Article
Biochemistry & Molecular Biology
Juan Wan, Meiyan Feng, Wenjing Pan, Xin Zheng, Xinya Xie, Baozhu Hu, Cuiqin Teng, Yingzi Wang, Zhonghua Liu, Jianhua Wu, Shuxian Cai
Summary: Tea has a significant inhibitory effect on the formation of aging-related amyloid, with black tea and dark tea showing antioxidant and amyloid formation inhibitory effects, while fully fermented teas exhibit better inhibitory effects on amyloid formation in vivo than green tea. The mechanism of action involves antioxidation, anti-inflammatory effects, and improvement of lipid metabolism.
Article
Food Science & Technology
Weilan Gao, Na Zhang, Shuyi Li, Shuyao Li, Shiyu Zhu, Xin Cong, Shuiyuan Cheng, Francisco J. Barba, Zhenzhou Zhu
Summary: Pulsed electric fields (PEF) and ultrasonic-assisted extraction (UE) were used to improve the extraction performance of selenium-enriched tea polysaccharides (Se-TPSs) at mild conditions. The optimal extraction process was found to be PEF2+CE2, which significantly increased the selenium content and antioxidant activity.
Review
Plant Sciences
Mursleen Yasin, Adnan Younis, Talha Javed, Ahsan Akram, Muhammad Ahsan, Rubab Shabbir, Muhammad Moaaz Ali, Ayesha Tahir, Enas M. El-Ballat, Mohamed S. Sheteiwy, Reda Helmy Sammour, Christophe Hano, Fahad A. Alhumaydhi, Mohamed A. El-Esawi
Summary: Tea tree oil from the Melaleuca genus, particularly Melaleuca bracteata and Melaleuca alternifolia, contains terpinen-4-ol and 1-8 cineole which have antioxidant and antimicrobial properties. It shows bactericidal effects against various bacterial species as well as effectiveness against fungal strains. Tea tree oil also has potential as an organic fungicide, herbicide, and insecticide in agriculture, and can be used as a natural antimicrobial and preservative agent in the food and pharmaceutical industries.
Article
Biochemistry & Molecular Biology
Gang Xiang, Huaping Sun, Yinyin Chen, Hongrui Guo, Yong Liu, Yunchun Li, Changfang Lu, Xianxiang Wang
Summary: Four polysaccharides (GTPS, OTPS, BTPS, and DTPS) were extracted from different types of tea and studied for their properties and effects. They showed significant differences in structure and composition. BTPS demonstrated higher antioxidant and hypoglycemic activities, controlling levels of blood glucose and improving liver function in diabetic mice.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Jiayi Zhao, Ziyue Xu, Peizhong Gao, Xu Liu
Summary: The present study investigated the essential oil composition and biological effects of Liparis nervosa grown in China, including antioxidant and acetylcholinesterase inhibitory activities. The essential oil was rich in various compounds, with methyl (9E,11E)-octadeca-9,11-dienoate being the most abundant. The essential oil exhibited moderate antioxidant capacity and showed potential as an acetylcholinesterase inhibitor. This study provides valuable insights into the chemical composition and potential uses of L. nervosa essential oil.
Article
Chemistry, Applied
Shiyang Zhou, Gangliang Huang, Hualiang Huang
Summary: In this study, purified polysaccharides were extracted from fresh onions using hot water extraction, protein removal, and dialysis treatment. The structure of onion polysaccharides was confirmed using various NMR techniques. Antioxidant activities of onion polysaccharide and its derivatives were tested in vitro, showing good antioxidant activity, with phosphorylated polysaccharide demonstrating similar activity to the positive control Vc.
Article
Immunology
Guokun Yang, Xiaomin Liang, Jihong Hu, Chengquan Li, Wenpan Hu, Keke Li, Xulu Chang, Yanmin Zhang, Xindang Zhang, Yawei Shen, Xiaolin Meng
Summary: Tea polysaccharides can improve the antioxidant capacity, lipid metabolism, and immunity of common carp.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Rujie Shi, Min Gong, Yanxin Li, Nong Zhou
Summary: As a traditional Chinese medicine and functional food, Polygonatum sibiricum contains bioactive compounds with multiple biological activities. The ethanol extract exhibited the best antioxidant activity and could ameliorate hepatic oxidative stress and reduce blood glucose levels. The extract also increased the activity of antioxidant enzymes and inhibited the activity of alpha-glucosidase.
