Article
Gastroenterology & Hepatology
Kazuhiro Mizukami, Kentaro Sugano, Tomomi Takeshima, Kazunari Murakami
Summary: H. pylori eradication therapy reduces the incidence of peptic ulcers and gastritis, but is associated with increased incidence of other chronic diseases.
WORLD JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Medicine, General & Internal
Shinsuke Yahata, Minoru Tamura, Atsushi Yamaoka, Yoshihide Fujioka, Masanobu Okayama
Summary: The Yoitoko check-up is a novel health check-up for older adults that provides positive feedback and aims to promote health through short-term behavioral changes. Four check-ups conducted at 3-month intervals showed that some participants experienced improvements in functional capacity scores.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2021)
Article
Gastroenterology & Hepatology
Ni-Na Zhang, Yi-Min Ma, Qi Sun, Liang-Liang Shi, Yin Xie, Xiao-Ping Zou
Summary: The study compared the efficacy of LCI and WLI endoscopy in evaluating MCL in patients with NERD, and found that the frequency of MCL was higher in NERD patients than in those with non-GERD. LCI was more sensitive in detecting MCL compared with WLI.
JOURNAL OF CLINICAL GASTROENTEROLOGY
(2022)
Article
Gastroenterology & Hepatology
Dag Holmberg, Giola Santoni, My Catarina von Euler-Chelpin, Martti Farkkila, Joonas H. Kauppila, John Maret-Ouda, Eivind Ness-Jensen, Jesper Lagergren
Summary: This population-based cohort study conducted in Denmark, Finland, Norway, and Sweden from 1979 to 2018 found that negative upper endoscopy in patients with GERD is associated with a significant and long-lasting decrease in both incidence and mortality of upper gastrointestinal cancer. The risk reduction persisted for at least 5 years in incidence and 10 years in mortality after a negative upper endoscopy.
Article
Public, Environmental & Occupational Health
Sumeet Lal, Trinh Xuan Thi Nguyen, Abdul-Salam Sulemana, Mostafa Saidur Rahim Khan, Yoshihiko Kadoya
Summary: Financial literacy has no significant impact on health check-up behavior in Japan, but factors such as gender, age, marital status, and smoking are significantly related to health check-up behavior.
Article
Urology & Nephrology
Chun-Yang Yu, Jie Liu, Chang-Hai Qi, Zhen-Yu Wu, Yue-Fei Xiao, Xue-Guang Zhang
Summary: This case report describes a patient with MCD associated with GIST and elevated IgE levels. It highlights the importance of considering the possibility of tumor in patients with nephrotic syndrome and elevated IgE levels, when allergic factors are ruled out.
Article
Medicine, General & Internal
Dennis Freuer, Jakob Linseisen, Christa Meisinger
Summary: This study found that childhood-onset asthma increases the risk of peptic ulcer disease, gastroesophageal reflux disease, and irritable bowel syndrome in adults, but decreases the risk of inflammatory bowel disease, especially ulcerative colitis.
Article
Computer Science, Cybernetics
Zhongzhi Xu, Weibin Cheng, Zhen Li, Gary Tse, Fengshi Jing, Wanmin Lian, Junzhang Tian, Qingpeng Zhang
Summary: This study aimed to develop a scoring system for mass screening of low bone density in women aged 50 years or older using basic body check-up items as variables. Age, BMI, SBP, glucose, and TCL were significantly associated with the risk of LBD, and the proposed scoring system had precision, recall, c-statistic, and F1-score of 0.66, 0.83, 0.73, and 0.74 respectively. Artificial neural networks showed better performance in all measurements.
IEEE TRANSACTIONS ON COMPUTATIONAL SOCIAL SYSTEMS
(2023)
Article
Multidisciplinary Sciences
Laura Diaz Hernandez, Stephanie Giezendanner, Roland Fischer, Andreas Zeller
Summary: The study aimed to investigate the expectations about check-ups of the general Swiss population. The results showed that almost half of the population expected to have yearly check-up examinations, with sex-specific interventions being most anticipated. This behavior contradicts recommendations and has implications for the rational use of healthcare resources.
Article
Health Care Sciences & Services
Zenebe Markos Lonseko, Wenju Du, Prince Ebenezer Adjei, Chengsi Luo, Dingcan Hu, Tao Gan, Linlin Zhu, Nini Rao
Summary: This paper proposes a generative adversarial learning-based semi-supervised segmentation framework for GI lesion diagnosis in endoscopic images to tackle the challenge of limited annotations. The proposed method is extensively tested on 4880 endoscopic images and achieves better results compared to current related works, confirming its effectiveness.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Editorial Material
Cell Biology
Sebastian Brandhorst, Valter D. Longo
Summary: Skipping breakfast is associated with increased overall and disease-specific mortality, potentially due to increased hunger and lower energy expenditure.
Article
Medicine, General & Internal
Kosuke Okada, Takahisa Watahiki, Kaoru Horie, Takako Takayama, Yuka Aida, Keii To, Takashi Shida, Kazunori Ishige, Hiroyuki Nishiyama, Junichi Shoda, Hideo Suzuki
Summary: FP is characterized by pancreatic fat accumulation and the development of pancreatic and metabolic complications. The severity of FP is associated with features of lifestyle-related diseases and liver steatosis. Individuals with liver steatosis are more likely to have severe FP.
Article
Cell Biology
Maurice B. Loughrey, Neil A. Shepherd
Summary: This review discusses the indications and contraindications for endoscopic biopsy of the upper gastrointestinal tract, with a focus on controversies related to Barrett's esophagus, chronic gastritis, and duodenal biopsy in celiac disease investigation. It emphasizes the importance of detailed discussions between pathologists and endoscopists, as well as accurate clinical information provided during biopsies.
Article
Medicine, General & Internal
Sophia Lionaki, Evangelos Mantios, Ioanna Tsoumbou, Smaragdi Marinaki, George Makris, George Liapis, Chrysovalantis Vergandis, Ioannis Boletis
Summary: The study found that nearly 46% of adult MCD patients experienced at least one relapse, although renal progression was rare. Younger age of onset was identified as an independent risk factor for relapse in adult MCD patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Cell Biology
Fiammetta Ravaglia, Maria Elena Melica, Maria Lucia Angelotti, Letizia De Chiara, Paola Romagnani, Laura Lasagni
Summary: Podocytopathies are a group of proteinuric glomerular disorders driven by primary podocyte injury, with various lesion patterns observed on kidney biopsy. Recent evidence suggests that these patterns represent signs of repeated injury and repair attempts, depending on the type, length, and severity of the podocyte injury, as well as the ability of parietal epithelial cells to drive repair processes.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Gastroenterology & Hepatology
Peter Konyn, Omar Alshuwaykh, Brittany B. Dennis, George Cholankeril, Aijaz Ahmed, Donghee Kim
Summary: Gallstone disease is an independent risk factor for NAFLD but is not associated with all-cause mortality in individuals with NAFLD. Screening for gallstone disease may help stratify the risk of all-cause mortality related to gallstone disease.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Editorial Material
Gastroenterology & Hepatology
Peter Lymberopoulos, Anjiya Shaikh, Nicole E. Rich, Jihane N. Benhammou, Fasiha Kanwal, George Cholankeril
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Medicine, General & Internal
Goh Eun Chung, Su Jong Yu, Jeong-Ju Yoo, Yuri Cho, Kyu-na Lee, Dong Wook Shin, Donghee Kim, Yoon Jun Kim, Jung-Hwan Yoon, Kyungdo Han, Eun Ju Cho
Summary: This study found that the MAFLD-lean and MAFLD-diabetes groups had a higher risk of all-cause and disease-specific mortality than the MAFLD-overweight/obese group. Classifying MAFLD subgroups based on metabolic phenotypes might help risk stratification of patients with MAFLD.
Article
Gastroenterology & Hepatology
Anjiya Shaikh, Karthik Goli, Tzu-Hao Lee, Nicole E. Rich, Jihane N. Benhammou, Stephanie Keeling, Donghee Kim, Aijaz Ahmed, John Goss, Abbas Rana, Amit G. Singal, Fasiha Kanwal, George Cholankeril
Summary: This study evaluated the impact of direct-acting antiviral (DAA) availability on racial and ethnic disparities in post-liver transplant (LT) survival for black patients with hepatocellular cancer (HCC). The results showed that in the DAA era, black patients had comparable 3-year survival to white patients, indicating an improvement in racial disparities with the availability of DAA therapy.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Letter
Gastroenterology & Hepatology
Donghee Kim, Brittany B. Dennis, Karn Wijarnpreecha, George Cholankeril, Aijaz Ahmed
LIVER INTERNATIONAL
(2023)
Article
Clinical Neurology
Donghee Kim, Brittany B. Dennis, George Cholankeril, Aijaz Ahmed
Summary: This study found that there is an association between depression and metabolic dysfunction-associated fatty liver disease (MAFLD) and significant fibrosis. Individuals with depression are more likely to have MAFLD and fibrosis. This association is particularly pronounced in postmenopausal women.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Letter
Gastroenterology & Hepatology
