The transcription factor Lyl-1 regulates lymphoid specification and the maintenance of early T lineage progenitors

A new allele of Lyl1 confirms its important role in hematopoietic stem cell function

(2011) George P. Souroullas et al.   GENESIS

Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activation

(2011) Tarik Möröy et al.   SEMINARS IN IMMUNOLOGY

Combinatorial Transcriptional Control In Blood Stem/Progenitor Cells: Genome-wide Analysis of Ten Major Transcriptional Regulators

(2010) Nicola K. Wilson et al.   Cell Stem Cell

Multilayered specification of the T-cell lineage fate

(2010) Ellen V. Rothenberg et al.   IMMUNOLOGICAL REVIEWS

The expansion of T-cells and hematopoietic progenitors as a result of overexpression of the lymphoblastic leukemia gene, Lyl1 can support leukemia formation

(2010) Georgi L. Lukov et al.   LEUKEMIA RESEARCH

Gfi1 Expression Is Controlled by Five Distinct Regulatory Regions Spread over 100 Kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 Acting as Upstream Regulators in Early Hematopoietic Cells

(2010) N. K. Wilson et al.   MOLECULAR AND CELLULAR BIOLOGY

CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus

(2009) A. Krueger et al.   BLOOD

Adult Hematopoietic Stem and Progenitor Cells Require Either Lyl1 or Scl for Survival

(2009) George P. Souroullas et al.   Cell Stem Cell

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

(2009) M. A. Inlay et al.   GENES & DEVELOPMENT

Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci

(2009) Kristina Beck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors

(2009) Craig L. Semerad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of Notch-dependent T-cell leukemia by deregulated Rap1 signaling

(2008) S.-F. Wang et al.   BLOOD

The Signaling Protein Wnt4 Enhances Thymopoiesis and Expands Multipotent Hematopoietic Progenitors through β-Catenin-Independent Signaling

(2008) Isabelle Louis et al.   IMMUNITY

E2A Proteins Promote Development of Lymphoid-Primed Multipotent Progenitors

(2008) Sheila Dias et al.   IMMUNITY