SPOP suppresses tumorigenesis by regulating Hedgehog/Gli2 signaling pathway in gastric cancer

L1 and epithelial cell adhesion molecules associated with gastric cancer progression and prognosis in examination of specimens from 601 patients

(2013) Yuan-Yu Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover

(2013) C. Geng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Hedgehog signaling pathway as a therapeutic target in various types of cancer

(2011) Hideya Onishi et al.   CANCER SCIENCE

Activation of the hedgehog pathway in chronic myelogeneous leukemia patients

(2011) Bing Long et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Hedgehog signalling in gut development, physiology and cancer

(2011) Juanita L. Merchant   JOURNAL OF PHYSIOLOGY-LONDON

Elevated expression of CUEDC2 protein confers endocrine resistance in breast cancer

(2011) Xin Pan et al.   NATURE MEDICINE

Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1

(2011) C Li et al.   ONCOGENE

Expression and regulation mechanisms of Sonic Hedgehog in breast cancer

(2010) Wei Cui et al.   CANCER SCIENCE

The Role of the Hedgehog Signaling Pathway in the Development of Basal Cell Carcinoma and Opportunities for Treatment

(2010) I. Caro et al.   CLINICAL CANCER RESEARCH

Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors

(2010) C. Wang et al.   DEVELOPMENT

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases

(2009) Min Zhuang et al.   MOLECULAR CELL

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Hedgehog Signaling in Development and Cancer

(2008) Jin Jiang et al.   DEVELOPMENTAL CELL

Coordinated Activation of the Nuclear Ubiquitin Ligase Cul3-SPOP by the Generation of Phosphatidylinositol 5-Phosphate

(2008) Matthew W. Bunce et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HSP90β Regulates Rapsyn Turnover and Subsequent AChR Cluster Formation and Maintenance

(2008) Shiwen Luo et al.   NEURON

Stromal control of oncogenic traits expressed in response to the overexpression of GLI2, a pleiotropic oncogene

(2008) A M Snijders et al.   ONCOGENE