HSP90AA1-mediated autophagy promotes drug resistance in osteosarcoma

Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling

(2016) Caixia Guo et al.   International Journal of Nanomedicine

Small Heat Shock Protein Beta-1 (HSPB1) Is Upregulated and Regulates Autophagy and Apoptosis of Renal Tubular Cells in Acute Kidney Injury

(2015) Tatsuki Matsumoto et al.   PLoS One

Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells

(2014) MASAKI MORI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Evolution of acquired resistance to anti-cancer therapy

(2014) Jasmine Foo et al.   JOURNAL OF THEORETICAL BIOLOGY

Resveratrol Triggers Protective Autophagy Through the Ceramide/Akt/mTOR Pathway in Melanoma B16 Cells

(2014) Meng Wang et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Natural Products Targeting Autophagy via the PI3K/Akt/mTOR Pathway as Anticancer Agents

(2013) Hui Sun et al.   Anti-Cancer Agents in Medicinal Chemistry

Targeting HMGB1-mediated autophagy as a novel therapeutic strategy for osteosarcoma

(2012) Jun Huang et al.   Autophagy

Regulation of survival and chemoresistance by HSP90AA1 in ovarian cancer SKOV3 cells

(2012) Shu-hua Chu et al.   MOLECULAR BIOLOGY REPORTS

Losses of Chromosome 5q and 14q Are Associated with Favorable Clinical Outcome of Patients with Gastric Cancer

(2012) T. E. Buffart et al.   ONCOLOGIST

Nrf2 expression is associated with poor outcome in osteosarcoma

(2012) Jae-Young Park et al.   PATHOLOGY

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics

(2011) Tracey R. O’Donovan et al.   Autophagy

Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein

(2011) Zhuo Wang et al.   Autophagy

Synergistic inhibitory effect of apomine and lovastatin on osteosarcoma cell growth

(2011) Gatien Moriceau et al.   CANCER

Decreased heat shock protein 27 expression and altered autophagy in human cells harboring A8344G mitochondrial DNA mutation

(2011) Chin-Yi Chen et al.   MITOCHONDRION

Autophagy as a target for anticancer therapy

(2011) Filip Janku et al.   Nature Reviews Clinical Oncology

Association and dissociation of autophagy, apoptosis and necrosis by systematic chemical study

(2011) S Shen et al.   ONCOGENE

ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy

(2010) Liang Qin et al.   Autophagy

Osteosarcoma is characterised by reduced expression of markers of osteoclastogenesis and antigen presentation compared with normal bone

(2010) L Endo-Munoz et al.   BRITISH JOURNAL OF CANCER

Selective Autophagy in Cancer Development and Therapy

(2010) Ivan Dikic et al.   CANCER RESEARCH

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Implication of Heat Shock Protein 90 (HSP90) in Tumor Angiogenesis: A Molecular Target for Anti-Angiogenic Therapy?

(2010) K. Staufer et al.   CURRENT CANCER DRUG TARGETS

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Cellular responses to endoplasmic reticulum stress and apoptosis

(2009) Vanya I. Rasheva et al.   APOPTOSIS

The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival

(2009) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Guidelines for the nomenclature of the human heat shock proteins

(2008) Harm H. Kampinga et al.   CELL STRESS & CHAPERONES

Heat Shock Protein 90 as a Drug Target: Some Like It Hot

(2008) U. Banerji   CLINICAL CANCER RESEARCH

Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer

(2008) Qingshan Chang et al.   JOURNAL OF HEPATOLOGY

Integration of Gene Dosage and Gene Expression in Non-Small Cell Lung Cancer, Identification of HSP90 as Potential Target

(2008) Mariëlle I. Gallegos Ruiz et al.   PLoS One