An antibody to amphiregulin, an abundant growth factor in patients’ fluids, inhibits ovarian tumors

Amphiregulin

(2014) Carmen Berasain et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

New developments in the treatment of ovarian cancer--future perspectives

(2013) J. Lopez et al.   ANNALS OF ONCOLOGY

Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer

(2013) N Panupinthu et al.   ONCOGENE

The epidermal growth factor receptor as a therapeutic target in epithelial ovarian cancer

(2012) Ting Gui et al.   Cancer Epidemiology

EGFR ligands exhibit functional differences in models of paracrine and autocrine signaling

(2012) Kristy J. Wilson et al.   GROWTH FACTORS

Epidermal growth factor receptor and HER-3 restrict cell response to sorafenib in hepatocellular carcinoma cells

(2012) Marie-José Blivet-Van Eggelpoël et al.   JOURNAL OF HEPATOLOGY

A Potent Anti-HB-EGF Monoclonal Antibody Inhibits Cancer Cell Proliferation and Multiple Angiogenic Activities of HB-EGF

(2012) Shuji Sato et al.   PLoS One

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Amphiregulin Exosomes Increase Cancer Cell Invasion

(2011) James N. Higginbotham et al.   CURRENT BIOLOGY

Erlotinib or gefitinib for the treatment of relapsed platinum pretreated non-small cell lung cancer and ovarian cancer: A systematic review

(2011) Mark Murphy et al.   DRUG RESISTANCE UPDATES

Treatment of HER2-positive breast cancer: current status and future perspectives

(2011) Carlos L. Arteaga et al.   Nature Reviews Clinical Oncology

A recombinant decoy comprising EGFR and ErbB-4 inhibits tumor growth and metastasis

(2011) M Lindzen et al.   ONCOGENE

A Neutralizing RNA Aptamer against EGFR Causes Selective Apoptotic Cell Death

(2011) Carla Lucia Esposito et al.   PLoS One

An Activated ErbB3/NRG1 Autocrine Loop Supports In Vivo Proliferation in Ovarian Cancer Cells

(2010) Qing Sheng et al.   CANCER CELL

Sym004: A Novel Synergistic Anti-Epidermal Growth Factor Receptor Antibody Mixture with Superior Anticancer Efficacy

(2010) M. W. Pedersen et al.   CANCER RESEARCH

A two-tiered mechanism of EGFR inhibition by RALT/MIG6 via kinase suppression and receptor degradation

(2010) Yuri Frosi et al.   JOURNAL OF CELL BIOLOGY

Toll-like receptor 4 differentially regulates epidermal growth factor-related growth factors in response to intestinal mucosal injury

(2010) David Hsu et al.   LABORATORY INVESTIGATION

Mutant p53 initiates a feedback loop that involves Egr-1/EGF receptor/ERK in prostate cancer cells

(2010) L Sauer et al.   ONCOGENE

Roles for Growth Factors in Cancer Progression

(2010) Esther Witsch et al.   PHYSIOLOGY

Tailored cancer immunotherapy using combinations of chemotherapy and a mixture of antibodies against EGF-receptor ligands

(2010) Moshit Lindzen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Role of c-Cbl in Amphiregulin-Induced Recycling and Signaling of the Endogenous Epidermal Growth Factor Receptor†

(2009) Aleksander Baldys et al.   BIOCHEMISTRY

ErbB receptors and signaling pathways in cancer

(2009) Nancy E Hynes et al.   CURRENT OPINION IN CELL BIOLOGY

Epidermal Growth Factor Receptor Expression in Serous Ovarian Carcinoma: An Immunohistochemical Study With Galectin-3 and Cyclin D1 and Outcome

(2009) Hermann Brustmann   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Differential Effects of EGFR Ligands on Endocytic Sorting of the Receptor

(2009) Kirstine Roepstorff et al.   TRAFFIC

Targeting the Epidermal Growth Factor Receptor in Epithelial Ovarian Cancer: Current Knowledge and Future Challenges

(2009) Doris R. Siwak et al.   Journal of Oncology

EGF and amphiregulin differentially regulate Cbl recruitment to endosomes and EGF receptor fate

(2008) Kathryn A. Stern et al.   BIOCHEMICAL JOURNAL

Dual-specificity MAP kinase phosphatases (MKPs) and cancer

(2008) Stephen M. Keyse   CANCER AND METASTASIS REVIEWS

Autocrine Production of Amphiregulin Predicts Sensitivity to Both Gefitinib and Cetuximab in EGFR Wild-type Cancers

(2008) K. Yonesaka et al.   CLINICAL CANCER RESEARCH

Quantitative modeling perspectives on the ErbB system of cell regulatory processes

(2008) Matthew J. Lazzara et al.   EXPERIMENTAL CELL RESEARCH

EGFR family: Structure physiology signalling and therapeutic targets†

(2008) Antony W. Burgess   GROWTH FACTORS

Systems Biology of Growth Factor-Induced Receptor Endocytosis

(2008) Yaara Zwang et al.   TRAFFIC