Human PrimPol mutation associated with high myopia has a DNA replication defect

The S229L Colon Tumor-associated Variant of DNA Polymerase β Induces Cellular Transformation as a Result of Decreased Polymerization Efficiency

(2014) Antonia A. Nemec et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Steric Gate of DNA Polymerase ι Regulates Ribonucleotide Incorporation and Deoxyribonucleotide Fidelity

(2014) Katherine A. Donigan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular dissection of the domain architecture and catalytic activities of human PrimPol

(2014) Benjamin A. Keen et al.   NUCLEIC ACIDS RESEARCH

hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity

(2013) Li Wan et al.   EMBO REPORTS

Exome sequencing reveals CCDC111 mutation associated with high myopia

(2013) Fuxin Zhao et al.   HUMAN GENETICS

PrimPol Bypasses UV Photoproducts during Eukaryotic Chromosomal DNA Replication

(2013) Julie Bianchi et al.   MOLECULAR CELL

PPL2 Translesion Polymerase Is Essential for the Completion of Chromosomal DNA Replication in the African Trypanosome

(2013) Sean G. Rudd et al.   MOLECULAR CELL

PrimPol, an Archaic Primase/Polymerase Operating in Human Cells

(2013) Sara García-Gómez et al.   MOLECULAR CELL

Repriming of DNA synthesis at stalled replication forks by human PrimPol

(2013) Silvana Mourón et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Colon Cancer-associated DNA Polymerase β Variant Induces Genomic Instability and Cellular Transformation

(2012) Antonia A. Nemec et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myopia

(2012) Ian G Morgan et al.   LANCET

Y-family DNA polymerases and their role in tolerance of cellular DNA damage

(2012) Julian E. Sale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Unlocking the Sugar “Steric Gate” of DNA Polymerases

(2011) Jessica A. Brown et al.   BIOCHEMISTRY

Structure of a Preternary Complex Involving a Prokaryotic NHEJ DNA Polymerase

(2011) Nigel C. Brissett et al.   MOLECULAR CELL

Structure and mechanism of human DNA polymerase η

(2010) Christian Biertümpfel et al.   NATURE

Increased Prevalence of Myopia in the United States Between 1971-1972 and 1999-2004

(2009) Susan Vitale   ARCHIVES OF OPHTHALMOLOGY

Homologous recombination in DNA repair and DNA damage tolerance

(2008) Xuan Li et al.   CELL RESEARCH

Genome instability: a mechanistic view of its causes and consequences

(2008) Andrés Aguilera et al.   NATURE REVIEWS GENETICS