Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth

The Oncoprotein HBXIP Modulates the Feedback Loop of MDM2/p53 to Enhance the Growth of Breast Cancer

(2015) Hang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The alteration of Hippo/YAP signaling in the development of hypertrophic cardiomyopathy

(2014) Pei Wang et al.   BASIC RESEARCH IN CARDIOLOGY

HDAC6 sustains growth stimulation by prolonging the activation of EGF receptor through the inhibition of rabaptin-5-mediated early endosome fusion in gastric cancer

(2014) Se Jin Park et al.   CANCER LETTERS

The oncoprotein HBXIP enhances angiogenesis and growth of breast cancer through modulating FGF8 and VEGF

(2014) Fabao Liu et al.   CARCINOGENESIS

Overexpression of MYC and EZH2 cooperates to epigenetically silence MST1 expression

(2014) Gamze Kuser-Abali et al.   Epigenetics

Co-Activation of Nuclear Factor-κB and Myocardin/Serum Response Factor Conveys the Hypertrophy Signal of High Insulin Levels in Cardiac Myoblasts

(2014) Rosalinda Madonna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiomotin decreases lung cancer progression by sequestering oncogenic YAP/TAZ and decreasing Cyr61 expression

(2014) Y-L Hsu et al.   ONCOGENE

The Biology of YAP/TAZ: Hippo Signaling and Beyond

(2014) Stefano Piccolo et al.   PHYSIOLOGICAL REVIEWS

Proteomic identification and functional characterization of MYH9, Hsc70, and DNAJA1 as novel substrates of HDAC6 deacetylase activity

(2014) Linlin Zhang et al.   Protein & Cell

microRNA-138 plays a role in hypoxic pulmonary vascular remodelling by targeting Mst1

(2013) Shanshan Li et al.   BIOCHEMICAL JOURNAL

Lysine-5 Acetylation Negatively Regulates Lactate Dehydrogenase A and Is Decreased in Pancreatic Cancer

(2013) Di Zhao et al.   CANCER CELL

The oncoprotein HBXIP activates transcriptional coregulatory protein LMO4 via Sp1 to promote proliferation of breast cancer cells

(2013) Lin Yue et al.   CARCINOGENESIS

HDAC6 promotes hepatocellular carcinoma progression by inhibiting P53 transcriptional activity

(2013) Gang Ding et al.   FEBS LETTERS

The oncoprotein HBXIP upregulates Lin28Bviaactivating TF II D to promote proliferation of breast cancer cells

(2013) Qian Liu et al.   INTERNATIONAL JOURNAL OF CANCER

The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics

(2013) R Kang et al.   ONCOGENE

Prognostic significance of mammalian sterile 20-like kinase 1 in breast cancer

(2013) Xiaoyan Lin et al.   TUMOR BIOLOGY

MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1

(2013) Ching-Wen Lin et al.   Nature Communications

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

(2012) Fa-Xing Yu et al.   CELL

Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1

(2012) Liron Bar-Peled et al.   CELL

The Oncoprotein HBXIP Uses Two Pathways to Up-regulate S100A4 in Promotion of Growth and Migration of Breast Cancer Cells

(2012) Shuangping Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors

(2012) Marco Montagner et al.   NATURE

The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway

(2012) Wanjin Hong et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Negative Regulation of the Hippo Pathway by E3 Ubiquitin Ligase ITCH Is Sufficient to Promote Tumorigenicity

(2011) Z. Salah et al.   CANCER RESEARCH

MST1 Is a Multifunctional Caspase-Independent Inhibitor of Androgenic Signaling

(2011) B. Cinar et al.   CANCER RESEARCH

miR-520b Regulates Migration of Breast Cancer Cells by Targeting Hepatitis B X-interacting Protein and Interleukin-8

(2011) Nan Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deregulation of Hippo kinase signalling in Human hepatic malignancies

(2011) Hua Li et al.   LIVER INTERNATIONAL

Acetylation Regulates Gluconeogenesis by Promoting PEPCK1 Degradation via Recruiting the UBR5 Ubiquitin Ligase

(2011) Wenqing Jiang et al.   MOLECULAR CELL

Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth

(2011) Lei Lv et al.   MOLECULAR CELL

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

(2010) B. Zhao et al.   GENES & DEVELOPMENT

The Role of HDAC6 in Cancer

(2010) Grace I. Aldana-Masangkay et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Acetylation of WRN Protein Regulates Its Stability by Inhibiting Ubiquitination

(2010) Kai Li et al.   PLoS One

Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation

(2009) Hyunkyung Jeong et al.   CELL

Down-regulation of Mammalian Sterile 20-Like Kinase 1 by Heat Shock Protein 70 Mediates Cisplatin Resistance in Prostate Cancer Cells

(2008) A. Ren et al.   CANCER RESEARCH

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

PCAF Acetylates β-Catenin and Improves Its Stability

(2008) Xinjian Ge et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE