Article
Multidisciplinary Sciences
Sardar Muhammad Rafique Khan, Tanveer Akhter, Mumtaz Hussain
Summary: The study conducted in the Upper Neelum Valley of Azad Jammu & Kashmir, Pakistan, documented 39 plant species used by indigenous communities to cure 21 different diseases in 7 types of livestock, with the highest number of plants belonging to the Polygonaceae family. Roots were the most commonly used part for preparing ethnoveterinary medicines, and Saussurea lappa was the most frequently cited and had the highest use value.
Article
Plant Sciences
Olfa Karous, Imtinen Ben Haj Jilani, Zeineb Ghrabi-Gammar
Summary: The region of Ouled Dabbeb in Southern Tunisia serves as a rich source of plant biodiversity and ethnobotanical knowledge, with the local community utilizing various plant species for therapeutic, food, domestic, ethnoveterinary, cosmetic, and ritual purposes. The study revealed a transmission of knowledge between current population and semi-nomadic forefathers, with a significant portion of cited taxa stemming from the semi-nomadic lifestyle of ancestors. This data could be valuable for further phytochemical and pharmacological research, as well as the conservation of endangered plant species.
Article
Multidisciplinary Sciences
Mubashrah Munir, Sehrish Sadia, Adnan Khan, Bakht Zareen Rahim, Brian Gagosh Nayyar, Khawaja Shafique Ahmad, Arshad Mahmood Khan, Ishrat Fatima, Rahmatullah Qureshi
Summary: This study collected ethnobotanical data on plant resources in rural areas of Pakistan, revealing unique traditional knowledge among native people. The research findings suggest that traditional knowledge of medicinal plants is declining due to the popularity of allopathic medicine, highlighting the importance of conservation and documentation of this valuable heritage.
Article
Plant Sciences
Riccardo Motti, Marco Marotta, Giuliano Bonanomi, Stefania Cozzolino, Anna Di Palma
Summary: This study analyzes the traditional uses of wild plants in the Ansanto Valley area in southern Italy, contributing to the ethnobotanical knowledge of the region. A total of 117 plant species were documented for traditional use, with 544 reports related to medicinal plants. New use reports for medicinal and veterinary applications were discovered, including the first mention of Sedum cepaea as a medicinal plant in Italy and the Mediterranean region.
Article
Plant Sciences
Ivana Vitasovic-Kosic, Antonija Hodak, Lukasz Luczaj, Mara Mari, Josip Juracak
Summary: This study analyzed the use of plants and fungi in three municipalities of Lika-Senj County. The results showed differences in ethnobotanical and ecological knowledge between the three areas. The usage of wild plants is still prevalent in Perugk, while Lovinac has fewer plant species used. The study also found medicinal and edible uses of certain plants.
Article
Agriculture, Dairy & Animal Science
Raees Khan, Anely Nedelcheva, Sheikh Zain Ul Abidin, Muhammad Zeeshan Bhatti, Shujaul Mulk Khan, Asad Ullah, Rida Fatima Saeed, Abida Aziz, Hadia Gul, Yunus Dogan
Summary: This study explored the plant species used by local communities in Malakand Agency, Pakistan for foraging and ethnoveterinary purposes. A total of 91 forage species from 26 families were documented, along with their ethnoveterinary applications. Local communities commonly use a diverse range of forage species in conjunction with indigenous knowledge of ethnoveterinary uses. These forage species have the potential to overcome the recent fodder shortage.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2023)
Article
Multidisciplinary Sciences
Muhammad Sajjad Iqbal, Khawaja Shafique Ahmad, Muhammad Azhar Ali, Muhammad Akbar, Ansar Mehmood, Fahim Nawaz, Syed Atiq Hussain, Noshia Arshad, Saba Munir, Hamna Arshad, Khizra Shahbaz, Rainer W. Bussmann
Summary: The study in the non-recognized wetland of Head Maralla in Pakistan identified 119 plant species utilized for therapeutic purposes, showcasing a high consensus among informants about the use of these plants for treating specific ailments. The ethnobotanical data revealed a diverse range of plant species with potential medical benefits, highlighting the importance of conservation efforts for preserving ethnoecological knowledge.
