Association of genes involved in bile acid synthesis with the progression of primary biliary cirrhosis in Japanese patients

Ursodeoxycholic acid in cholestasis: linking action mechanisms to therapeutic applications

(2011) Marcelo G. Roma et al.   CLINICAL SCIENCE

A Klothoβ Variant Mediates Protein Stability and Associates With Colon Transit in Irritable Bowel Syndrome With Diarrhea

(2011) Banny S. Wong et al.   GASTROENTEROLOGY

Genetic polymorphisms in CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliary cirrhosis in Japanese patients

(2011) Yoshihiro Aiba et al.   JOURNAL OF GASTROENTEROLOGY

Promoter variant −204A > C of the cholesterol 7α-hydroxylase gene: Association with response to plant sterols in humans and increased transcriptional activity in transfected HepG2 cells

(2010) Isabel De Castro-Orós et al.   CLINICAL NUTRITION

Analysis of HLA-DRB1 polymorphisms in Japanese patients with primary biliary cirrhosis (PBC): The HLA-DRB1polymorphism determines the relative risk of antinuclear antibodies for disease progression in PBC

(2010) Minoru Nakamura et al.   HEPATOLOGY RESEARCH

A polymorphism in the integrin αV subunit gene affects the progression of primary biliary cirrhosis in Japanese patients

(2010) Tatsuo Inamine et al.   JOURNAL OF GASTROENTEROLOGY

Association analysis of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients

(2010) Satoru Joshita et al.   JOURNAL OF HEPATOLOGY

Primary biliary cirrhosis: A 2010 update

(2010) Raoul Poupon   JOURNAL OF HEPATOLOGY

Sustained upregulation of sodium taurocholate cotransporting polypeptide and bile salt export pump and downregulation of cholesterol 7α-hydroxylase in the liver of patients with end-stage primary biliary cirrhosis

(2010) Yasuaki Takeyama et al.   Medical Molecular Morphology

Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis

(2010) Gideon M Hirschfield et al.   NATURE GENETICS

Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis

(2010) Xiangdong Liu et al.   NATURE GENETICS

The potential influence of genetic variants in genes along bile acid and bile metabolic pathway on blood cholesterol levels in the population

(2009) Yingchang Lu et al.   ATHEROSCLEROSIS

Nuclear receptors as therapeutic targets in cholestatic liver diseases

(2009) Gernot Zollner et al.   BRITISH JOURNAL OF PHARMACOLOGY

Primary biliary cirrhosis

(2009) Keith D. Lindor et al.   HEPATOLOGY

Bile acids: regulation of synthesis

(2009) John Y. L. Chiang   JOURNAL OF LIPID RESEARCH

Primary Biliary Cirrhosis Associated withHLA, IL12A,andIL12RB2Variants

(2009) Gideon M. Hirschfield et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bile-acid-induced cell injury and protection

(2009) Maria J Perez et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Primary Biliary Cirrhosis Is Associated With a Genetic Variant in the 3′ Flanking Region of the CTLA4 Gene

(2008) Brian D. Juran et al.   GASTROENTEROLOGY

Human leukocyte antigen polymorphisms in italian primary biliary cirrhosis: A multicenter study of 664 patients and 1992 healthy controls

(2008) Pietro Invernizzi et al.   HEPATOLOGY

High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis

(2008) Frank G. Schaap et al.   HEPATOLOGY

Genetic factors of susceptibility and of severity in primary biliary cirrhosis

(2008) Raoul Poupon et al.   JOURNAL OF HEPATOLOGY