Hepatitis B virus X protein induces EpCAM expression via active DNA demethylation directed by RelA in complex with EZH2 and TET2

Reprogramming the Methylome: Erasing Memory and Creating Diversity

(2014) Heather J. Lee et al.   Cell Stem Cell

Hepatocyte nuclear factor 4α-nuclear factor-κB feedback circuit modulates liver cancer progression

(2014) Bei-Fang Ning et al.   HEPATOLOGY

EpCAM: Structure and function in health and disease

(2013) Ulrike Schnell et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells

(2013) Eunhee Kim et al.   CANCER CELL

Dnmt3L Antagonizes DNA Methylation at Bivalent Promoters and Favors DNA Methylation at Gene Bodies in ESCs

(2013) Francesco Neri et al.   CELL

The transcription factor SALL4 regulates stemness of EpCAM-positive hepatocellular carcinoma

(2013) Sha Sha Zeng et al.   JOURNAL OF HEPATOLOGY

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX

(2013) Myunggon Ko et al.   NATURE

Regulated Intramembrane Proteolysis and Degradation of Murine Epithelial Cell Adhesion Molecule mEpCAM

(2013) Matthias Hachmeister et al.   PLoS One

Role of lysine methylation of NF- B in differential gene regulation

(2013) T. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic Regulation of SOX9 by the NF-κB Signaling Pathway in Pancreatic Cancer Stem Cells

(2013) Lei Sun et al.   STEM CELLS

PPARγ-induced PARylation promotes local DNA demethylation by production of 5-hydroxymethylcytosine

(2013) Katsunori Fujiki et al.   Nature Communications

PU.1 target genes undergo Tet2-coupled demethylation and DNMT3b-mediated methylation in monocyte-to-osteoclast differentiation

(2013) Lorenzo de la Rica et al.   GENOME BIOLOGY

Subset of Suz12/PRC2 target genes is activated during hepatitis B virus replication and liver carcinogenesis associated with HBV X protein

(2012) Leo L. Studach et al.   HEPATOLOGY

EpCAM regulates cell cycle progression via control of cyclin D1 expression

(2012) A Chaves-Pérez et al.   ONCOGENE

The Transcriptional Specificity of NF-κB Dimers Is Coded within the κB DNA Response Elements

(2012) Vivien Ya-Fan Wang et al.   Cell Reports

Transcription factors and molecular epigenetic marks underlying EpCAM overexpression in ovarian cancer

(2011) B T F van der Gun et al.   BRITISH JOURNAL OF CANCER

The role of EZH2 in tumour progression

(2011) C-J Chang et al.   BRITISH JOURNAL OF CANCER

Guiding DNA Methylation

(2011) Alexander Meissner   Cell Stem Cell

Regulation of mammalian DNA methyltransferases: a route to new mechanisms

(2011) Hélène Denis et al.   EMBO REPORTS

Proteins ZNF198 and SUZ12 are down-regulated in hepatitis B virus (HBV) X protein-mediated hepatocyte transformation and in HBV replication

(2011) Wen-Horng Wang et al.   HEPATOLOGY

Context-Specific Regulation of NF-κB Target Gene Expression by EZH2 in Breast Cancers

(2011) Shuet Theng Lee et al.   MOLECULAR CELL

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

Polo-like Kinase 1 Activated by the Hepatitis B Virus X Protein Attenuates Both the DNA Damage Checkpoint and DNA Repair Resulting in Partial Polyploidy

(2010) Leo Studach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

The Emerging Role of EpCAM in Cancer and Stem Cell Signaling

(2009) M. Munz et al.   CANCER RESEARCH

Polo-like kinase 1 inhibition suppresses hepatitis B virus X protein-induced transformation in an in vitro model of liver cancer progression

(2009) Leo L. Studach et al.   HEPATOLOGY

Mouse hepatoblasts at distinct developmental stages are characterized by expression of EpCAM and DLK1: Drastic change of EpCAM expression during liver development

(2009) Minoru Tanaka et al.   MECHANISMS OF DEVELOPMENT

Nuclear signalling by tumour-associated antigen EpCAM

(2009) Dorothea Maetzel et al.   NATURE CELL BIOLOGY

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

(2008) Taro Yamashita et al.   GASTROENTEROLOGY

Is NF-κB a good target for cancer therapy? Hopes and pitfalls

(2008) Véronique Baud et al.   NATURE REVIEWS DRUG DISCOVERY

ZNF198 Stabilizes the LSD1–CoREST–HDAC1 Complex on Chromatin through Its MYM-Type Zinc Fingers

(2008) Christian B. Gocke et al.   PLoS One