Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides

Long non-coding RNA-DANCR in human circulating monocytes: a potential biomarker associated with postmenopausal osteoporosis

(2015) Xiang Tong et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Up-regulation of long noncoding RNA MALAT1 contributes to proliferation and metastasis in esophageal squamous cell carcinoma

(2015) Liwen Hu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The landscape of long noncoding RNAs in the human transcriptome

(2015) Matthew K Iyer et al.   NATURE GENETICS

The rates of the major steps in the molecular mechanism of RNase H1-dependent antisense oligonucleotide induced degradation of RNA

(2015) Timothy A. Vickers et al.   NUCLEIC ACIDS RESEARCH

Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution

(2015) Moran N Cabili et al.   GENOME BIOLOGY

A pathophysiological view of the long non-coding RNA world

(2015) Federico Di Gesualdo et al.   Oncotarget

The functional role of long non-coding RNAs and epigenetics

(2014) Jinneng Cao   BIOLOGICAL PROCEDURES ONLINE

MALAT1 promotes the proliferation and metastasis of gallbladder cancer cells by activating the ERK/MAPK pathway

(2014) Xiang-Song Wu et al.   CANCER BIOLOGY & THERAPY

Long Noncoding RNA MALAT1 Regulates Endothelial Cell Function and Vessel Growth

(2014) Katharina M. Michalik et al.   CIRCULATION RESEARCH

The decalog of long non-coding RNA involvement in cancer diagnosis and monitoring

(2014) Tanja Kunej et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Involvement of satellite I noncoding RNA in regulation of chromosome segregation

(2014) Takashi Ideue et al.   GENES TO CELLS

Long Non-coding RNAHOTAIRIs Targeted and Regulated by miR-141 in Human Cancer Cells

(2014) Takeshi Chiyomaru et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antisense Oligonucleotides Capable of Promoting Specific Target mRNA Reduction via Competing RNase H1-Dependent and Independent Mechanisms

(2014) Timothy A. Vickers et al.   PLoS One

RNAi Factors Are Present and Active in Human Cell Nuclei

(2014) Keith T. Gagnon et al.   Cell Reports

Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes

(2014) Sebastiaan van Heesch et al.   GENOME BIOLOGY

The Varied Roles of Nuclear Argonaute-Small RNA Complexes and Avenues for Therapy

(2014) Jason P Ross et al.   Molecular Therapy-Nucleic Acids

Downregulated LncRNA-ANCR promotes osteoblast differentiation by targeting EZH2 and regulating Runx2 expression

(2013) Lin Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gene regulation by the act of long non-coding RNA transcription

(2013) Aleksandra E Kornienko et al.   BMC BIOLOGY

Long non-coding RNA HOTAIR, a driver of malignancy, predicts negative prognosis and exhibits oncogenic activity in oesophageal squamous cell carcinoma

(2013) X Li et al.   BRITISH JOURNAL OF CANCER

lincRNAs: Genomics, Evolution, and Mechanisms

(2013) Igor Ulitsky et al.   CELL

EZH2 takes the stage when BRCA1 loses

(2013) Lan Wang et al.   CELL CYCLE

The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing

(2013) Lukas Stalder et al.   EMBO JOURNAL

Antisense Transcript Long Noncoding RNA (lncRNA) HOTAIR is Transcriptionally Induced by Estradiol

(2013) Arunoday Bhan et al.   JOURNAL OF MOLECULAR BIOLOGY

NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies

(2013) Tetsuro Hirose et al.   MOLECULAR BIOLOGY OF THE CELL

Knockdown of β-catenin with Dicer-Substrate siRNAs Reduces Liver Tumor Burden In vivo

(2013) Henryk Dudek et al.   MOLECULAR THERAPY

RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond

(2013) Stephane E. Castel et al.   NATURE REVIEWS GENETICS

Molecular basis for improved gene silencing by Dicer substrate interfering RNA compared with other siRNA variants

(2013) Nicholas M. Snead et al.   NUCLEIC ACIDS RESEARCH

Human RNase H1 Is Associated with Protein P32 and Is Involved in Mitochondrial Pre-rRNA Processing

(2013) Hongjiang Wu et al.   PLoS One

On the classification of long non-coding RNAs

(2013) Lina Ma et al.   RNA Biology

NEAT1 Long Noncoding RNA and Paraspeckle Bodies Modulate HIV-1 Posttranscriptional Expression

(2013) Q. Zhang et al.   mBio

Hepatotoxic Potential of Therapeutic Oligonucleotides Can Be Predicted from Their Sequence and Modification Pattern

(2013) Peter H. Hagedorn et al.   Nucleic Acid Therapeutics

Long Noncoding RNA MALAT1 Controls Cell Cycle Progression by Regulating the Expression of Oncogenic Transcription Factor B-MYB

(2013) Vidisha Tripathi et al.   PLoS Genetics

Improved Performance of Anti-miRNA Oligonucleotides Using a Novel Non-Nucleotide Modifier

(2013) Kim A Lennox et al.   Molecular Therapy-Nucleic Acids

Genome Regulation by Long Noncoding RNAs

(2012) John L. Rinn et al.   Annual Review of Biochemistry

Intracellular Localization and Routing of miRNA and RNAi Pathway Components

(2012) Thomas Ohrt et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Suppression of progenitor differentiation requires the long noncoding RNA ANCR

(2012) M. Kretz et al.   GENES & DEVELOPMENT

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

Long intergenic non-coding RNA TUG1 is overexpressed in urothelial carcinoma of the bladder

(2012) Yonghua Han et al.   JOURNAL OF SURGICAL ONCOLOGY

Upregulation of the long non-coding rna hotair promotes esophageal squamous cell carcinoma metastasis and poor prognosis

(2012) Fang-Jun Chen et al.   MOLECULAR CARCINOGENESIS

Targeting nuclear RNA for in vivo correction of myotonic dystrophy

(2012) Thurman M. Wheeler et al.   NATURE

Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation

(2012) Farzaneh Modarresi et al.   NATURE BIOTECHNOLOGY

HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer

(2012) K Kim et al.   ONCOGENE

Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo

(2012) D. J. Foster et al.   RNA

Malat1 is not an essential component of nuclear speckles in mice

(2012) S. Nakagawa et al.   RNA

Emerging Roles for Long Non-Coding RNAs in Cancer and Neurological Disorders

(2012) Courtney N. Niland et al.   Frontiers in Genetics

Overexpression of Long Non-coding RNA HOTAIR Predicts Tumor Recurrence in Hepatocellular Carcinoma Patients Following Liver Transplantation

(2011) Zhe Yang et al.   ANNALS OF SURGICAL ONCOLOGY

Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers

(2011) R. Kogo et al.   CANCER RESEARCH

Conserved Function of lincRNAs in Vertebrate Embryonic Development despite Rapid Sequence Evolution

(2011) Igor Ulitsky et al.   CELL

ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs

(2011) Liuqing Yang et al.   CELL

An Overview of Sugar-Modified Oligonucleotides for Antisense Therapeutics

(2011) Thazha P. Prakash   CHEMISTRY & BIODIVERSITY

Control of RNA processing by a large non-coding RNA over-expressed in carcinomas

(2011) Rui Lin et al.   FEBS LETTERS

Long non-coding RNAs in Huntington's disease neurodegeneration

(2011) Rory Johnson   NEUROBIOLOGY OF DISEASE

An Upstream Open Reading Frame and the Context of the Two AUG Codons Affect the Abundance of Mitochondrial and Nuclear RNase H1

(2010) Y. Suzuki et al.   MOLECULAR AND CELLULAR BIOLOGY

The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

(2010) Vidisha Tripathi et al.   MOLECULAR CELL

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice

(2010) Xue-hai Liang et al.   NUCLEIC ACIDS RESEARCH

Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter

(2010) Yongjun Chu et al.   NUCLEIC ACIDS RESEARCH

A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo

(2010) Nidhi Gupta et al.   PLoS One

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Importin 8 Is a Gene Silencing Factor that Targets Argonaute Proteins to Distinct mRNAs

(2009) Lasse Weinmann et al.   CELL

An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles

(2009) Christine M. Clemson et al.   MOLECULAR CELL

Selection of hyperfunctional siRNAs with improved potency and specificity

(2009) Xiaowei Wang et al.   NUCLEIC ACIDS RESEARCH

MENε/β noncoding RNAs are essential for structural integrity of nuclear paraspeckles

(2009) Yasnory T. F. Sasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Methodological obstacles in knocking down small noncoding RNAs

(2009) A. Ploner et al.   RNA

Efficient oligonucleotide-mediated degradation of nuclear noncoding RNAs in mammalian cultured cells

(2009) T. Ideue et al.   RNA

MEN  /  nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles

(2008) H. Sunwoo et al.   GENOME RESEARCH

Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells

(2008) Thomas Ohrt et al.   NUCLEIC ACIDS RESEARCH

Chemical Modification of siRNAs for In Vivo Use

(2008) Mark A. Behlke   OLIGONUCLEOTIDES

A multifunctional human Argonaute2-specific monoclonal antibody

(2008) S. Rudel et al.   RNA