Inhibition of tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) reverses experimental pulmonary hypertension

Paigen Diet–Fed Apolipoprotein E Knockout Mice Develop Severe Pulmonary Hypertension in an Interleukin-1–Dependent Manner

(2011) Allan Lawrie et al.   AMERICAN JOURNAL OF PATHOLOGY

Egr-1 Expression During Neointimal Development in Flow-Associated Pulmonary Hypertension

(2011) Michael G. Dickinson et al.   AMERICAN JOURNAL OF PATHOLOGY

TRAIL attenuates the development of atherosclerosis in apolipoprotein E deficient mice

(2011) Victoria Watt et al.   ATHEROSCLEROSIS

Bisoprolol Delays Progression Towards Right Heart Failure in Experimental Pulmonary Hypertension

(2011) Frances S. de Man et al.   Circulation-Heart Failure

Pigment Epithelium-derived Factor (PEDF) Promotes Tumor Cell Death by Inducing Macrophage Membrane Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)

(2011) Tsung-Chuan Ho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease

(2011) Wanli Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation

(2011) Emmet E. McGrath et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Novel transcript variants of TRAIL show different activities in activation of NF-κB and apoptosis

(2011) Pingzhang Wang et al.   LIFE SCIENCES

TRAIL promotes caspase-dependent pro-inflammatory responses via PKCδ activation by vascular smooth muscle cells

(2011) S Song et al.   Cell Death & Disease

Imatinib in Pulmonary Arterial Hypertension Patients with Inadequate Response to Established Therapy

(2010) Hossein A. Ghofrani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Autocrine Fibroblast Growth Factor-2 Signaling Contributes to Altered Endothelial Phenotype in Pulmonary Hypertension

(2010) Ly Tu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

TRAIL Promotes VSMC Proliferation and Neointima Formation in a FGF-2–, Sp1 Phosphorylation–, and NFκB-Dependent Manner

(2010) Jeffrey Chan et al.   CIRCULATION RESEARCH

Advanced Glycation End Product (AGE)-Receptor for AGE (RAGE) Signaling and Up-regulation of Egr-1 in Hypoxic Macrophages

(2010) Yunlu Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combined treatment with TRAIL and PPARγ ligands overcomes chemoresistance of ovarian cancer cell lines

(2010) Karen Bräutigam et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Dual Effects of TRAIL in Suppression of Autoimmunity: The Inhibition of Th1 Cells and the Promotion of Regulatory T Cells

(2010) T. Ikeda et al.   JOURNAL OF IMMUNOLOGY

Tie2-mediated loss of peroxisome proliferator-activated receptor-γ in mice causes PDGF receptor-β-dependent pulmonary arterial muscularization

(2009) C. Guignabert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Rosiglitazone Attenuates Chronic Hypoxia–Induced Pulmonary Hypertension in a Mouse Model

(2009) Rachel E. Nisbet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

TRAIL as a target in anti-cancer therapy

(2009) Gen Sheng Wu   CANCER LETTERS

TRAIL receptor mediates inflammatory cytokine release in an NF-κB-dependent manner

(2009) Wanhu Tang et al.   CELL RESEARCH

TRAIL/Apo2L Mediates the Release of Procoagulant Endothelial Microparticles Induced by Thrombin In Vitro

(2009) Stéphanie Simoncini et al.   CIRCULATION RESEARCH

S100A4 and Bone Morphogenetic Protein-2 Codependently Induce Vascular Smooth Muscle Cell Migration via Phospho–Extracellular Signal-Regulated Kinase and Chloride Intracellular Channel 4

(2009) Edda Spiekerkoetter et al.   CIRCULATION RESEARCH

Following TRAIL’s path in the immune system

(2009) Christina Falschlehner et al.   IMMUNOLOGY

Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents

(2009) Mohamed Izikki et al.   JOURNAL OF CLINICAL INVESTIGATION

The 4th World Symposium on Pulmonary Hypertension

(2009) Marc Humbert et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Future Perspectives for the Treatment of Pulmonary Arterial Hypertension

(2009) Hossein A. Ghofrani et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cellular and Molecular Basis of Pulmonary Arterial Hypertension

(2009) Nicholas W. Morrell et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Platelet-derived Growth Factor Expression and Function in Idiopathic Pulmonary Arterial Hypertension

(2008) Frédéric Perros et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Update in Pulmonary Arterial Hypertension 2007

(2008) Marc Humbert   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Standardized quantification of pulmonary fibrosis in histological samples

(2008) Ralf-Harto Hübner et al.   BIOTECHNIQUES

Interleukin-6 Overexpression Induces Pulmonary Hypertension

(2008) M. Kathryn Steiner et al.   CIRCULATION RESEARCH

OPG Is Regulated by  -Catenin and Mediates Resistance to TRAIL-Induced Apoptosis in Colon Cancer

(2008) E. N. De Toni et al.   CLINICAL CANCER RESEARCH

Right heart function and haemodynamics in pulmonary hypertension

(2008) A. R. Hemnes et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

TRAIL Stimulates Proliferation of Vascular Smooth Muscle Cells via Activation of NF-κB and Induction of Insulin-like Growth Factor-1 Receptor

(2008) Mary M. Kavurma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An antiproliferative BMP-2/PPARγ/apoE axis in human and murine SMCs and its role in pulmonary hypertension

(2008) Georg Hansmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Promotes Migration of Human Bone Marrow Multipotent Stromal Cells

(2008) Paola Secchiero et al.   STEM CELLS

Evidence of a Role for Osteoprotegerin in the Pathogenesis of Pulmonary Arterial Hypertension

(2007) Allan Lawrie et al.   AMERICAN JOURNAL OF PATHOLOGY