The Ataxia Telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondaryVκ-to-Jκrearrangements

The Response to and Repair of RAG-Mediated DNA Double-Strand Breaks

(2012) Beth A. Helmink et al.   Annual Review of Immunology

A Dual Interaction between the DNA Damage Response Protein MDC1 and the RAG1 Subunit of the V(D)J Recombinase

(2012) Gideon Coster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual-reactive B cells are autoreactive and highly enriched in the plasmablast and memory B cell subsets of autoimmune mice

(2012) Emilie M. Fournier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

V(D)J Recombination: Mechanisms of Initiation

(2011) David G. Schatz et al.   Annual Review of Genetics

RAG-induced DNA double-strand breaks signal through Pim2 to promote pre–B cell survival and limit proliferation

(2011) Jeffrey J. Bednarski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ATM controls meiotic double-strand-break formation

(2011) Julian Lange et al.   NATURE

CTCF-binding elements mediate control of V(D)J recombination

(2011) Chunguang Guo et al.   NATURE

Allelic exclusion of immunoglobulin genes: models and mechanisms

(2010) Christian Vettermann et al.   IMMUNOLOGICAL REVIEWS

Antigen Receptor Allelic Exclusion: An Update and Reappraisal

(2010) B. L. Brady et al.   JOURNAL OF IMMUNOLOGY

H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes

(2010) Beth A. Helmink et al.   NATURE

Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination

(2009) Bu Yin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Formation of Dynamic γ-H2AX Domains along Broken DNA Strands Is Distinctly Regulated by ATM and MDC1 and Dependent upon H2AX Densities in Chromatin

(2009) Velibor Savic et al.   MOLECULAR CELL

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

(2009) Susannah L Hewitt et al.   NATURE IMMUNOLOGY

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development

(2009) Stephen Malin et al.   NATURE IMMUNOLOGY

Regulation of Immunoglobulin Light-Chain Recombination by the Transcription Factor IRF-4 and the Attenuation of Interleukin-7 Signaling

(2008) Kristen Johnson et al.   IMMUNITY

DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes

(2008) Andrea L. Bredemeyer et al.   NATURE

Foxo1 directly regulates the transcription of recombination-activating genes during B cell development

(2008) Rupesh H Amin et al.   NATURE IMMUNOLOGY