Anjiya Shaikh, Tzu-Hao Lee, Nicole E. Rich, Jihane N. Benhammou, Peter Lymberopoulos, Vatche G. Agopian, Donghee Kim, Aijaz Ahmed, Ruben Hernaez, Carl L. Berg, John Goss, Abbas Rana, Fasiha Kanwal, George Cholankeril
LIVER TRANSPLANTATION
(2023)
Letter
Gastroenterology & Hepatology
Karthik Goli, Peter Lymberopoulos, Ronald Samuel, Anjiya Shaikh, Nisha Parakadavil, Donghee Kim, Aijaz Ahmed, John A. Goss, Abbas Rana, Tzu-Hao Lee, Fasiha Kanwal, George Cholankeril
LIVER TRANSPLANTATION
(2023)
Article
Medicine, General & Internal
Donghee Kim, Karn Wijarnpreecha, Brittany B. B. Dennis, George Cholankeril, Aijaz Ahmed
Summary: According to this study, leisure-time and transportation-related physical activity that meets the guidelines (>= 150 min/week) is associated with a lower risk of all-cause and cardiovascular mortality in individuals with nonalcoholic fatty liver disease (NAFLD), while sedentary behavior is linked to an increased risk of all-cause and cardiovascular mortality.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Pojsakorn Danpanichkul, Pinyada Moolkaew, Yatawee Kanjanakot, Natchaya Polpichai, Aunchalee Jaroenlapnopparat, Donghee Kim, Frank J. Lukens, Wahid Wassef, Michael B. Fallon, Vincent L. Chen, Rashid Lui, Karn Wijarnpreecha
Summary: This study aims to fill the research gap on early-onset colorectal cancer (CRC) in the Asia-Pacific region. The findings reveal a significant increase in early-onset CRC incidence, particularly in the Western Pacific region. Additionally, in Southeast Asia, the mortality rate is higher in females than males.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Kasey Moss, Brittany B. Dennis, Leen Naji, Aijaz Ahmed, Donghee Kim
Summary: This study investigated the effects of bilirubin levels on mortality risk among NAFLD patients. The results showed that higher bilirubin levels were associated with a lower risk of all-cause mortality, as well as cardiovascular and cancer-related mortality, in individuals with NAFLD.
JOURNAL OF GASTROINTESTINAL AND LIVER DISEASES
(2023)
Article
Gastroenterology & Hepatology
Donghee Kim, Richie Manikat, George Cholankeril, Aijaz Ahmed
Summary: We examined the changes in liver cancer-related mortality during the COVID-19 pandemic. The age-standardized mortality from hepatocellular carcinoma (HCC) showed a steady decrease, while the mortality from nonalcoholic fatty liver disease and alcohol-related liver disease demonstrated a linear increase. The mortality from intrahepatic cholangiocarcinoma (ICC) also showed a linear increase. The decline in HCC-related mortality can be attributed to a decrease in mortality caused by viral hepatitis.
LIVER INTERNATIONAL
(2023)
Article
Medicine, General & Internal
Pojsakorn Danpanichkul, Siwanart Kongarin, Sarunpakorn Permpatdechakul, Natchaya Polpichai, Kwanjit Duangsonk, Worapaka Manosroi, Nathorn Chaiyakunapruk, Omar Y. Mousa, Donghee Kim, Vincent L. Chen, Karn Wijarnpreecha
Summary: The burden of nonalcoholic fatty liver disease (NAFLD) is increasing among elderly populations in the Asia-Pacific region, emphasizing the need for timely intervention.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Anshul Bhatnagar, Sameer Prakash, Peter Lymberopoulos, Cameron Goff, Anjiya Shaikh, Donghee Kim, Aijaz Ahmed, Carl Berg, Susanna Naggie, Fasiha Kanwal, George Cholankeril, Tzu-Hao Lee
Summary: The study evaluated the survival rate of patients who received liver transplants from donors with positive hepatitis B surface antigens (HBsAg+). Data from the United Network for Organ Sharing registry was used to compare the post-transplant survival of patients who received HBsAg+ livers with those who received livers from other types of donors. The results showed that there were no statistical differences in survival rates between patients who received HBsAg+ livers and those who received livers from other types of donors.
AMERICAN JOURNAL OF TRANSPLANTATION
(2023)
Article
Gastroenterology & Hepatology
Donghee Kim, Richie Manikat, George Cholankeril, Aijaz Ahmed
Summary: In men, low total testosterone levels and increasing T/E2 ratio were associated with higher odds of NAFLD, while decreasing SHBG levels were independently associated with increased risk of NAFLD in both men and postmenopausal women. Increasing FAI was also independently associated with NAFLD, with a dose-dependent inverse association between T/E2 ratio and NAFLD.
LIVER INTERNATIONAL
(2023)