Article
Plant Sciences
Adnan Ali Shah, Lal Badshah, Noor Khalid, Muhammad Ali Shah, Ajmal Khan Manduzai, Abdullah Faiz, Matteo De Chiara, Giulia Mattalia, Renata Soukand, Andrea Pieroni
Summary: The study of migrants' ethnobotany can help to address the socio-ecological factors affecting changes in local ecological knowledge. Through conversations with local Pathans and Afghan refugees in NW Pakistan, 145 wild plant and mushroom folk taxa were recorded. The findings suggest that there are significant differences in plant knowledge between Afghan refugees and local Pathans, which may be influenced by stricter border policies and economic conditions.
Article
Plant Sciences
Olawale Olusegun Onifade, Gabriel Olulakin Adesina, Samuel Adelani Babarinde
Summary: Snakebite is a significant threat to arable farmers, cattle herdsmen, and agricultural workers worldwide. This study focused on identifying and evaluating the chemical composition of plant species used for snakebite management by cattle herdsmen in southwest Nigeria. Through purposeful sampling, 100 herdsmen were surveyed to identify commonly used plant species and their preparation methods.
SOUTH AFRICAN JOURNAL OF BOTANY
(2022)
Article
Veterinary Sciences
Sabith Rehman, Zafar Iqbal, Rahmatullah Qureshi, Inayat Ur Rahman, Shazia Sakhi, Imran Khan, Abeer Hashem, Al-Bandari Fahad Al-Arjani, Khalid F. Almutairi, Elsayed Fathi Abd Allah, Niaz Ali, Muhammad Azhar Khan, Farhana Ijaz
Summary: Domestic animals play a vital role in human civilization. The tribes of North Waziristan have extensive knowledge of ethnoveterinary medicines and use local plants to treat animal diseases.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Plant Sciences
Muhammad Usman, Allah Ditta, Faridah Hanum Ibrahim, Ghulam Murtaza, Muhammad Nawaz Rajpar, Sajid Mehmood, Mohd Nazre Bin Saleh, Muhammad Imtiaz, Seemab Akram, Waseem Razzaq Khan
Summary: Rural communities rely on herbal medicines due to lack of proper infrastructure and poor economic conditions; local inhabitants primarily use medicinal plants to treat various illnesses, including those from different plant families; the study area is rich in plants with ethnobotanical potential for treating a wide range of diseases, as indicated by various indices.
Article
Veterinary Sciences
Sheikh Zain Ul Abidin, Afifa Munem, Raees Khan, Gaber El-Saber Batiha, Mushtaq Amhad, Muhammad Zafar, Atif Ali Khan Khalil, Helal F. Hetta, Mohamed H. Mahmoud, Abdus Sami, Muhammad Zeeshan Bhatti
Summary: The study investigated ethnoveterinary medicinal practices in three different communities, revealing cross-cultural consensus in the use of medicinal plants across different ethnic groups. A total of 59 plant species were documented, with 14 medicinal plants commonly utilized by three different ethnic communities, indicating low interregional consensus.
VETERINARY MEDICINE AND SCIENCE
(2021)
Article
Parasitology
Muhammad Rizwan, Shahzad Ali, Arshad Javid, Muhammad Imran Rashid
Summary: This study investigated the prevalence of Toxoplasma gondii infection in rodents in the Sahiwal division of Pakistan, and found a higher infection rate in Rattus norvegicus compared to Rattus rattus. All risk factors were not statistically significant.
PARASITOLOGY RESEARCH
(2023)
Article
Biodiversity Conservation
Zeeshan Siddique, Nasir Shad, Ghulam Mujtaba Shah, Abid Naeem, Liu Yali, Muhammad Hasnain, Arshad Mahmood, Muhammad Sajid, Muhammad Idrees, Ilyas Khan
Summary: The study revealed that local residents in the Haripur District have great confidence in the use of ethnomedicinal plants and continue to use them for treating various ailments. Different plant parts are prepared using various methods, with decoction/tea being the most popular. Many species are utilized to treat digestive system-related problems in both humans and livestock.
