Primase-polymerases are a functionally diverse superfamily of replication and repair enzymes

Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair

(2015) J. Gouge et al.   EMBO JOURNAL

Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ

(2015) Tatiana Kent et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Archaeal replicative primases can perform translesion DNA synthesis

(2015) Stanislaw K. Jozwiakowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ

(2015) Tatiana Kent et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal Structure of the Human Primase

(2014) Andrey G. Baranovskiy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive molecular characterization of urothelial bladder carcinoma

(2014)   NATURE

Molecular dissection of the domain architecture and catalytic activities of human PrimPol

(2014) Benjamin A. Keen et al.   NUCLEIC ACIDS RESEARCH

Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins

(2014) Thomas A. Guilliam et al.   NUCLEIC ACIDS RESEARCH

Human PrimPol mutation associated with high myopia has a DNA replication defect

(2014) Benjamin A. Keen et al.   NUCLEIC ACIDS RESEARCH

A highly divergent archaeo-eukaryotic primase from the Thermococcus nautilus plasmid, pTN2

(2014) Sukhvinder Gill et al.   NUCLEIC ACIDS RESEARCH

hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity

(2013) Li Wan et al.   EMBO REPORTS

Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase

(2013) Sivaraja Vaithiyalingam et al.   JOURNAL OF MOLECULAR BIOLOGY

PrimPol Bypasses UV Photoproducts during Eukaryotic Chromosomal DNA Replication

(2013) Julie Bianchi et al.   MOLECULAR CELL

PPL2 Translesion Polymerase Is Essential for the Completion of Chromosomal DNA Replication in the African Trypanosome

(2013) Sean G. Rudd et al.   MOLECULAR CELL

PrimPol, an Archaic Primase/Polymerase Operating in Human Cells

(2013) Sara García-Gómez et al.   MOLECULAR CELL

Repriming of DNA synthesis at stalled replication forks by human PrimPol

(2013) Silvana Mourón et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ribonucleolytic resection is required for repair of strand displaced nonhomologous end-joining intermediates

(2013) E. J. Bartlett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of human primase reveal design of nucleotide elongation site and mode of Pol   tethering

(2013) M. L. Kilkenny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA Polymerase

(2013) Nigel C. Brissett et al.   Cell Reports

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

(2012) Marcin Imielinski et al.   CELL

Characterization of DNA Primase Complex Isolated from the Archaeon,Thermococcus kodakaraensis

(2012) Wiebke Chemnitz Galal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

A Second Mitochondrial DNA Primase Is Essential for Cell Growth and Kinetoplast Minicircle DNA Replication in Trypanosoma brucei

(2011) Jane C. Hines et al.   EUKARYOTIC CELL

Structure of a Preternary Complex Involving a Prokaryotic NHEJ DNA Polymerase

(2011) Nigel C. Brissett et al.   MOLECULAR CELL

Molecular architecture of a multifunctional MCM complex

(2011) June Sanchez-Berrondo et al.   NUCLEIC ACIDS RESEARCH

UV stalled replication forks restart by re-priming in human fibroblasts

(2011) Ingegerd Elvers et al.   NUCLEIC ACIDS RESEARCH

Template-dependent polymerization across discontinuous templates by the heterodimeric primase from the hyperthermophilic archaeon Sulfolobus solfataricus

(2011) Jinchuan Hu et al.   NUCLEIC ACIDS RESEARCH

A CD133-related gene expression signature identifies an aggressive glioblastoma subtype with excessive mutations

(2011) X. Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Escherichia coli Replisome Is Inherently DNA Damage Tolerant

(2011) J. T. P. Yeeles et al.   SCIENCE

Identification of a bifunctional primase–polymerase domain of corynephage BFK20 replication protein gp43

(2011) Nora Halgasova et al.   VIRUS RESEARCH

A Modified Family-B Archaeal DNA Polymerase with Reverse Transcriptase Activity

(2010) Stanislaw K. Jozwiakowski et al.   CHEMBIOCHEM

A Mitochondrial DNA Primase Is Essential for Cell Growth and Kinetoplast DNA Replication in Trypanosoma brucei

(2010) J. C. Hines et al.   MOLECULAR AND CELLULAR BIOLOGY

Aberrant expression of alternative DNA polymerases: A source of mutator phenotype as well as replicative stress in cancer

(2010) Jean-Sébastien Hoffmann et al.   SEMINARS IN CANCER BIOLOGY

Human African trypanosomiasis

(2009) Reto Brun et al.   LANCET

A biochemically active MCM-like helicase in Bacillus cereus

(2009) Martin Samuels et al.   NUCLEIC ACIDS RESEARCH

Structure and function of primase RepB' encoded by broad-host-range plasmid RSF1010 that replicates exclusively in leading-strand mode

(2009) S. Geibel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular modeling and functional characterization of the monomeric primase-polymerase domain from the Sulfolobus solfataricus plasmid pIT3

(2008) Santina Prato et al.   FEBS Journal

PCNA Ubiquitination and REV1 Define Temporally Distinct Mechanisms for Controlling Translesion Synthesis in the Avian Cell Line DT40

(2008) Charlotte E. Edmunds et al.   MOLECULAR CELL

Products and substrate/template usage of vaccinia virus DNA primase

(2008) Frank S. De Silva et al.   VIROLOGY