Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors

A Common Molecular Basis for Exogenous and Endogenous Cannabinoid Potentiation of Glycine Receptors

(2012) W. Xiong et al.   JOURNAL OF NEUROSCIENCE

Chronic Pain States: Pharmacological Strategies to Restore Diminished Inhibitory Spinal Pain Control

(2011) Hanns Ulrich Zeilhofer et al.   Annual Review of Pharmacology and Toxicology

Cannabinoids for treatment of chronic non-cancer pain; a systematic review of randomized trials

(2011) Mary E. Lynch et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Allosteric modulation of glycine receptors

(2011) Gonzalo E. Yevenes et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia

(2011) Wei Xiong et al.   Nature Chemical Biology

Inhibiting neuropathic pain

(2011) Charlotte Harrison   NATURE REVIEWS DRUG DISCOVERY

Molecular Sites for the Positive Allosteric Modulation of Glycine Receptors by Endocannabinoids

(2011) Gonzalo E. Yévenes et al.   PLoS One

Cannabinoid CB1 receptor facilitation of substance P release in the rat spinal cord, measured as neurokinin 1 receptor internalization

(2010) Guohua Zhang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Serotonin receptor 1A–modulated phosphorylation of glycine receptor α3 controls breathing in mice

(2010) Till Manzke et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of Class II Histone Deacetylases in the Spinal Cord Attenuates Inflammatory Hyperalgesia

(2010) Guang Bai et al.   Molecular Pain

Lack of positive allosteric modulation of mutated α1S267I glycine receptors by cannabinoids

(2010) Nilufar Foadi et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Examining the roles of cannabinoids in pain and other therapeutic indications: a review

(2009) Dana Turcotte et al.   EXPERT OPINION ON PHARMACOTHERAPY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Animal models of pain: progress and challenges

(2009) Jeffrey S. Mogil   NATURE REVIEWS NEUROSCIENCE

Modulation of Glycine Receptor Function by the Synthetic Cannabinoid HU210

(2009) Reyhan Demir et al.   PHARMACOLOGY

The Nonpsychotropic Cannabinoid Cannabidiol Modulates and Directly Activates Alpha-1 and Alpha-1-Beta Glycine Receptor Function

(2009) Jörg Ahrens et al.   PHARMACOLOGY

Spinal Endocannabinoids and CB1 Receptors Mediate C-Fiber-Induced Heterosynaptic Pain Sensitization

(2009) A. J. Pernia-Andrade et al.   SCIENCE

Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

(2009) Angelo A. Izzo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A selective role for α3 subunit glycine receptors in inflammatory pain

(2009) Victoria L. Harvey   Frontiers in Molecular Neuroscience

Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine

(2008) Zhe Yang et al.   BIOCHEMICAL PHARMACOLOGY

Residual Dipolar Coupling Measurements of Transmembrane Proteins Using Aligned Low-qBicelles and High-Resolution Magic Angle Spinning NMR Spectroscopy

(2008) Christian G. Canlas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY

Positive allosteric modulatory effects of ajulemic acid at strychnine-sensitive glycine α1- and α1β-receptors

(2008) Jörg Ahrens et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury

(2008) Yun Guan et al.   PAIN