JOURNAL OF ETHNOBIOLOGY AND ETHNOMEDICINE
(2021)
Letter
Geosciences, Multidisciplinary
Sajjad Hussain, Ali Raza, Hazem Ghassan Abdo, Muhammad Mubeen, Aqil Tariq, Wajid Nasim, Muhammad Majeed, Hussein Almohamad, Ahmed Abdullah Al Dughairi
Summary: This research studied the changes in land cover and the relation of different vegetation indices with temperature in Sahiwal region, Pakistan using multi-temporal satellite data. The results showed that about 2.43% of vegetation area has been converted to roads and built-up areas in the past 24 years. The study also identified the correlation between different vegetation indices and land surface temperature, and highlighted the potential of remote sensing technology in monitoring vegetation index changes over time.
GEOSCIENCE LETTERS
(2023)
Article
Medicine, General & Internal
John D. Scott, Muhammad S. Sajid, Emily L. Pascoe, Janet E. Foley
Summary: A one-day clinic in Ontario, Canada, identified B. odocoilei in two out of 19 participants through PCR testing and DNA sequencing. The DNA amplicons from these individuals closely matched the type strains of B. odocoilei in GenBank. Both patients exhibited hallmark symptoms of human babesiosis. This discovery provides evidence of B. odocoilei's pathogenicity to humans and the potential for serological cross-reactivity.
Article
Veterinary Sciences
H. M. Rizwan, M. S. Sajid, H. Abbas, M. N. Khan, Q. Akram, A. Shantim
Summary: The study evaluated the predominance and related risk factors of sheep fasciolosis in Faisalabad district, Punjab, Pakistan, showing a higher prevalence in female and adult animals. Spring and winter were the seasons with the highest infection rates.
JOURNAL OF THE HELLENIC VETERINARY MEDICAL SOCIETY
(2021)
Article
Veterinary Sciences
Shujaat Hussain, Muhammad Saqib, Hosny El-Adawy, Muhammad Hammad Hussain, Tariq Jamil, Muhammad Sohail Sajid, Mughees Aizaz Alvi, Muzafar Ghafoor, Muhammad Haleem Tayyab, Zaeem Abbas, Katja Mertens-Scholz, Heinrich Neubauer, Iahtasham Khan, Muhammad Khalid Mansoor, Ghulam Muhammad
Summary: This study aimed to investigate the prevalence and associated risk factors of coxiellosis in camel herds in Punjab Province, Pakistan. The results showed a high seroprevalence of coxiellosis in camels, with potential risk factors including desert area, summer season, tick infestation, and female sex. Additionally, the study found a presence of Coxiella burnetii DNA in ELISA-negative samples.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Public, Environmental & Occupational Health
Zaheer Abbas, Muhammad Kasib Khan, Rao Zahid Abbas, Zia Ud Din Sindhu, Muhammad Sohail Sajid, Amir Munir, Abdul Wahid, Arsalan Zafar, Muhammad Adnan Sabir Mughal, Muhammad Imran, Rashid Mehmood, Muhammad Nadeem
Summary: This study evaluated the prevalence of Cryptosporidium and Giardia parasites in different water bodies, soil, and vegetables in Pakistan. The results showed high prevalence of these parasites in sewage water, municipal water, and raw vegetables.
Article
Veterinary Sciences
Kashif Kamran, Ali Akbar, Mahrukh Naseem, Abdul Samad, Samiullah, Jahangir Khan Achakzai, Zia Ur Rehman, Muhammad Sohail Sajid, Abid Ali
Summary: This study investigates the current status of healthcare management and welfare of donkeys in resource-poor countries. The findings highlight common health issues in donkeys, such as hyperlipaemia, lameness, and dental problems, with a significant proportion of donkeys being underweight.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Veterinary Sciences
Mahvish Maqbool, Muhammad Sohail Sajid, Zafar Iqbal, Muhammad Saqib
Summary: The current study aimed to explore the correlation between different risk factors and the infestation rate of hard ticks in livestock population in Faisalabad district. The results showed that season, age, sex, feeding system, housing system, type of farming, farm structure, and hygienic measures were significantly associated with tick infestation rate. The study findings provide valuable information for tick control in similar husbandry systems in the selected areas and other regions.
JOURNAL OF THE HELLENIC VETERINARY MEDICAL SOCIETY
(2022)
Article
Microbiology
Hamidullah, Muhammad Saqib, Muhammad Sohail Sajid, Sabir Hussain, Hafiz Muhammad Rizwan, Khurram Ashfaq, Sadia Ghazanfer, Asif Ali Butt, Mahvish Maqbool, Sibtain Ahmad, Olivier Andre Sparagano
Summary: The study found a high prevalence of canine toxoplasmosis in the owned and stray dog populations in Faisalabad District, Punjab, Pakistan. Bulldogs and Bhakarwal dogs showed the highest prevalence among owned and stray dogs, respectively. Young and female dogs were more susceptible to toxoplasmosis.
Article
Microbiology
Mahvish Rajput, Muhammad Sohail Sajid, Muhammad Imran, Muhammad Tariq Javed, Olivier Andre Sparagano
Summary: Livestock owners in Pakistan have inadequate knowledge, attitude, and practices (KAP) regarding ticks and tick-borne diseases. There is a need for appropriate education and extension programs to enhance the adoption of effective tick prevention and control strategies.
Article
Agriculture, Multidisciplinary
Muhammad Abdullah Malik, Muhammad Sohail Sajid, Zafar Iqbal, Muhammad Saqib
Summary: This study investigates the association between climatic determinants and the abundance of Aedes (Ae.) aegypti larvae in indoor and outdoor environments. The results reveal a significant correlation between climatic factors and the prevalence of Ae. aegypti immatures in different breeding containers, regardless of the study districts and seasons. However, a non-significant association is observed between the prevalence of Ae. aegypti immatures in different breeding containers and summer season in district Faisalabad. The findings contribute to the understanding of Ae. aegypti's preferred breeding habitats and can inform the development of effective control strategies.
PAKISTAN JOURNAL OF AGRICULTURAL SCIENCES
(2023)
Article
Public, Environmental & Occupational Health
Haider Abbas, Hafiz Muhammad Rizwan, Muhammad Younus, Muhammad Sohail Sajid, Shahid Hussain Farooqi, Zeeshan Iqbal, Muhammad Imran, Usman Amanat, Nida Wazir, Muhammad Ahsan Naeem
Summary: This study describes the clinical manifestation of concurrent infection of blood-borne parasites and gastrointestinal nematodes in Pakistani dogs and highlights the importance of prompt veterinary intervention.
JOURNAL OF ARTHROPOD-BORNE DISEASES
(2022)
Article
Veterinary Sciences
M. S. Sajid, A. Iqbal, H. M. Rizwan, S. Naz, M. Maqbool, M. A. Malik, M. Jawad-ul-Hassan
Summary: The study investigated the prevalence, risk factors, and efficacy of cypermethrin against louse infestation in buffalo population. The results showed that cypermethrin was effective in treating louse infestation in buffalos.
JOURNAL OF THE HELLENIC VETERINARY MEDICAL SOCIETY
(2022)
Article
Agriculture, Multidisciplinary
F. A. Atif, M. A. Zaman, K. Hussain, M. F. Qamar, M. S. Sajid, U. Iqbal, S. Mehnaz
Summary: Anaplasmosis is a significant disease in cattle worldwide, including Pakistan. A study conducted in district Jhang revealed that tick infestation, large herd size, exotic cattle aged 2-4 years, 30-day interval between acaricidal application, and summer season are important risk factors associated with molecular occurrence of A. marginale infection in cattle. Further research is needed to investigate genetic diversity for better prevention and control of bovine anaplasmosis in the region.
JOURNAL OF ANIMAL AND PLANT SCIENCES-JAPS
(2021)
Review
Parasitology
Hafiz M. Rizwan, Muhammad S. Sajid, Asim Shamim, Haider Abbas, Abdul Qudoos, Mahvish MaqbooI, Muhammad A. Malik, Zubaria S. Amin
Summary: Sheep production is vital for resource-poor farmers, yet parasitic diseases pose a major obstacle to the development of commercial livestock business. The prevalence of parasitic infections in sheep is multifactorial and can lead to significant economic losses, impacting not only animal health but also milk, meat, and wool production.
PARASITOLOGISTS UNITED JOURNAL
(2021)
Article
Agriculture, Multidisciplinary
S. Ahmad, M. S. Sajid, R. Tabassum, R. M. Siddique, M. Imran, M. A. Malik
Summary: The study investigated the distribution of gastrointestinal parasites in sheep and goats in Faisalabad, Pakistan. Various intrinsic determinants and husbandry practices were found to be significantly associated with parasite prevalence. Ivermectin showed higher efficacy compared to levamisole, indicating it as a better choice for parasitic management in the area.
JOURNAL OF ANIMAL AND PLANT SCIENCES-JAPS
(2021)
Article
Parasitology
Syed Nadeem Badar, Zafar Iqbal, Muhammad Sohail Sajid, Hafiz Muhammad Rizwan, Muhammad Shareef, Muhammad Abdullah Malik, Muhammad Nisar Khan
Summary: The present study evaluated the anthelmintic activities of Arundo donax, Areca catechu, and Ferula assa-foetida. The results indicated that the extract of Ferula assa-foetida was the most effective among the three plants tested.
REVISTA BRASILEIRA DE PARASITOLOGIA VETERINARIA
(2021)
Correction
Plant Sciences
Lingmiao Wen, Tinglan Zhang, Fangfang Chen, Lin Hu, Chongyang Dou, Xian Ding, Alvin Altamirano, Guihua Wei, Zhiyong Yan
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Qing Tang, Mengfei Xu, Shunqin Long, Yaya Yu, Changju Ma, Rui Wang, Jing Li, Xi Wang, Fang Fang, Ling Han, Wanyin Wu, Sumei Wang
Summary: This study demonstrates that Fuzheng Kang-Ai (FZKA) decoction can inhibit the cell growth, proliferation, and invasion of lung adenocarcinoma (LUAD) and reverse the acquired resistance of gefitinib. FZKA exerts its effects by regulating the p-ERK1/2-EZH2-Snail/EGFR signaling pathway.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Xiang Zhao, Xianrun Hu, Qi Xie, Shenglan Qi, Zedong Xiang, Xin Sun, Zhejun Xie, Rui Dang, Limei Zhou, Wei Liu, Xuemei Cheng, Changhong Wang
Summary: This study investigated the effects of Fufangmuniziqi formula (FFMN) on Alzheimer's disease (AD) and the role of alkaloids, flavonoids, and saponins in the process. The results showed that FFMN improved cognitive and memory impairment in the AD mouse model. Alkaloids enhanced the cholinergic system, while flavonoids and saponins attenuated neuroinflammation and oxidative stress. These findings suggest that the combination of alkaloid, flavonoid, and saponin fractions derived from FFMN is a promising anti-AD agent.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Bangjian Dong, Ying Peng, Mengyue Wang, Chongsheng Peng, Xiaobo Li
Summary: This study elucidated the tissue distribution and excretion characteristics of the non-polysaccharide components of Sijunzi decoction in rats with spleen deficiency syndrome. It proposed new insights into the rationality of the compatibility of Sijunzi decoction.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Jung-Seop Kim, Man-Gi Kim, Ji Eun Ryu, Ye-Been Lee, Quan Feng Liu, Kwang Ki Kim, Seung-Hun Cho, Sung Joon Shin, Byung-Soo Koo, Hyung-Kyoon Choi
Summary: Co-treatment with WCW and donepezil shows promise in improving cognitive function and serum metabolic profiles in a scopolamine-induced AD model. This combination therapy may reduce tyrosine and methionine levels, enhancing cognitive function by mitigating known risk factors for AD. The study provides a foundation for developing other bioactive compounds in AD treatment.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Kuang-Hsing Chiang, Tain-Junn Cheng, Wei-Chih Kan, Hsien-Yi Wang, Jui-Chen Li, Yan-Ling Cai, Chia-Hui Cheng, Yi-Chien Liu, Chia-Yu Chang, Jiunn-Jye Chuu
Summary: The ethanolic extract of Orthosiphon aristatus (OA) demonstrated an improving effect on memory and could serve as a potential therapeutic target for the treatment of neurodegenerative diseases like Alzheimer's disease (AD).
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Meryem Tourabi, Asmae EL Ghouizi, Ghizlane Nouioura, Khaoula Faiz, Hind Elfatemi, Karima El-yagoubi, Badiaa Lyoussi, Elhoussine Derwich
Summary: Mentha longifolia is a native plant in Morocco, traditionally used to treat various diseases. This study analyzed the phytochemical profile of the aqueous extract of M. longifolia and evaluated its acute and subacute toxicity in mice. The results showed that M. longifolia extract is rich in phenolic compounds and has no observed toxicity up to a certain dosage limit.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Yue Zhang, Liang Li, Tao Chai, Han Xu, Hong-yan Du, Yan Jiang
Summary: Mulberry leaf multi-components (MMC) have hypoglycemic effects and can improve insulin resistance by activating the PI-3K/Akt signaling pathway. These findings highlight the multi-component, multi-target, and combined effects of MMC, and suggest it may be further developed as a hypoglycemic drug.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Correction
Plant Sciences
Shan Luo, Yuanchun Chen, Ruoxi Zhao, Donglai Ma, Yanmeng Zhao, Ying Zhang, Jianming Jiang, Wentao Yu
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Nittaya Chansiw, Pattranuch Chusri, Siwaporn Praman, Thaneeya Hawiset, Wannisa Sukhorum, Sorraya Champakam, Rawiwan Charoensup
Summary: This study evaluates the anti-inflammatory activity of Prabchompoothaweep (PCT) extract in an animal model. The results show that PCT significantly reduces inflammation and pro-inflammatory cytokines in acute and sub-acute inflammation. These findings suggest that PCT could be a new option for the treatment of inflammatory diseases.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Yanting Wang, Guoqiang Liang, Wei Mu, Shu Sun, Xuanyi Chen, Xiaofeng Xu
Summary: Bushen Tianjing Recipe (BTR) is a tonic-kidney formula of Traditional Chinese Medicine (TCM) with good therapeutic effects in clinical settings. The aim of this study was to investigate the effect of BTR on women's reproductive system by incubating miR-23a-induced KGN cells.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Jiayi Zhi, Li Yin, Zhoudong Zhang, Yaozhong Lv, Fan Wu, Yang Yang, Enming Zhang, Huanqiu Li, Ning Lu, Mengze Zhou, Qinghua Hu
Summary: This study verified the pharmacodynamics of JSW in the treatment of AD and explored its potential mechanism using network pharmacology, molecular docking, and experimental validation.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Review
Plant Sciences
Elizabeth Syowai Mutinda, Dong-Juan Zhang, Felix Wambua Muema, Elijah Mbandi Mkala, Emmanuel Nyongesa Waswa, Wyclif Ochieng Odago, Clintone Onyango Ochieng, Moses Kirega Gichua, John Kamau Muchuku, Elizabeth Kamande, Guang-Wan Hu
Summary: This article reviews the traditional uses, pharmacological properties, and phytoconstituents of Balanophora species, revealing that they contain diverse chemical compounds with interesting biological activities. However, research on many species in this genus is still lacking.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Luqi Cai, Yu Chen, Huizhong Xue, Yimeng Yang, Yuqi Wang, Junhe Xu, Chunyan Zhu, Long He, Yonghua Xiao
Summary: Salvia miltiorrhiza Bunge (SM) has been proven to have potential therapeutic effects for diabetic nephropathy (DN) through its multi-component, multi-target, and multi-pathway pharmacological effects.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Chao Wang, Rui-Jia Fu, Ding-Qiao Xu, Qian Zuo, Ji-Ping Liu, Yu-Ping Tang
Summary: This study aimed to explore the hepatoprotective effects of Shicao on CCl4-induced acute liver injury. A rat model of acute liver injury was established and liver function indices were assessed. Untargeted metabolomics was conducted to identify differential metabolites. Network pharmacology was used to construct a network of metabolite-reaction-enzyme-gene constituents, and key components and hub genes were screened. Shicao showed hepatoprotective effects against acute liver injury in rats.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)