3 Expression, Molecular Features, Inflammation Patterns, and Prognosis in a Database of 724 Colorectal Cancers

(2011) Teppei Morikawa et al.   CLINICAL CANCER RESEARCH

A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study

(2011) Michael J. Proctor et al.   EUROPEAN JOURNAL OF CANCER

JAKs go nuclear: Emerging role of nuclear JAK1 and JAK2 in gene expression and cell growth

(2011) Fouad A. Zouein et al.   GROWTH FACTORS

Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice

(2011) Eleni Maniati et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity and pancreatic cancer: Overview of epidemiologic evidence and biologic mechanisms

(2011) Paige M. Bracci   MOLECULAR CARCINOGENESIS

Activation of the PIK3CA/AKT Pathway Suppresses Senescence Induced by an Activated RAS Oncogene to Promote Tumorigenesis

(2011) Alyssa L. Kennedy et al.   MOLECULAR CELL

Taming the dragon: genomic biomarkers to individualize the treatment of cancer

(2011) Ian J Majewski et al.   NATURE MEDICINE

STAT3 Knockdown Reduces Pancreatic Cancer Cell Invasiveness and Matrix Metalloproteinase-7 Expression in Nude Mice

(2011) Hai dong Li et al.   PLoS One

Positive Mobilization Margins Alone Do Not Influence Survival Following Pancreatico-Duodenectomy for Pancreatic Ductal Adenocarcinoma

(2010) Nigel B. Jamieson et al.   ANNALS OF SURGERY

Novel STAT3 Phosphorylation Inhibitors Exhibit Potent Growth-Suppressive Activity in Pancreatic and Breast Cancer Cells

(2010) L. Lin et al.   CANCER RESEARCH

Nuclear Janus-Activated Kinase 2/Nuclear Factor 1-C2 Suppresses Tumorigenesis and Epithelial-to-Mesenchymal Transition by Repressing Forkhead Box F1

(2010) J. Nilsson et al.   CANCER RESEARCH

Dual Roles for Immunity in Gastrointestinal Cancers

(2010) Cristina Ferrone et al.   JOURNAL OF CLINICAL ONCOLOGY

Energy Balance, Host-Related Factors, and Cancer Progression

(2010) Stephen D. Hursting et al.   JOURNAL OF CLINICAL ONCOLOGY

Signal Transducer and Activator of Transcription-3, Inflammation, and Cancer

(2009) Bharat B. Aggarwal et al.   Annals of the New York Academy of Sciences

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

(2009) Michael Hedvat et al.   CANCER CELL

Inflammation and Cancer: IL-6 and STAT3 Complete the Link

(2009) Jacqueline Bromberg et al.   CANCER CELL

Targeting Inflammatory Pathways for Prevention and Therapy of Cancer: Short-Term Friend, Long-Term Foe

(2009) B. B. Aggarwal et al.   CLINICAL CANCER RESEARCH

Targeting the hypoxia-inducible factor (HIF) pathway in cancer

(2009) Evon Poon et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

(2009) J. P. Morton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Statistics, 2008

(2008) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Clinical Significance of Interleukin-6 (Il-6) Gene Polymorphism and Il-6 Serum Level in Pancreatic Adenocarcinoma and Chronic Pancreatitis

(2008) Renata Talar-Wojnarowska et al.   DIGESTIVE DISEASES AND SCIENCES

Toxicogenomic Analysis of Mainstream Tobacco Smoke-Exposed Mice Reveals Repression of Plasminogen Activator Inhibitor-1 Gene in Heart

(2008) Sabina Halappanavar et al.   INHALATION TOXICOLOGY

Insulin resistance, serum adiponectin, and proinflammatory markers in young subjects with the metabolic syndrome

(2008) Irina Kowalska et al.   METABOLISM-CLINICAL AND EXPERIMENTAL