A novel role for the mono-ADP-ribosyltransferase PARP14/ARTD8 in promoting homologous recombination and protecting against replication stress

The ADP-ribosyltransferase PARP10/ARTD10 Interacts with Proliferating Cell Nuclear Antigen (PCNA) and Is Required for DNA Damage Tolerance

(2014) Claudia M. Nicolae et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PARI Overexpression Promotes Genomic Instability and Pancreatic Tumorigenesis

(2013) K. W. O'Connor et al.   CANCER RESEARCH

ARTD10 substrate identification on protein microarrays: regulation of GSK3β by mono-ADP-ribosylation

(2013) Karla LH Feijs et al.   Cell Communication and Signaling

Expanding functions of intracellular resident mono-ADP-ribosylation in cell physiology

(2013) Karla L. H. Feijs et al.   FEBS Journal

DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis

(2013) Valérie Bergoglio et al.   JOURNAL OF CELL BIOLOGY

Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D

(2013) Xing Lu et al.   Molecular Cancer

Regulation of DNA Damage Responses by Ubiquitin and SUMO

(2013) Stephen P. Jackson et al.   MOLECULAR CELL

Erratum: Macrodomain-containing proteins: regulating new intracellular functions of mono(ADP-ribosyl)ation

(2013) Karla L. H. Feijs et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains

(2013) Alexandra H. Forst et al.   STRUCTURE

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

(2013) Patricia Verheugd et al.   Nature Communications

A systematic analysis of the PARP protein family identifies new functions critical for cell physiology

(2013) Sejal Vyas et al.   Nature Communications

Methylation of Histone H3 on Lysine 79 Associates with a Group of Replication Origins and Helps Limit DNA Replication Once per Cell Cycle

(2013) Haiqing Fu et al.   PLoS Genetics

An Optimized RAD51 Inhibitor That Disrupts Homologous Recombination without Requiring Michael Acceptor Reactivity

(2012) Brian Budke et al.   JOURNAL OF MEDICINAL CHEMISTRY

New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

(2012) Bryan A. Gibson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells

(2012) Brian Budke et al.   NUCLEIC ACIDS RESEARCH

New readers and interpretations of poly(ADP-ribosyl)ation

(2012) Thomas Kalisch et al.   TRENDS IN BIOCHEMICAL SCIENCES

The complex basis underlying common fragile site instability in cancer

(2012) Efrat Ozeri-Galai et al.   TRENDS IN GENETICS

Understanding the molecular basis of common fragile sites instability: Role of the proteins involved in the recovery of stalled replication forks

(2011) Annapaola Franchitto et al.   CELL CYCLE

Genomic instability in breast and ovarian cancers: translation into clinical predictive biomarkers

(2011) Marieke A. Vollebergh et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ADP-ribosylation of histones by ARTD1: An additional module of the histone code?

(2011) Michael O. Hottiger   FEBS LETTERS

Inhibition of Homologous Recombination by the PCNA-Interacting Protein PARI

(2011) George-Lucian Moldovan et al.   MOLECULAR CELL

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

(2011) Claudia Lukas et al.   NATURE CELL BIOLOGY

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

ATR preferentially interacts with common fragile site FRA3B and the binding requires its kinase activity in response to aphidicolin treatment

(2010) Cheng Wan et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Purified human BRCA2 stimulates RAD51-mediated recombination

(2010) Ryan B. Jensen et al.   NATURE

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

(2010) Mary Ellen Moynahan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Maintaining genome stability at the replication fork

(2010) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The DNA-damage response: new molecular insights and new approaches to cancer therapy

(2009) Stephen P. Jackson   BIOCHEMICAL SOCIETY TRANSACTIONS

Y-family DNA polymerases in mammalian cells

(2009) Caixia Guo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

DNA Polymerase POLN Participates in Cross-Link Repair and Homologous Recombination

(2009) G.-L. Moldovan et al.   MOLECULAR AND CELLULAR BIOLOGY

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis

(2009) Kok Lung Chan et al.   NATURE CELL BIOLOGY

DNA damage tolerance: when it's OK to make mistakes

(2009) Debbie J Chang et al.   Nature Chemical Biology

Overexpression of RAD51 suppresses recombination defects: a possible mechanism to reverse genomic instability

(2009) David Schild et al.   NUCLEIC ACIDS RESEARCH

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Mechanisms of Dealing with DNA Damage-Induced Replication Problems

(2008) Magda Budzowska et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE