TRAIL: not just for tumors anymore?

Inflammation in Pulmonary Arterial Hypertension

(2012) Laura C. Price et al.   CHEST

TNF-related apoptosis-inducing ligand (TRAIL) exerts therapeutic efficacy for the treatment of pneumococcal pneumonia in mice

(2012) Kathrin Steinwede et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inhibition of tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) reverses experimental pulmonary hypertension

(2012) Abdul G. Hameed et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD8+ T Cells Use TRAIL To Restrict West Nile Virus Pathogenesis by Controlling Infection in Neurons

(2012) B. Shrestha et al.   JOURNAL OF VIROLOGY

Paigen Diet–Fed Apolipoprotein E Knockout Mice Develop Severe Pulmonary Hypertension in an Interleukin-1–Dependent Manner

(2011) Allan Lawrie et al.   AMERICAN JOURNAL OF PATHOLOGY

The Magnitude of the T Cell Response to a Clinically Significant Dose of Influenza Virus Is Regulated by TRAIL

(2011) E. L. Brincks et al.   JOURNAL OF IMMUNOLOGY

TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation

(2011) Emmet E. McGrath et al.   JOURNAL OF LEUKOCYTE BIOLOGY

RIPK-Dependent Necrosis and Its Regulation by Caspases: A Mystery in Five Acts

(2011) Douglas R. Green et al.   MOLECULAR CELL

HIV Infection Enhances TRAIL-Induced Cell Death in Macrophage by Down-Regulating Decoy Receptor Expression and Generation of Reactive Oxygen Species

(2011) Dan-Ming Zhu et al.   PLoS One

Therapeutic Targeting of CD95 and the TRAIL Death Receptors

(2011) Jeannette Gerspach et al.   Recent Patents on Anti-Cancer Drug Discovery

Regulating TRAIL Receptor-Induced Cell Death at the Membrane: A Deadly Discussion

(2011) Sarah Shirley et al.   Recent Patents on Anti-Cancer Drug Discovery

HIV/SIV Infection Primes Monocytes and Dendritic Cells for Apoptosis

(2011) Mireille Laforge et al.   PLoS Pathogens

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-1 and receptor-2 agonists for cancer therapy

(2009) Norma Lynn Fox et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

TRAIL Stimulates Proliferation of Vascular Smooth Muscle Cells via Activation of NF-κB and Induction of Insulin-like Growth Factor-1 Receptor

(2008) Mary M. Kavurma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lung epithelial apoptosis in influenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligand

(2008) Susanne Herold et al.   JOURNAL OF EXPERIMENTAL MEDICINE