JOURNAL OF FOOD BIOCHEMISTRY
(2023)
Article
Plant Sciences
Aminu Shehu Abubakar, Xiaoyu Huang, Ziggiju Mesenbet Birhanie, Gang Gao, Xinkang Feng, Chunming Yu, Ping Chen, Jikang Chen, Kunmei Chen, Xiaofei Wang, Aiguo Zhu
Summary: Apocynum hendersonii is a medicinal plant with potential health benefits due to its rich bioactive components. This study evaluated the reactivity and composition of different solvent extracts of A. hendersonii leaves. The extracts were found to contain important bioactive constituents such as phenols, flavonoids, and polysaccharides. Methanol extract showed the highest flavonoid content and antioxidant capacity, while ethanol extract exhibited the strongest antibacterial activity and inhibition of enzymes. Principal component analysis indicated a positive correlation between constituents, bioactivities, and extracts. These findings suggest that A. hendersonii can be a valuable natural source of antimicrobial and antioxidant compounds with potential applications in pharmaceutical and food industries.
Article
Biochemistry & Molecular Biology
Shuai Yuan, Pei-Yu Dong, Hao-Hai Ma, Sheng-Lin Liang, Long Li, Xi-Feng Zhang
Summary: In this study, the synthesis parameters of the lotus root polysaccharide iron complex (LRPF) were determined and optimized. LRPF showed good stability and exhibited antioxidant activity in vitro and in vivo. Furthermore, LRPF effectively treated iron deficiency anemia in model mice and reduced the perniciousness caused by iron deficiency through regulating steroid hormone biosynthesis.
Article
Biochemistry & Molecular Biology
Yin Zhou, Weiya Liu, Wendan Cao, Yong Cheng, Zhong Liu, Xiaoqiang Chen
Summary: This study evaluated the effect of hydrophobic property on the antibacterial activities of green tea polysaccharide conjugates (gTPCs) against Escherichia coli. It was found that gTPCs with higher hydrophobicity exhibited stronger antibacterial activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Huifang Wang, Meiyu Yuan, Gaoheng Li, Yuxin Tao, Xuanyu Wang, Sheng Ke, Min Zhuang, Anqi Wang, Zhongkai Zhou
Summary: This research characterized the structure of Cyperus esculentus polysaccharide (CEP) and its acetylated form (ACEP), and investigated the effects of acetylation on various properties. The results showed that both CEP and ACEP were heteropolysaccharides consisting of multiple sugars. Acetylation improved thermal stability and exhibited greater antioxidant activity. Furthermore, CEP and ACEP protected cells against inflammation. This study highlights the potential of C. esculentus for the functional food industry.
Article
Biochemistry & Molecular Biology
Jin-Hong Ma, Dan Hu, Lu-Lu Deng, Jiang Li, Xiao-Jiang Hao, Shu-Zhen Mu
Summary: Four new pentacyclic triterpenoids were isolated from Sabiadiscolor Dunn for the first time, along with eleven known ones. Their structures were identified and characterized, and their alpha-glycosidase inhibitory activities were evaluated. Compounds 1, 3, 8, 9, 13, and 15 showed remarkable activities, indicating a potential structure-activity relationship.
Article
Biochemistry & Molecular Biology
Nannan Liu, Mengyin Chen, Juanna Song, Yuanyuan Zhao, Pin Gong, Xuefeng Chen
Summary: The polysaccharides of Auricularia auricula (AAP) have been found to improve type 2 diabetes by altering the gut microbiota in mice. AAP intervention can lower blood glucose levels, improve glucose tolerance, and reduce oxidative stress injury. Furthermore, AAP can regulate the abundance of beneficial and pathogenic bacteria, influencing the structure of the gut microbiota.
Article
Chemistry, Multidisciplinary
Hitoshi Kamauchi, Momoka Hirata, Koichi Takao, Yoshiaki Sugita
Summary: The first total synthesis of isoindolinone (+/-)-en-tonalactam A (6) was achieved in 14 steps from commercially available 5-bromovanillin via benzophenone intermediates. The inhibitory activities of the synthesized compounds on monoamine oxidase A and B were tested, and isoindolinone derivative 30 showed inhibitory effects on both MAO-A and B.