Mucins in inflammatory bowel diseases and colorectal cancer

The Commensal Microbiota and Enteropathogens in the Pathogenesis of Inflammatory Bowel Diseases

(2011) Benoit Chassaing et al.   GASTROENTEROLOGY

The MUC13 cell-surface mucin protects against intestinal inflammation by inhibiting epithelial cell apoptosis

(2011) Y. H. Sheng et al.   GUT

Altered O-glycosylation profile of MUC2 mucin occurs in active ulcerative colitis and is associated with increased inflammation

(2011) Jessica M. Holmn Larsson et al.   INFLAMMATORY BOWEL DISEASES

Mucin dynamics and enteric pathogens

(2011) Michael A. McGuckin et al.   NATURE REVIEWS MICROBIOLOGY

Importance and regulation of the colonic mucus barrier in a mouse model of colitis

(2010) J. Petersson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Vaccine against MUC1 Antigen Expressed in Inflammatory Bowel Disease and Cancer Lessens Colonic Inflammation and Prevents Progression to Colitis-Associated Colon Cancer

(2010) P. L. Beatty et al.   Cancer Prevention Research

Evolutionary evidence of the effect of rare variants on disease etiology

(2010) IP Gorlov et al.   CLINICAL GENETICS

Muc1 Cell Surface Mucin Attenuates Epithelial Inflammation in Response to a Common Mucosal Pathogen

(2010) Wei Guang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of intestinal MUC17 membrane-bound mucin in inflammatory and neoplastic diseases of the colon

(2010) S. Senapati et al.   JOURNAL OF CLINICAL PATHOLOGY

An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity

(2010) R D Eri et al.   Mucosal Immunology

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa

(2010) Kirk S. B. Bergstrom et al.   PLoS Pathogens

Reduced mucin sulfonation and impaired intestinal barrier function in the hyposulfataemic NaS1 null mouse

(2009) P A Dawson et al.   GUT

Sulfation of Colonic Mucins byN-Acetylglucosamine 6-O-Sulfotransferase-2 and Its Protective Function in Experimental Colitis in Mice

(2009) Yuki Tobisawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycosyltransferase Function in Core 2-Type Protein O Glycosylation

(2009) E. L. Stone et al.   MOLECULAR AND CELLULAR BIOLOGY

Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer

(2009) Linda A. Feagins et al.   Nature Reviews Gastroenterology & Hepatology

Helicobacter pylori moves through mucus by reducing mucin viscoelasticity

(2009) J. P. Celli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MUC4 Mucin Interacts with and Stabilizes the HER2 Oncoprotein in Human Pancreatic Cancer Cells

(2008) P. Chaturvedi et al.   CANCER RESEARCH

Interaction of Muc2 and Apc on Wnt Signaling and in Intestinal Tumorigenesis: Potential Role of Chronic Inflammation

(2008) K. Yang et al.   CANCER RESEARCH

Expression of Pla2g2a prevents carcinogenesis in Muc2-deficient mice

(2008) R. J. A. Fijneman et al.   CANCER SCIENCE

Intestinal barrier dysfunction in inflammatory bowel diseases

(2008) Michael A. McGuckin et al.   INFLAMMATORY BOWEL DISEASES

Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice

(2008) Maria van der Sluis et al.   LABORATORY INVESTIGATION

Mucins in the mucosal barrier to infection

(2008) S K Linden et al.   Mucosal Immunology

Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis

(2008) Chad K Heazlewood et al.   PLOS MEDICINE

MUC1 Mucin Is a Negative Regulator of Toll-Like Receptor Signaling

(2007) Keiko Ueno et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Structure and Function of the Cell Surface (Tethered) Mucins

(2007) Christine L. Hattrup et al.   Annual Review of Physiology

Structure and Function of the Polymeric Mucins in Airways Mucus

(2007) David J. Thornton et al.   Annual Review of Physiology

Generation of ligand-receptor alliances by “SEA” module-mediated cleavage of membrane-associated mucin proteins

(2002) Daniel H. Wreschner et al.   PROTEIN SCIENCE