Allosteric modulation of glycine receptors

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

(2011) Hugues Nury et al.   NATURE

Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia

(2011) Wei Xiong et al.   Nature Chemical Biology

A glycine residue essential for high ivermectin sensitivity in Cys-loop ion channel receptors

(2010) Timothy Lynagh et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Identification of Novel Specific Allosteric Modulators of the Glycine Receptor Using Phage Display

(2010) Megan E. Tipps et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Requirements for Ethanol Differential Allosteric Modulation of Glycine Receptors Based on Selective Gβγ Modulation

(2010) Gonzalo E. Yevenes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serotonin receptor 1A–modulated phosphorylation of glycine receptor α3 controls breathing in mice

(2010) Till Manzke et al.   JOURNAL OF CLINICAL INVESTIGATION

Allosteric potentiation of glycine receptor chloride currents by glutamate

(2010) Jun Liu et al.   NATURE NEUROSCIENCE

Lack of positive allosteric modulation of mutated α1S267I glycine receptors by cannabinoids

(2010) Nilufar Foadi et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

3D structure and allosteric modulation of the transmembrane domain of pentameric ligand-gated ion channels

(2010) John E. Baenziger et al.   NEUROPHARMACOLOGY

Early history of glycine receptor biology in mammalian spinal cord circuits

(2010) Robert J. Callister   Frontiers in Molecular Neuroscience

Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential

(2009) Laetitia Mony et al.   BRITISH JOURNAL OF PHARMACOLOGY

Differential localization of γ-aminobutyric acid type a and glycine receptor subunits and gephyrin in the human pons, medulla oblongata and uppermost cervical segment of the spinal cord: An immunohistochemical study

(2009) H.J. Waldvogel et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Different binding modes of tropeines mediating inhibition and potentiation of α1 glycine receptors

(2009) Gábor Maksay et al.   JOURNAL OF NEUROCHEMISTRY

T-Type Calcium Channel Inhibition Underlies the Analgesic Effects of the Endogenous Lipoamino Acids

(2009) G. Barbara et al.   JOURNAL OF NEUROSCIENCE

Kinetic analysis of voltage-dependent potentiation and block of the glycine α3 receptor by a neuroactive steroid analogue

(2009) Xiaochun Jin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Different Forms of Glycine- and GABAA-Receptor Mediated Inhibitory Synaptic Transmission in Mouse Superficial and Deep Dorsal Horn Neurons

(2009) Wayne B Anderson et al.   Molecular Pain

Zinc in the physiology and pathology of the CNS

(2009) Stefano L. Sensi et al.   NATURE REVIEWS NEUROSCIENCE

The Nonpsychotropic Cannabinoid Cannabidiol Modulates and Directly Activates Alpha-1 and Alpha-1-Beta Glycine Receptor Function

(2009) Jörg Ahrens et al.   PHARMACOLOGY

Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine

(2008) Zhe Yang et al.   BIOCHEMICAL PHARMACOLOGY

Roles for Loop 2 Residues of α1 Glycine Receptors in Agonist Activation

(2008) Daniel K. Crawford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy

(2008) Sabrina A. Eichler et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Targets for ethanol action and antagonism in Loop 2 of the extracellular domain of glycine receptors

(2008) Daya I. Perkins et al.   JOURNAL OF NEUROCHEMISTRY

N-Arachidonoyl l-Serine, a Putative Endocannabinoid, Alters the Activation of N-Type Ca2+ Channels in Sympathetic Neurons

(2008) Juan Guo et al.   JOURNAL OF NEUROPHYSIOLOGY

General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal

(2008) Nicholas P. Franks   NATURE REVIEWS NEUROSCIENCE

Positive allosteric modulatory effects of ajulemic acid at strychnine-sensitive glycine α1- and α1β-receptors

(2008) Jörg Ahrens et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Identification of P2X4 receptor transmembrane residues contributing to channel gating and interaction with ivermectin

(2008) Irena Jelínkova et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The Anaesthetic Steroid Alphaxalone Positively Modulates α1-Glycine Receptor Function

(2008) Jörg Ahrens et al.   PHARMACOLOGY

A selective G  -linked intracellular mechanism for modulation of a ligand-gated ion channel by ethanol

(2008) G. E. Yevenes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ethanol's Molecular Targets

(2008) R. A. Harris et al.   Science Signaling