Bcl11a is essential for lymphoid development and negatively regulates p53

Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development

(2012) A. John et al.   DEVELOPMENT

Runx1–Cbfβ facilitates early B lymphocyte development by regulating expression of Ebf1

(2012) Wooseok Seo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The transcription factor Lyl-1 regulates lymphoid specification and the maintenance of early T lineage progenitors

(2012) Fabian Zohren et al.   NATURE IMMUNOLOGY

p53-Dependent Transcriptional Responses to Interleukin-3 Signaling

(2012) Anissa M. Jabbour et al.   PLoS One

Identification of the earliest NK-cell precursor in the mouse BM

(2011) S. Carotta et al.   BLOOD

The multifunctional role of EKLF/KLF1 during erythropoiesis

(2011) M. Siatecka et al.   BLOOD

Identification of the earliest natural killer cell-committed progenitor in murine bone marrow

(2011) J. W. Fathman et al.   BLOOD

Control of B Cell Development by the Histone H2A Deubiquitinase MYSM1

(2011) Xiao-Xia Jiang et al.   IMMUNITY

A critical role for TCF-1 in T-lineage specification and differentiation

(2011) Brittany Nicole Weber et al.   NATURE

Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death

(2011) Domagoj Vucic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Critical roles for c-Myb in lymphoid priming and early B-cell development

(2010) K. T. Greig et al.   BLOOD

Transcription control of early B cell differentiation

(2010) Elizabeth M Mandel et al.   CURRENT OPINION IN IMMUNOLOGY

Transcriptional silencing of  -globin by BCL11A involves long-range interactions and cooperation with SOX6

(2010) J. Xu et al.   GENES & DEVELOPMENT

Transcription Factor Miz-1 Is Required to Regulate Interleukin-7 Receptor Signaling at Early Commitment Stages of B Cell Differentiation

(2010) Christian Kosan et al.   IMMUNITY

Early B Cell Factor 1 Regulates B Cell Gene Networks by Activation, Repression, and Transcription- Independent Poising of Chromatin

(2010) Thomas Treiber et al.   IMMUNITY

The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

(2010) Sebastian Carotta et al.   IMMUNITY

Critical roles of Bcl11b in T-cell development and maintenance of T-cell identity

(2010) Pentao Liu et al.   IMMUNOLOGICAL REVIEWS

Multilayered specification of the T-cell lineage fate

(2010) Ellen V. Rothenberg et al.   IMMUNOLOGICAL REVIEWS

Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment

(2010) Yohei Morita et al.   JOURNAL OF EXPERIMENTAL MEDICINE

KLF1 regulates BCL11A expression and γ- to β-globin gene switching

(2010) Dewang Zhou et al.   NATURE GENETICS

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

(2010) Yin C Lin et al.   NATURE IMMUNOLOGY

Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development

(2010) Sergei Doulatov et al.   NATURE IMMUNOLOGY

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

(2010) I. Beerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compound haploinsufficiencies ofEbf1andRunx1genes impede B cell lineage progression

(2010) Kara Lukin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reprogramming of T Cells to Natural Killer-Like Cells upon Bcl11b Deletion

(2010) P. Li et al.   SCIENCE

An Early T Cell Lineage Commitment Checkpoint Dependent on the Transcription Factor Bcl11b

(2010) L. Li et al.   SCIENCE

An Essential Developmental Checkpoint for Production of the T Cell Lineage

(2010) T. Ikawa et al.   SCIENCE

The p53 orchestra: Mdm2 and Mdmx set the tone

(2010) Mark Wade et al.   TRENDS IN CELL BIOLOGY

Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity

(2009) R. Mansson et al.   BLOOD

p53 Regulates Hematopoietic Stem Cell Quiescence

(2009) Yan Liu et al.   Cell Stem Cell

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

(2009) M. A. Inlay et al.   GENES & DEVELOPMENT

Genome-wide Lineage-Specific Transcriptional Networks Underscore Ikaros-Dependent Lymphoid Priming in Hematopoietic Stem Cells

(2009) Samuel Yao-Ming Ng et al.   IMMUNITY

Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c

(2009) Sandra Stehling-Sun et al.   NATURE IMMUNOLOGY

A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene

(2008) B. Yin et al.   BLOOD

Pbx1 Regulates Self-Renewal of Long-Term Hematopoietic Stem Cells by Maintaining Their Quiescence

(2008) Francesca Ficara et al.   Cell Stem Cell

E2A Proteins Promote Development of Lymphoid-Primed Multipotent Progenitors

(2008) Sheila Dias et al.   IMMUNITY

Instructive Role of the Transcription Factor E2A in Early B Lymphopoiesis and Germinal Center B Cell Development

(2008) Kyongrim Kwon et al.   IMMUNITY

Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros

(2008) Damien Reynaud et al.   NATURE IMMUNOLOGY

Foxo1 directly regulates the transcription of recombination-activating genes during B cell development

(2008) Rupesh H Amin et al.   NATURE IMMUNOLOGY

Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation

(2008) Hart S Dengler et al.   NATURE IMMUNOLOGY

Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific RepressorBCL11A

(2008) Vijay G. Sankaran et al.   SCIENCE