Regulation of anergy-related ubiquitin E3 ligase, GRAIL, in murine models of colitis and patients with Crohn’s disease

Cutting Edge: The Transmembrane E3 Ligase GRAIL Ubiquitinates the Costimulatory Molecule CD40 Ligand during the Induction of T Cell Anergy

(2014) N. B. Lineberry et al.   JOURNAL OF IMMUNOLOGY

Diet, microbes, and host genetics: the perfect storm in inflammatory bowel diseases

(2013) Vanessa Leone et al.   JOURNAL OF GASTROENTEROLOGY

Characteristics of Japanese inflammatory bowel disease susceptibility loci

(2013) Yoshiaki Arimura et al.   JOURNAL OF GASTROENTEROLOGY

Update on biologic pathways in inflammatory bowel disease and their therapeutic relevance

(2012) Matthew J. Hamilton et al.   JOURNAL OF GASTROENTEROLOGY

Use of Non-Amplified RNA Samples for Microarray Analysis of Gene Expression

(2012) Hiroko Sudo et al.   PLoS One

Regulation of Homeostasis and Inflammation in the Intestine

(2011) Thomas T. MacDonald et al.   GASTROENTEROLOGY

GRAIL: a unique mediator of CD4 T-lymphocyte unresponsiveness

(2010) Chan C. Whiting et al.   FEBS Journal

The E3 Ubiquitin Ligase GRAIL Regulates T Cell Tolerance and Regulatory T Cell Function by Mediating T Cell Receptor-CD3 Degradation

(2010) Roza I. Nurieva et al.   IMMUNITY

Naive CD4 T Cell Proliferation Is Controlled by Mammalian Target of Rapamycin Regulation of GRAIL Expression

(2009) Jack T. Lin et al.   JOURNAL OF IMMUNOLOGY

The Transmembrane E3 Ligase GRAIL Ubiquitinates and Degrades CD83 on CD4 T Cells

(2009) L. L. Su et al.   JOURNAL OF IMMUNOLOGY

How do Regulatory T Cells Work?

(2009) A. Corthay   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Upregulation of GRAIL is associated with remission of ulcerative colitis

(2008) Satoshi Egawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Recurrent superantigen exposurein vivoleads to highly suppressive CD4+CD25+and CD4+CD25-T cells with anergic and suppressive genetic signatures

(2008) J. M. Schartner et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells

(2008) Lasse Sinkkonen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY