Purification and Analysis of the Interactions of Caspase-1 and ASC for Assembly of the Inflammasome

Self-oligomerization of ASC PYD Domain Prevents the Assembly of Inflammasome In Vitro

(2014) Kannan Badri Narayanan et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

(2014) Alvin Lu et al.   CELL

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Inflammasomes in cancer: a double-edged sword

(2014) Ryan Kolb et al.   Protein & Cell

The CARD plays a critical role in ASC foci formation and inflammasome signalling

(2012) Martina Proell et al.   BIOCHEMICAL JOURNAL

Dual Role of Apoptosis-Associated Speck-Like Protein Containing a CARD (ASC) in Tumorigenesis of Human Melanoma

(2012) Weimin Liu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Crystallization and preliminary X-ray crystallographic studies of the PYD domain of human NALP3

(2011) Ju Young Bae et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

Structural analyses of death domains and their interactions

(2011) Hyun Ho Park   APOPTOSIS

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

Interaction Patches of Procaspase-1 Caspase Recruitment Domains (CARDs) Are Differently Involved in Procaspase-1 Activation and Receptor-interacting Protein 2 (RIP2)-dependent Nuclear Factor κB Signaling

(2011) Kristof Kersse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly

(2011) Ju Young Bae et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Generalized semi-refolding methods for purification of the functional death domain superfamily

(2011) Tae-ho Jang et al.   JOURNAL OF BIOTECHNOLOGY

Identification and analysis of dominant negative mutants of RAIDD and PIDD

(2010) Tae-Ho Jang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Expression and function of the NALP3 inflammasome in rheumatoid synovium

(2009) Laeticia Kolly et al.   IMMUNOLOGY

Intracellular innate immunity in gouty arthritis: role of NALP3 inflammasome

(2009) Ru Liu-Bryan   IMMUNOLOGY AND CELL BIOLOGY

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

The Nod-Like Receptor (NLR) Family: A Tale of Similarities and Differences

(2008) Martina Proell et al.   PLoS One

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE