A Dual Interaction between the DNA Damage Response Protein MDC1 and the RAG1 Subunit of the V(D)J Recombinase

H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes

(2010) Beth A. Helmink et al.   NATURE

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks

(2010) Shan Zha et al.   NATURE

Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination

(2010) G. J. Grundy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Armadillo-repeat protein functions: questions for little creatures

(2010) Rita Tewari et al.   TRENDS IN CELL BIOLOGY

The roles of the RAG1 and RAG2 “non-core” regions in V(D)J recombination and lymphocyte development

(2009) Jessica M. Jones et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair

(2009) R. Scott Williams et al.   CELL

A Supramodular FHA/BRCT-Repeat Architecture Mediates Nbs1 Adaptor Function in Response to DNA Damage

(2009) Janette Lloyd et al.   CELL

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites

(2009) Sairei So et al.   JOURNAL OF CELL BIOLOGY

Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination

(2009) Bu Yin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks

(2009) Beth A. Helmink et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

(2008) J Ross Chapman et al.   EMBO REPORTS

Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin

(2008) Fredrik Melander et al.   JOURNAL OF CELL BIOLOGY

Constitutive phosphorylation of MDC1 physically links the MRE11–RAD50–NBS1 complex to damaged chromatin

(2008) Christoph Spycher et al.   JOURNAL OF CELL BIOLOGY

Lymphocyte-Specific Compensation for XLF/Cernunnos End-Joining Functions in V(D)J Recombination

(2008) Gang Li et al.   MOLECULAR CELL

Evidence for Ku70/Ku80 association with full-length RAG1

(2008) Prafulla Raval et al.   NUCLEIC ACIDS RESEARCH

MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks

(2008) L. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA