Glucocorticoid treatment and endocrine pancreas function: implications for glucose homeostasis, insulin resistance and diabetes

Unraveling the functions of the membrane-bound glucocorticoid receptors: first clues on origin and functional activity

(2014) Cindy Strehl et al.   Annals of the New York Academy of Sciences

Increased incidence of pre-diabetes mellitus at a department of rheumatology: a retrospective study

(2014) Tomoki Origuchi et al.   Modern Rheumatology

Pancreatic Alpha-Cell Dysfunction Contributes to the Disruption of Glucose Homeostasis and Compensatory Insulin Hypersecretion in Glucocorticoid-Treated Rats

(2014) Alex Rafacho et al.   PLoS One

Effects of Low-Dose Prednisolone on Hepatic and Peripheral Insulin Sensitivity, Insulin Secretion, and Abdominal Adiposity in Patients With Inflammatory Rheumatologic Disease

(2013) Carolyn J. Petersons et al.   DIABETES CARE

Exogenous Glucocorticoids and a High-Fat Diet Cause Severe Hyperglycemia and Hyperinsulinemia and Limit Islet Glucose Responsiveness in Young Male Sprague-Dawley Rats

(2013) Jacqueline L. Beaudry et al.   ENDOCRINOLOGY

New Insights into the Anti-inflammatory Mechanisms of Glucocorticoids: An Emerging Role for Glucocorticoid-Receptor-Mediated Transactivation

(2013) Sofie Vandevyver et al.   ENDOCRINOLOGY

β-cell adaptation in a mouse model of glucocorticoid-induced metabolic syndrome

(2013) Liselotte Fransson et al.   JOURNAL OF ENDOCRINOLOGY

Optimized glucocorticoid therapy: Teaching old drugs new tricks

(2013) Cindy Strehl et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes

(2012) D. H. Jensen et al.   DIABETOLOGIA

Glucocorticoid treatment and impaired mood, memory and metabolism in people with diabetes: the Edinburgh Type 2 Diabetes Study

(2012) R. M. Reynolds et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Osteoblasts mediate the adverse effects of glucocorticoids on fuel metabolism

(2012) Tara C. Brennan-Speranza et al.   JOURNAL OF CLINICAL INVESTIGATION

Investigation of the mechanisms contributing to the compensatory increase in insulin secretion during dexamethasone-induced insulin resistance in rhesus macaques

(2012) Bethany P Cummings et al.   JOURNAL OF ENDOCRINOLOGY

Islet-cell dysfunction induced by glucocorticoid treatment: potential role for altered sympathovagal balance?

(2012) Daniël H. van Raalte et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

How glucocorticoid receptors modulate the activity of other transcription factors: A scope beyond tethering

(2012) Dariusz Ratman et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Glucocorticoid receptors recruit the CaMKIIα-BDNF-CREB pathways to mediate memory consolidation

(2012) Dillon Y Chen et al.   NATURE NEUROSCIENCE

Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells

(2011) Margot M.L. Linssen et al.   CELLULAR SIGNALLING

Morphofunctional Alterations in Endocrine Pancreas of Short- and Long-term Dexamethasone-treated Rats

(2011) A. Rafacho et al.   HORMONE AND METABOLIC RESEARCH

Ghrelin Directly Stimulates Glucagon Secretion from Pancreatic α-Cells

(2011) Jen-Chieh Chuang et al.   MOLECULAR ENDOCRINOLOGY

Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus

(2011) Per Westermark et al.   PHYSIOLOGICAL REVIEWS

Impairment of Rat Fetal Beta-Cell Development by Maternal Exposure to Dexamethasone during Different Time-Windows

(2011) Olivier Dumortier et al.   PLoS One

N-acetylcysteine protects pancreatic islet against glucocorticoid toxicity

(2011) Letícia P Roma et al.   REDOX REPORT

The adaptive compensations in endocrine pancreas from glucocorticoid-treated rats are reversible after the interruption of treatment

(2010) A. Rafacho et al.   Acta Physiologica

Monitoring adverse events of low-dose glucocorticoid therapy: EULAR recommendations for clinical trials and daily practice

(2010) M. C. van der Goes et al.   ANNALS OF THE RHEUMATIC DISEASES

Relationship between serum osteocalcin and glycaemic variability in Type 2 diabetes

(2010) Yu-Qian Bao et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Acute effects of hydrocortisone on the metabolic response to a glucose load: increase in the first-phase insulin secretion

(2010) Greisa Vila et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Acute and 2-week exposure to prednisolone impair different aspects of β-cell function in healthy men

(2010) Daniël H van Raalte et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice

(2010) Rucha Patel et al.   JOURNAL OF CLINICAL INVESTIGATION

High doses of dexamethasone induce increased β-cell proliferation in pancreatic rat islets

(2009) Alex Rafacho et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Short-term prednisone use antagonizes insulin's anabolic effect on muscle protein and glucose metabolism in young healthy people

(2009) Kevin R. Short et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

11 -Hydroxysteroid Dehydrogenase Type 1 Regulates Glucocorticoid-Induced Insulin Resistance in Skeletal Muscle

(2009) S. A. Morgan et al.   DIABETES

Involvement of the cholinergic pathway in glucocorticoid-induced hyperinsulinemia in rats

(2009) Nágela Angelini et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Glucocorticoidsin VivoInduce Both Insulin Hypersecretion and Enhanced Glucose Sensitivity of Stimulus-Secretion Coupling in Isolated Rat Islets

(2009) Alex Rafacho et al.   ENDOCRINOLOGY

Novel insights into glucocorticoid-mediated diabetogenic effects: towards expansion of therapeutic options?

(2009) D. H. van Raalte et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

The Pathogenetic Role of Cortisol in the Metabolic Syndrome: A Hypothesis

(2009) Panagiotis Anagnostis et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Functional Alterations in Endocrine Pancreas of Rats With Different Degrees of Dexamethasone-Induced Insulin Resistance

(2009) Alex Rafacho et al.   PANCREAS

Ghrelin Modulates Brain Activity in Areas that Control Appetitive Behavior

(2008) Saima Malik et al.   Cell Metabolism

Evidence that autonomic mechanisms contribute to the adaptive increase in insulin secretion during dexamethasone-induced insulin resistance in humans

(2008) B. Ahrén   DIABETOLOGIA

11β-Hydroxysteroid dehydrogenase type 1 regulates insulin and glucagon secretion in pancreatic islets

(2008) A. Swali et al.   DIABETOLOGIA

AMP-activated protein kinase mediates glucocorticoid-induced metabolic changes: a novel mechanism in Cushing’s syndrome

(2008) Mirjam Christ-Crain et al.   FASEB JOURNAL

Changes in Adenosine 5′-Monophosphate-Activated Protein Kinase as a Mechanism of Visceral Obesity in Cushing’s Syndrome

(2008) Blerina Kola et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Physiology of the pancreatic α-cell and glucagon secretion: role in glucose homeostasis and diabetes

(2008) Ivan Quesada et al.   JOURNAL OF ENDOCRINOLOGY

Osteocalcin differentially regulates β cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice

(2008) Mathieu Ferron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel insights into mechanisms of glucocorticoid action and the development of new glucocorticoid receptor ligands

(2008) M LOWENBERG et al.   STEROIDS