Detection of recurrent alternative splicing switches in tumor samples reveals novel signatures of cancer

Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers

(2014) Fran Supek et al.   CELL

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

Isoform-level gene signature improves prognostic stratification and accurately classifies glioblastoma subtypes

(2014) Sharmistha Pal et al.   NUCLEIC ACIDS RESEARCH

Exon identity crisis: disease-causing mutations that disrupt the splicing code

(2014) Timothy Sterne-Weiler et al.   GENOME BIOLOGY

Ontology-aware classification of tissue and cell-type signals in gene expression profiles across platforms and technologies

(2013) Young-suk Lee et al.   BIOINFORMATICS

Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition

(2013) Alika K Maunakea et al.   CELL RESEARCH

Endothelial, epithelial, and fibroblast cells exhibit specific splicing programs independently of their tissue of origin

(2013) P. Mallinjoud et al.   GENOME RESEARCH

Genome variation and personalized cancer medicine

(2013) T. J. Hudson   JOURNAL OF INTERNAL MEDICINE

RBM5, 6, and 10 Differentially Regulate NUMB Alternative Splicing to Control Cancer Cell Proliferation

(2013) Elias G. Bechara et al.   MOLECULAR CELL

Comprehensive molecular characterization of clear cell renal cell carcinoma

(2013)   NATURE

The Reactome pathway knowledgebase

(2013) David Croft et al.   NUCLEIC ACIDS RESEARCH

Fibulin-2 Is a Driver of Malignant Progression in Lung Adenocarcinoma

(2013) Brandi N. Baird et al.   PLoS One

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

SF3B1 Mutations Are Associated with Alternative Splicing in Uveal Melanoma

(2013) S. J. Furney et al.   Cancer Discovery

RNA sequencing of cancer reveals novel splicing alterations

(2013) Jeyanthy Eswaran et al.   Scientific Reports

Isoform level expression profiles provide better cancer signatures than gene level expression profiles

(2013) ZhongFa Zhang et al.   Genome Medicine

Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events

(2012) J. Liu et al.   GENOME RESEARCH

RBFOX2 Is an Important Regulator of Mesenchymal Tissue-Specific Splicing in both Normal and Cancer Tissues

(2012) J. P. Venables et al.   MOLECULAR AND CELLULAR BIOLOGY

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

Deep Sequence Analysis of Non-Small Cell Lung Cancer: Integrated Analysis of Gene Expression, Alternative Splicing, and Single Nucleotide Variations in Lung Adenocarcinomas with and without Oncogenic KRAS Mutations

(2012) Krishna R. Kalari et al.   Frontiers in Oncology

WT1 Mutants Reveal SRPK1 to Be a Downstream Angiogenesis Target by Altering VEGF Splicing

(2011) Elianna M. Amin et al.   CANCER CELL

Engagement of I-Branching  -1, 6-N-Acetylglucosaminyltransferase 2 in Breast Cancer Metastasis and TGF-  Signaling

(2011) H. Zhang et al.   CANCER RESEARCH

RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

(2011) Poulikos I. Poulikakos et al.   NATURE

Anti-angiogenic and tumor-suppressive roles of candidate tumor-suppressor gene, Fibulin-2, in nasopharyngeal carcinoma

(2011) E W L Law et al.   ONCOGENE

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

(2011) N. Stransky et al.   SCIENCE

Lung Squamous Cell Carcinoma mRNA Expression Subtypes Are Reproducible, Clinically Important, and Correspond to Normal Cell Types

(2010) M. D. Wilkerson et al.   CLINICAL CANCER RESEARCH

S100A13 is a new angiogenic marker in human melanoma

(2010) Daniela Massi et al.   MODERN PATHOLOGY

Alternative Splicing of SLC39A14 in Colorectal Cancer is Regulated by the Wnt Pathway

(2010) Kasper Thorsen et al.   MOLECULAR & CELLULAR PROTEOMICS

Global Profiling and Molecular Characterization of Alternative Splicing Events Misregulated in Lung Cancer

(2010) C. M. Misquitta-Ali et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of 5 novel genes methylated in breast and other epithelial cancers

(2010) Victoria K Hill et al.   Molecular Cancer

Exon-Level Microarray Analyses Identify Alternative Splicing Programs in Breast Cancer

(2010) A. Lapuk et al.   MOLECULAR CANCER RESEARCH

Regulation of Alternative Splicing by Histone Modifications

(2010) R. F. Luco et al.   SCIENCE

RNA-Seq gene expression estimation with read mapping uncertainty

(2009) Bo Li et al.   BIOINFORMATICS

An oncogenic isoform of HER2 associated with locally disseminated breast cancer and trastuzumab resistance

(2009) D. Mitra et al.   MOLECULAR CANCER THERAPEUTICS

Epigenetics in cancer: Targeting chromatin modifications

(2009) L. Ellis et al.   MOLECULAR CANCER THERAPEUTICS

Multiple Alternative Splicing Markers for Ovarian Cancer

(2008) R. Klinck et al.   CANCER RESEARCH

CD44 is of Functional Importance for Colorectal Cancer Stem Cells

(2008) L. Du et al.   CLINICAL CANCER RESEARCH

The kinesin KIF1B  acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor

(2008) S. Schlisio et al.   GENES & DEVELOPMENT

A p120 Catenin Isoform Switch Affects Rho Activity, Induces Tumor Cell Invasion, and Predicts Metastatic Disease

(2008) Masahiro Yanagisawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative Splicing in Colon, Bladder, and Prostate Cancer Identified by Exon Array Analysis

(2008) Kasper Thorsen et al.   MOLECULAR & CELLULAR PROTEOMICS